Publications

Klehr, J., Zhao, J., Kron, A. S., Ward, T. R. and Köhler, V. (2020) “Streptavidin (Sav)-Based Artificial Metalloenzymes: Cofactor Design Considerations and Large-Scale Expression of Host Protein Variants”, in Iranzo O., R. A. (ed.) Peptide and Protein Engineering. New York: Humana, pp. 213–235. doi: 10.1007/978-1-0716-0720-6_12.   edoc
Bullock, R. M., Chen, J. G., Gagliardi, L., Chirik, P. J., Farha, O. K., Hendon, C. H., Jones, C. W., Keith, J. A., Klosin, J., Minteer, S. D., Morris, R. H., Radosevich, A. T., Rauchfuss, T. B., Strotman, N. A., Vojvodic, A., Ward, T. R., Yang, J. Y. and Surendranath, Y. (2020) “Using nature’s blueprint to expand catalysis with Earth-abundant metals”, Science. American Association for the Advancement of Science, 369(6505), p. 3183. doi: 10.1126/science.abc3183.   edoc | Open Access
Sabatino, V., Staub, D. and Ward, T. R. (2020) “Synthesis of N-Substituted Indoles via Aqueous Ring-Closing Metathesis”, Catalysis Letters. Springer, ‏151(1), pp. 17–7. doi: 10.1007/s10562-020-03271-3.   edoc
Samanta, A., Sabatino, V., Ward, T. R. and Walther, A. (2020) “Functional and morphological adaptation in DNA protocells via signal processing prompted by artificial metalloenzymes”, Nature Nanotechnology. Nature Research , 15(11), pp. 914–921. doi: 10.1038/s41565-020-0761-y.   edoc | Open Access
Davis, H. J., Häussinger, D., Ward, T. R. and Okamoto, Y. (2020) “A visible-light promoted amine oxidation catalyzed by a Cp*Ir complex”, ChemCatChem. Wiley, 12(18), pp. 4512–4516. doi: 10.1002/cctc.202000488.   edoc | Open Access
Serrano-Plana, J., Rumo, C., Rebelein, J. G., Peterson, R. L., Barnet, M. and Ward, T. R. (2020) “Enantioselective Hydroxylation of Benzylic C(sp; 3; )-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology”, Journal of the American Chemical Society, 142(24), pp. 10617–10623. doi: 10.1021/jacs.0c02788.   edoc | Open Access
Miller, K. R., Paretsky, J. D., Follmer, A. H., Heinisch, T., Mittra, K., Gul, S., Kim, I.-S., Fuller, F. D., Batyuk, A., Sutherlin, K. D., Brewster, A. S., Bhowmick, A., Sauter, N. K., Kern, J., Yano, J., Green, M. T., Ward, T. R. and Borovik, A. S. (2020) “Artificial Iron Proteins: Modeling the Active Sites in Non-Heme Dioxygenases”, Inorganic Chemistry. American Chemical Society, 59(9), pp. 6000–6009. doi: 10.1021/acs.inorgchem.9b03791.   edoc
Wu, S., Zhou, Y., Gerngross, D., Jeschek, M. and Ward, T. R. (2019) “Chemo-enzymatic cascades to produce cycloalkenes from bio-based resources”, Nature Communications. Nature Publishing Group, 10, p. 5060. doi: 10.1038/s41467-019-13071-y.   edoc | Open Access
Wu, S., Zhou, Y., Rebelein, J. G., Kuhn, M., Mallin, H., Zhao, J., Igareta, N. V. and Ward, T. R. (2019) “Breaking Symmetry: Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes”, Journal of the American Chemical Society. American Chemical Society, 141(40), pp. 15869–15878. doi: 10.1021/jacs.9b06923.   edoc | Open Access
Sabatino, V., Rebelein, J. G. and Ward, T. R. (2019) “‘Close-to-Release’: Spontaneous Bioorthogonal Uncaging Resulting from Ring-Closing Metathesis”, Journal of the American Chemical Society. American Chemical Society, 141(43), pp. 17048–17052. doi: 10.1021/jacs.9b07193.   edoc | Open Access
Bartolami, E., Basagiannis, D., Zong, L., Martinent, R., Okamoto, Y., Laurent, Q., Ward, T. R., Gonzalez-Gaitan, M., Sakai, N. and Matile, S. (2019) “Diselenolane-Mediated Cellular Uptake: Efficient Cytosolic Delivery of Probes, Peptides, Proteins, Artificial Metalloenzymes and Protein-Coated Quantum Dots”, Chemistry - A European Journal. Wiley, 25(16), pp. 4047–4051. doi: 10.1002/chem.201805900.   edoc | Open Access
Sabatino, V. and Ward, T. R. (2019) “Aqueous olefin metathesis: recent developments and applications”, Beilstein Journal of Organic Chemistry. Beilstein-Institut, 15, pp. 445–468. doi: 10.3762/bjoc.15.39.   edoc | Open Access
Davis, H. J. and Ward, T. R. (2019) “Artificial Metalloenzymes: Challenges and Opportunities”, ACS Central Science. American Chemical Society, 5(7), pp. 1120–1136. doi: 10.1021/acscentsci.9b00397.   edoc | Open Access
Guo, X., Okamoto, Y., Schreier, M. R., Ward, T. R. and Wenger, O. S. (2019) “Reductive Amination and Enantioselective Amine Synthesis by Photoredox Catalysis”, European Journal of Organic Chemistry. Wiley. doi: 10.1002/ejoc.201900777.   edoc | Open Access
Cheng, Y., Zong, L., Lopez-Andarias, J., Bartolami, E., Okamoto, Y., Ward, T. R., Sakai, N. and Matile, S. (2019) “Cell-Penetrating Dynamic-Covalent Benzopolysulfane Networks”, Angewandte Chemie International Edition. Wiley, 58(28), pp. 9522–9526. doi: 10.1002/anie.201905003.   edoc | Open Access
Liang, A. D., Serrano-Plana, J., Peterson, R. L. and Ward, T. R. (2019) “Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology: Enzymatic Cascades and Directed Evolution”, Accounts of Chemical Research. American Chemical Society, 52(3), pp. 585–595. doi: 10.1021/acs.accounts.8b00618.   edoc | Open Access
Rebelein, J. G., Cotelle, Y., Garabedian, B. and Ward, T. R. (2019) “Chemical Optimization of Whole-Cell Transfer Hydrogenation Using Carbonic Anhydrase as Host Protein”, ACS Catalysis. ACS Publications, 9(5), pp. 4173–4178. doi: 10.1021/acscatal.9b01006.   edoc | Open Access
Keller, S. G., Probst, B., Heinisch, T., Alberto, R. and Ward, T. R. (2018) “Photo-Driven Hydrogen Evolution by an Artificial Hydrogenase Utilizing the Biotin-Streptavidin Technology”, Helvetica Chimica Acta. Wiley, 101(4), p. e1800036. doi: 10.1002/hlca.201800036.   edoc | Open Access
Heinisch, T., Schwizer, F., Garabedian, B., Csibra, E., Jeschek, M., Vallapurackal, J., Pinheiro, V. B., Marlière, P., Panke, S. and Ward, T. R. (2018) “E. coli surface display of streptavidin for directed evolution of an allylic deallylase”, Chemical Science. Royal Society of Chemistry, 9(24), pp. 5383–5388. doi: 10.1039/c8sc00484f.   edoc | Open Access
Okamoto, Y., Kojima, R., Schwizer, F., Bartolami, E., Heinisch, T., Matile, S., Fussenegger, M. and Ward, T. R. (2018) “A cell-penetrating artificial metalloenzyme regulates a gene switch in a designer mammalian cell”, Nature Communications. Nature Research, 9, p. 1943. doi: 10.1038/s41467-018-04440-0.   edoc | Open Access
Christoffel, F. and Ward, T. R. (2018) “Palladium-Catalyzed Heck Cross-Coupling Reactions in Water: A Comprehensive Review”, Catalysis letters. Springer, 148(2), pp. 489–511. doi: 10.1007/s10562-017-2285-0.   edoc | Open Access
Zhao, J., Rebelein, J. G., Mallin, H., Trindler, C., Pellizzoni, M. M. and Ward, T. R. (2018) “Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in Escherichia coli’s Periplasm”, Journal of American Chemical Society. American Chemical Society, 140(41), pp. 13171–13175. doi: 10.1021/jacs.8b07189.   edoc | Open Access
Mann, S., Heinisch, T., Ward, T. R. and Borovik, A. S. (2018) “Coordination chemistry within a protein host: regulation of the secondary coordination sphere”, Chemical Communications. Royal Society of Chemistry, 54(35), pp. 4413–4416. doi: 10.1039/c8cc01931b.   edoc | Open Access
Pellizzoni, M. M., Schwizer, F., Wood, C. W., Sabatino, V., Cotelle, Y., Matile, S., Woolfson , D. N. and Ward, T. R. (2018) “Chimeric Streptavidins as Host Proteins for Artificial Metalloenzymes”, ACS Catalysis. American Chemical Society, 8(2), pp. 1476–1484. doi: 10.1021/acscatal.7b03773.   edoc | Open Access
Mallin, H. and Ward, T. R. (2018) “Streptavidin-Enzyme Linked Aggregates for the One-Step Assembly and Purification of Enzyme Cascades”, ChemCatChem. Wiley, 10(13), pp. 2810–2816. doi: 10.1002/cctc.201800162.   edoc | Open Access
Szponarski, M., Schwizer, F., Ward, T. R. and Gademann, K. (2018) “On-cell catalysis by surface engineering of live cells with an artificial metalloenzyme”, Communications Chemistry. Nature Research, 1(84), pp. 1–10. doi: 10.1038/s42004-018-0087-y.   edoc | Open Access
Hestericová, M., Heinisch, T., Alonso-Cotchico, L., Maréchal, J.-D., Vidossich, P. and Ward, T. R. (2018) “Directed Evolution of an Artificial Imine Reductase”, Angewandte Chemie - International Edition. Wiley, 57(7), pp. 1863–1868. doi: 10.1002/anie.201711016.   edoc | Open Access
Hestericova, M., Heinisch, T., Lenz, M. and Ward, T. R. (2018) “Ferritin encapsulation of artificial metalloenzymes: engineering a tertiary coordination sphere for an artificial transfer hydrogenase”, Dalton transactions. Royal Society of Chemistry, 47(32), pp. 10837–10841. doi: 10.1039/c8dt02224k.   edoc | Open Access
Zhao, J., Bachmann, D. G., Lenz, M., Gillingham, D. G. and Ward, T. R. (2018) “An artificial metalloenzyme for carbene transfer based on a biotinylated dirhodium anchored within streptavidin”, Catalysis science & technology. Royal Society of Chemistry, 8(9), pp. 2294–2298. doi: 10.1039/c8cy00646f.   edoc | Open Access
Guo, X., Okamoto, Y., Schreier, M. R., Ward, T. R. and Wenger, O. S. (2018) “Enantioselective Synthesis of Amines by Combining Photoredox and Enzymatic Catalysis in a Cyclic Reaction Network”, Chemical Science. Royal Society of Chemistry, 9, pp. 5052–5056. doi: 10.1039/C8SC01561A.   edoc | Open Access
Schwizer, F., Okamoto, Y., Heinisch, T., Gu, Y., Pellizzoni, M. M., Lebrun, V., Reuter, R., Köhler, V., Lewis, J. C. and Ward, T. R. (2018) “Artificial Metalloenzymes: Reaction Scope and Optimization Strategies”, Chemical Reviews. American Chemical Society, 118(1), pp. 142–231. doi: 10.1021/acs.chemrev.7b00014.   edoc | Open Access
Rebelein, J. G. and Ward, T. R. (2018) “In vivo catalyzed new-to-nature reactions”, Current Opinion in Biotechnology. Elsevier, 53, pp. 106–114. doi: 10.1016/j.copbio.2017.12.008.   edoc | Open Access
Jeschek, M., Panke, S. and Ward, T. R. (2018) “Artificial Metalloenzymes on the Verge of New-to-Nature Metabolism”, Trends in Biotechnology. Elsevier, 36(1), pp. 60–72. doi: 10.1016/j.tibtech.2017.10.003.   edoc | Open Access
Keller, S. G., Pannwitz, A., Mallin, H., Wenger, O. S. and Ward, T. R. (2017) “Streptavidin as a Scaffold for Light-Induced Long-Lived Charge Separation”, Chemistry - A European Journal. Wiley, 23(71), pp. 18019–18024. doi: 10.1002/chem.201703885.   edoc | Open Access
Mann, S., Heinisch, T., Ward, T. R. and Borovik, A. S. (2017) “Peroxide Activation Regulated by Hydrogen Bonds within Artificial Cu Proteins”, Journal of the American Chemical Society. American Chemical Society, 139(48), pp. 17289–17292. doi: 10.1021/jacs.7b10452.   edoc | Open Access
Okamoto, Y. and Ward, T. R. (2017) “Transfer Hydrogenation Catalyzed by Organometallic Complexes using NADH as Reductant in a Biochemical Context”, Biochemistry. American Chemical Society, 56, pp. 5223–5224. doi: 10.1021/acs.biochem.7b00809.   edoc | Open Access
Okamoto, Y. and Ward, T. R. (2017) “Supramolecular Enzyme Mimics”, in Atwood Ed., J. (ed.) Comprehensive Supramolecular Chemistry II. Oxford: Elsevier, pp. 459–510. doi: 10.1016/B978-0-12-409547-2.12551-X.   edoc
Seck, C., Mbaye, D. M., Coufourier, S., Lator, A., Lohier, J.-F., Poater, A., Ward, T. R., Gaillard, S. and Renaud, J.-L. (2017) “Alkylation of Ketones Catalyzed by Bifunctional Iron Complexes: From Mechanistic Understanding to Application”, ChemCatChem. Wiley, 9(23), pp. 4410–4416. doi: 10.1002/cctc.201701241.   edoc
Okamoto, Y. and Ward, T. R. (2017) “Cross-Regulation of an Artificial Metalloenzyme”, Angewandte Chemie International Edition, 56(34), pp. 10156–10160. doi: 10.1002/anie.201702181.   edoc | Open Access
Trindler, C. and Ward, T. R. (2017) “Artificial Metalloenzymes”, in Poli, R. (ed.) Effects of Nanoconfinement on Catalysis. Cham, Switzerland: Springer, pp. 49–82. doi: 10.1007/978-3-319-50207-6_3.   edoc
Liu, L., Cotelle, Y., Klehr, J., Sakai, N., Ward, T. R. and Matile, S. (2017) “Anion-π catalysis: Bicyclic products with four contiguous stereogenic centers from otherwise elusive diastereospecific domino reactions on π-acidic surfaces”, Chemical Science. Royal Society of Chemistry, 8(5), pp. 3770–3774. doi: 10.1039/C7SC00525C.   edoc | Open Access
Jeschek, M., Bahls, M. O., Schneider, V., Marlière, P., Ward, T. R. and Panke, S. (2017) “Biotin-independent strains of Escherichia coli for enhanced streptavidin production”, Metabolic Engineering. Elsevier, 40, pp. 33–40. doi: 10.1016/j.ymben.2016.12.013.   edoc | Open Access
Jeschek, M., Panke, S. and Ward, T. R. (2016) “Periplasmic Screening for Artificial Metalloenzymes”, Methods in enzymology. Elsevier, 580, pp. 539–556. doi: 10.1016/bs.mie.2016.05.037.   edoc
Rottmann, P., Ward, T. R. and Panke, S. (2016) “Compartmentalization - A Prerequisite for Maintaining and Changing an Identity”, Chimia. Swiss Chemical Society, 70(6), pp. 428–431. doi: 10.2533/chimia.2016.428.   edoc | Open Access
Okamoto, Y., Köhler, V. and Ward, T. R. (2016) “An NAD(P)H-Dependent Artificial Transfer Hydrogenase for Multienzymatic Cascades”, Journal of the American Chemical Society. American Chemical Society, 138(18), pp. 5782–5784. doi: 10.1021/jacs.6b02470.   edoc | Open Access
Cotelle, Y., Lebrun, V., Sakai, N., Ward, T. R. and Matile, S. (2016) “Anion–π Enzymes”, ACS Central Science. American Chemical Society, 2(6), pp. 388–393. doi: 10.1021/acscentsci.6b00097.   edoc | Open Access
Jeschek, M., Reuter, R., Heinisch, T., Trindler, C., Klehr, J., Panke, S. and Ward, T. R. (2016) “Directed evolution of artificial metalloenzymes for in vivo metathesis”, Nature. Nature Publishing Group, 537(7622), pp. 661–665. doi: 10.1038/nature19114.   edoc | Open Access
Jeschenk, M., Panke, S. and Ward, T. R. (2016) “Chapter Twenty-Three – Periplasmic Screening for Artificial Metalloenzymes”, Methods in Enzymology. Elsevier, 580, pp. 539–556. doi: 10.1016/bs.mie.2016.05.037.   edoc
Mann, S., Heinisch, T., Weitz, A. C., Hendrich, M. R., Ward, T. R. and Borovik, A. S. . (2016) “Modular Artificial Cupredoxins”, Journal of the American Chemical Society. American Chemical Society, 138(29), pp. 9073–9076. doi: 10.1021/jacs.6b05428.   edoc
Hestericova, M., Correro, M. R. ., Lenz, M. ., Corvini, P. F.-X., Shahgaldian, P. and Ward, T. R. (2016) “Immobilization of an Artificial Imine Reductase within Silica Nanoparticles Improves its Performance”, Chemical Communications . Royal Society of Chemistry, 52, pp. 9462–9465. doi: 10.1039/C6CC04604E.   edoc | Open Access
Ward, T. R. (2016) “Directed Evolution of Iridium-Substituted Myoglobin Affords Versatile Artificial Metalloenzymes for Enantioselective C−C Bond-Forming Reactions”, Angewandte Chemie International Edition. Wiley, 55(48), pp. 14909–14911. doi: 10.1002/anie.201607222.   edoc | Open Access
Okamoto, Y., Köhler, V., Paul, C. E. ., Hollmann, F. and Ward, T. R. (2016) “Efficient In Situ Regeneration of NADH Mimics by an Artificial Metalloenzyme”, ACS Catalysis. American Chemical Society, 6(6), pp. 3553–3557. doi: 10.1021/acscatal.6b00258.   edoc | Open Access
Heinisch, T. and Ward, T. R. (2016) “Artificial Metalloenzymes Based on the Biotin–Streptavidin Technology: Challenges and Opportunities”, Accounts of Chemical Research. American Chemical Society, 49(9), pp. 1711–1721. doi: 10.1021/acs.accounts.6b00235.   edoc | Open Access
Chatterjee, A., Mallin, H., Klehr, J., Vallapurackal, J., Finke, A. D., Vera, L., Marsh, M. and Ward, T. R. (2016) “An Enantioselective Artificial Suzukiase Based on the Biotin–Streptavidin Technology”, Chemical Science. Royal Society of Chemistry, 7(1), pp. 673–677. doi: 10.1039/C5SC03116H.   edoc | Open Access
Hyster, T. K. and Ward, T. R. (2016) “Genetic Optimization of Metalloenzymes: Enhancing Enzymes for Non-Natural Reactions”, Angewandte Chemie International Edition. Wiley, 55(26), pp. 7344–7357. doi: 10.1002/anie.201508816.   edoc | Open Access
Cotelle, Y., Benz, S., Avestro, A.-J., Ward, T. R., Sakai, N. and Matile, S. (2016) “Anion-π Catalysis of Enolate Chemistry: Rigidified Leonard Turns as a General Tool to Run Reactions on Aromatic Surfaces”, Angewandte Chemie International Edition. Wiley, 128(13), pp. 4347–4351. doi: 10.1002/ange.201600831.   edoc | Open Access
Chatterjee, A. and Ward, T. R. (2016) “Recent Advances in the Palladium Catalyzed Suzuki–Miyaura Cross-Coupling Reaction in Water”, Catalysis Letters. Springer, 146(4), pp. 820–840. doi: 10.1007/s10562-016-1707-8.   edoc | Open Access
Mérel, D. S., Gaillard, S., Ward, T. R. and Renaud , J.-L. (2016) “Achiral Cyclopentadienone Iron Tricarbonyl Complexes Embedded in Streptavidin: An Access to Artificial Iron Hydrogenases and Application in Asymmetric Hydrogenation”, Catalysis Letters. Springer, 146(3), pp. 564–569. doi: 10.1007/s10562-015-1681-6.   edoc
Mallin, H., Reuter, R., Hestericova, M. and Ward, T. R. (2016) “Library design and screening protocol for artificial metalloenzymes based on the biotin-streptavidin technology”, Nature Protocols. Nature Publishing Group, 11, pp. 835–852. doi: 10.1038/nprot.2016.019.   edoc
Milopolska, E., Kuss-Petermann, M., Neuburger, M., Wenger, O. and Ward, T. R. (2016) “N-Heterocyclic Carbene Ligands Bearing a Naphthoquinone Appendage: Synthesis and Coordination Chemistry”, Polyhedron. Elsevier, 103, pp. 261–266. doi: 10.1016/j.poly.2015.04.019.   edoc
Liu, Z., Lebrun, V., Kitanosono, T., Mallin, H., Köhler, V., Häussinger, D., Hilvert, D., Kobayashi, S. and Ward, T. R. (2016) “Upregulation of an Artificial Zymogen by Proteolysis”, Angewandte Chemie International Edition. Wiley, 55(38), pp. 11587–11590. doi: 10.1002/anie.201605010.   edoc | Open Access
Keller, S. G., Pannwitz, A., Schwizer, F., Klehr, J., Wenger, O. S. and Ward, T. R. (2016) “Light-driven electron injection from a biotinylated triarylamine donor to [Ru(diimine)3]2+-labeled streptavidin ”, Organic and Biomolecular Chemistry. Royal Society of Chemistry, 14(30), pp. 7197–7201. doi: 10.1039/C6OB01273F .   edoc | Open Access
Okamoto, Y., Ward, T. R. and Wenger, O. S. (2016) “From Photodriven Charge Accumulation to Fueling Enzyme Cascades in Molecular Factories”, Chimia. Schweizerische Chemische Gesellschaft, 70(6), pp. 395–397. doi: 10.2533/chimia.2016.395.   edoc | Open Access
Cotelle, Y., Chuard, N., Lascano, S., Lebrun, V., Wehlauch, R., Bohni, N., Loercher, S., Postupalenko, V., Reddy, S. T., Meier, W., Palivan, C. G., Gademann, K., Ward, T. R. and Matile, S. (2016) “Interfacing Functional Systems”, Chimia. Schweizerische Chemische Gesellschaft, 70(6), pp. 418–423. doi: 10.2533/chimia.2016.418.   edoc | Open Access
Quinto, T., Köhler, V., Häussinger, D. and Ward, T. R. (2015) “Artificial metalloenzymes for the diastereoselective reduction of NAD+ to NAD2H”, Organic and Biomolecular Chemistry. Royal Society of Chemistry, 13, pp. 357–360. doi: 10.1039/C4OB02071E.   edoc | Open Access
Zhao, J., Kajetanowicz, A. and Ward, T. R. (2015) “Carbonic anhydrase II as host protein for the creation of a biocompatible artificial metathesase”, Organic and Biomolecular Chemistry. Royal Society of Chemistry, 13(20), pp. 5652–5655. doi: 10.1039/C5OB00428D.   edoc | Open Access
Heinisch, T. and Ward, T. R. (2015) “Latest Developments in Metalloenzyme Design and Repurposing”, European Journal of Inorganic Chemistry. Wiley, (21), pp. 3406–3418. doi: 10.1002/ejic.201500408.   edoc | Open Access
Reuter, R. and Ward, T. R. (2015) “Profluorescent substrates for the screening of olefin metathesis catalysts”, Beilstein journal of organic chemistry. Beilstein-Institut, 11, pp. 1886–1892. doi: 10.3762/bjoc.11.203.   edoc
Heinisch, T., Pellizzoni, M., Dürrenberger, M., Tinberg, C. E., Köhler, V., Häussinger, D., Klehr, J., Baker, D. and Ward, T. R. (2015) “Improving the catalytic performance of an artificial metalloenzyme by computational design”, Journal of the American Chemical Society. American Chemical Society, 137(32), pp. 10414–10419. doi: 10.1021/jacs.5b06622.   edoc | Open Access
Fujieda, N., Schätti, J., Stuttfeld, E., Ohkubo, K., Maier, T., Fukuzumi, S. and Ward, T. R. (2015) “Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding”, Chemical Science. Royal Society of Chemistry, 6(7), pp. 4060–4065. doi: 10.1039/C5SC01065A.   edoc | Open Access
Reuter, R. and Ward, T. R. (2014) “D(+)-Biotin”, in Fuchs, P., Bode, J., Charette, A., and Rovis, T. (eds.) e-EROS Encyclopedia of Reagents for Organic Synthesis. London, UK: Wiley, pp. 1–4. doi: 10.1002/047084289X.rn01826.   edoc
Keller, S. G., Ringenberg, M. R., Häussinger, D. and Ward, T. R. (2014) “Evaluation of the Formate Dehydrogenase Activity of Three-Legged Pianostool Complexes in Dilute Aqueous Solution”, European Journal of Inorganic Chemistry. Wiley, 2014(34), pp. 5860–5864. doi: 10.1002/ejic.201402348.   edoc
Kajetanowicz, A., Chatterjee, A., Reuter, R. and Ward, T. R. (2014) “Biotinylated Metathesis Catalysts: Synthesis and Performance in Ring Closing Metathesis”, Catalysis Letters. Springer, 144(3), pp. 373–379.   edoc
Dürrenberger, M. and Ward, T. R. (2014) “Recent Achievments in the Design and Engineering of Artificial Metalloenzymes”, Current Opinion in Chemical Biology. Elsevier, 19, pp. 99–106. doi: 10.1016/j.cbpa.2014.01.018.   edoc
Genz, M., Köhler, V., Krauss, M., Singer, D., Hoffmann, R., Ward, T. R. and Sträter, N. (2014) “An Artificial Imine Reductase Based on the RNAse S Scaffold”, ChemCatChem. Wiley, 6(3), pp. 736–740. doi: 10.1002/cctc.201300995.   edoc
Nogueira, E. S., Schleier, T., Dürrenberger, M., Ballmer-Hofer, K., Ward, T. R. and Jaussi, R. (2014) “High-level secretion of recombinant full-length streptavidin in Pichia pastoris and its application to enantioselective catalysis”, Protein Expression and Purification. Elsevier, 93, pp. 54–63. doi: 10.1016/j.pep.2013.10.015.   edoc
Quinto, T., Köhler, V. and Ward, T. R. (2014) “Recent Trends in Biomimetic NADH Regeneration”, Topics in catalysis. Springer, 57(5), p. 321. doi: 10.1007/s11244-013-0187-y.   edoc
Quinto, T., Schwizer, F., Zimbron, J. M., Morina, A., Köhler, V. and Ward, T. R. (2014) “Expanding the Chemical Diversity in Artificial Imine Reductases Based on the Biotin-Streptavidin Technology”, ChemCatChem. Wiley, 6(4), pp. 1010–1014. doi: 10.1002/cctc.201300825.   edoc
Munoz-Robles, V., Dürrenberger, M., Tillmann, H., Lledos, A. ., Schirmer, T., Ward, T. R. and Maréchal, J.-D. (2014) “Structural, Kinetic, and Docking Studies of Artificial Imine Reductases Based on Biotin–Streptavidin Technology: An Induced Lock-and-Key Hypothesis”, Journal of the American Chemical Society. American Chemical Society, 136(44), pp. 15676–15683. doi: 10.1021/ja508258t.   edoc
Wilson, Y. M., Dürrenberger, M., Nogueira, E. S. and Ward, T. R. (2014) “Neutralizing the Detrimental Effect of Glutathione on Precious Metal Catalysts”, Journal of the American Chemical Society. American Chemical Society, 136(25), pp. 8928–8932. doi: 10.1021/ja500613n.   edoc
Munoz-Robles, V., Vidossich, P., Lledos, A. ., Ward, T. R. and Maréchal, J.-D. (2014) “Computational Insights on an Artificial Imine Reductase Based on the Biotin–Streptavidin Technology”, ACS Catalysis. American Chemical Society, 4(3), pp. 833–842. doi: 10.1021/cs400921n.   edoc
Ward, T. R. (2013) “Author Profile: Thomas Ward”, Angewandte Chemie International Edition. Wiley, 52(18), p. 4722. doi: 10.1002/anie.201208430.   edoc
Hamels, D. R. and Ward, T. R. (2013) “Biomacromolecules as Ligands for Artificial Metalloenzymes”, in Comprehensive Inorganic Chemistry II . Elsevier, pp. 737–761. doi: 10.1016/B978-0-08-097774-4.00626-4.   edoc
Praneeth, V. K. K. and Ward, T. R. (2013) “Metal-Catalyzed Organic Transformations Inside a Protein Scaffold Using Artificial Metalloenzymes”, in Coordination Chemistry in Protein Cages: Principles, Design, and Applications. Wiley, pp. 203–220. Available at: http://eu.wiley.com/WileyCDA/WileyTitle/productCd-1118078578.html.   edoc
Schmid, M. H., Ward, T. R. and Meuwly, M. (2013) “Towards a Broadly Applicable Force Field for d6-piano Stool Complexes”, Journal of Chemical Theory and Computation. American Chemical Society, 9(5), pp. 2313–2323. doi: 10.1021/ct301080d.   edoc
Schwizer, F., Köhler, V., Dürrenberger, M., Knörr, L. and Ward, T. R. (2013) “Genetic Optimization of the Catalytic Efficiency of Artificial Imine Reductases Based on the Biotin-Streptavidin Technology”, ACS Catalysis. American Chemical Society, 3 (8), pp. 1752–1755. doi: 10.1021/cs400428r.   edoc
Monnard, F. W., Nogueira, E. S., Heinisch, T., Schirmer, T. and Ward, T. R. (2013) “Human Carbonic Anhydrase II as Host Protein for the Creation of Artificial Metalloenzymes : the Asymmetric Transfer Hydrogenation of Imines”, Chemical Science. Royal Society of Chemistry, 4(6), p. 3269. doi: 10.1039/C3SC51065D.   edoc | Open Access
Bereau, T., Kramer, C., Monnard, F. W., Nogueira, E. S., Ward, T. R. and Meuwly, M. (2013) “Scoring Multipole Electrostatics in Condensed-Phase Atomistic Simulations”, Journal of Physical Chemistry B. American Chemical Society, 117(18), pp. 5460–5471. doi: 10.1021/jp400593c.   edoc
Heinisch, T., Langowska, K., Tanner, P., Reymond, J.-L., Meier, W., Palivan, C. and Ward, T. R. (2013) “Fluorescence-Based Assay for the Optimization of the Activity of Artificial Transfer Hydrogenase within a Biocompatible Compartment”, ChemCatChem. Wiley, 5(3), pp. 720–723. doi: 10.1002/cctc.201200834.   edoc
Zimbron, J. M., Heinisch, T., Schmid, M., Hamels, D., Nogueira, E. S., Schirmer, T. and Ward, T. R. (2013) “A Dual Anchoring Strategy for the Localization and Activation of Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology”, Journal of the American Chemical Society. American Chemical Society, 135(14), pp. 5384–5388. doi: 10.1021/ja309974s.   edoc | Open Access
Koehler, V., Wilson, Y. M., Duerrenberger, M., Ghislieri, D., Churakova, E., Quinto, T., Knoerr, L., Haeussinger, D., Hollmann, F., Turner, N. J. and Ward, T. R. (2013) “Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes”, Nature Chemistry. Nature, 5, pp. 93–99. doi: 10.1038/nchem.1498.   edoc
Hyster, T. K., Knoerr, L., Ward, T. R. and Rovis, T. (2012) “Biotinylated Rh(III) complexes in engineered streptavidin for accelerated asymmetric C-H activation”, Science. American Association for the Advancement of Science, 338(6106), pp. 500–503. doi: 10.1126/science.1226132.   edoc
Oohora, K., Burazerovic, S., Onoda, A., Wilson, Y. M., Ward, T. R. and Hayashi, T. (2012) “Chemically Programmed Supramolecular Assembly of Hemoprotein and Streptavidin with Alternating Alignment”, Angewandte Chemie International Edition. Wiley, 51(16), pp. 3818–3821. doi: 10.1002/anie.201107067.   edoc
Amrein, B., Schmid, M., Collet, G., Cuniasse, P., Gilardoni, F., Seebeck, F. P. and Ward, T. R. (2012) “Identification of two-histidines one-carboxylate binding motifs in proteins amenable to facial coordination to metals”, Metallomics. Royal Society of Chemistry, 4(4), pp. 379–388. doi: 10.1039/C2MT20010D.   edoc
Praneeth, V. K. K., Ringenberg, M. R. and Ward, T. R. (2012) “Redox-Active Ligands in Catalysis”, Angewandte Chemie International Edition. Wiley, 51(41), pp. 10228–10234. doi: 10.1002/anie.201204100.   edoc
Schmid, M., Nogueira, E. S., Monnard, F. W., Ward, T. R. and Meuwly, M. (2012) “Arylsulfonamides as Inhibitors for Carbonic Anhydrase : Prediction & Validation”, Chemical Science. Royal Society of Chemistry, 3(3), pp. 690–700. doi: 10.1039/C1SC00628B.   edoc | Open Access
Lo, C., Ringenberg, M., Gnandt, D., Wilson, Y. and Ward, T. R. (2011) “Artificial metalloenzymes for olefin metathesis based on the biotin-(strept)avidin technology”, Chemical Communications. Royal Society of Chemistry, 47(44), pp. 12065–12067. doi: 10.1039/c1cc15004a.   edoc
Creus, M. and Ward, T. R. (2011) “Design and Evolution of Artificial Metalloenzymes: Biomimetic Aspects”, Progress In Inorganic Chemistry. Wiley, 57, pp. 203–254. doi: 10.1002/9781118148235.ch4.   edoc
Ward, T. R. (2011) “Artificial Metalloenzymes Based on the Biotin-Avidin Technology : Enantio-selective Catalysis and Beyond”, Accounts of Chemical Research. American Chemical Society, 44(1), pp. 47–57. doi: 10.1021/ar100099u.   edoc
Dürrenberger, M., Heinisch, T., Wilson, Y., Rossel, T., Nogueira, E., Knörr, L., Mutschler, A., Kersten, K., Zimbron, M., Pierron, J., Schirmer, T. and Ward, T. R. (2011) “Artificial Transfer Hydrogenases for the Enantioselective Reduction of Cyclic Imines”, Angewandte Chemie International Edition. Wiley, 50(13), pp. 3026–3029. doi: 10.1002/anie.201007820.   edoc
Clemens, M., Gillingham, D., Ward, T. R. and Hilvert, D. (2011) “An Artificial Metalloenzyme for Olefin Metathesis”, Journal of the Chemical Society, Chemical Communications. Royal Society of Chemistry, 47(44), pp. 12068–12070. doi: 10.1039/c1cc15005g.   edoc
Köhler, V., Mao, J., Heinisch, T., Pordea, A., Sardo, A., Wilson, Y., Knörr, L., Creus, M., Prost, J.-C., Schirmer, T. and Ward, T. R. (2011) “OsO4⋅Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis-Dihydroxylation of Olefins”, Angewandte Chemie International Edition. Wiley, 50(46), pp. 10863–10866. doi: 10.1002/anie.201103632.   edoc
Ringenberg, M. and Ward, T. R. (2011) “Merging the Best of Two Worlds : Artificial Metalloenzymes for Enantioselective Catalysis”, Chemical Communications. Royal Society of Chemistry, 47, (30), pp. 8470–8476. doi: 10.1039/c1cc11592h.   edoc
Sardo, A., Wohlschlager, T., Lo, C., Zoller, H., Ward, T. R. and Creus, M. (2011) “Burkavidin: A novel secreted biotin-binding protein from the human pathogen Burkholderia pseudomallei”, Protein Expression and Purification. Elsevier, 77(2), pp. 131–139. doi: 10.1016/j.pep.2011.01.003.   edoc
Monnard, F. W., Heinisch, T., Nogueira, E. S., Schirmer, T. and Ward, T. R. (2011) “Human Carbonic Anhydrase II as a host for piano-stool complexes bearing a sulfonamide anchor”, Chemical Communications. Royal Society of Chemistry, 47(29), pp. 8238–8240. doi: 10.1039/c1cc10345h .   edoc
Panek, J. J., Ward, T. R., Jezierska-Mazzarello, A. and Novic, M. (2010) “Flexibility of a biotinylated ligand in artificial metalloenzymes based on streptavidin-an insight from molecular dynamics simulations with classical and ab initio force fields”, Journal of Computer-Aided Molecular Design. Springer , 24(9), pp. 719–732. doi: 10.1007/s10822-010-9369-x.   edoc
Heinisch, T. and Ward, T. R. (2010) “Design strategies for the creation of artificial metalloenzymes”, Current Opinion in Chemical Biology. Elsevier, 14(2), pp. 184–199. doi: 10.1016/j.cbpa.2009.11.026.   edoc
Koehler, V. and Ward, T. R. (2010) “Design of a Functional Nitric Oxide Reductase within a Myoglobin Scaffold”, Chembiochem : a European journal of chemical biology. Wiley, 118(8), pp. 81049–81051. doi: 10.1002/cbic.201000093.   edoc | Open Access
Koehler, V., Wilson, Y. M., Lo, C., Sardo, A. and Ward, T. R. (2010) “Protein-based hybrid catalysts-design and evolution”, Current Opinion in Biotechnology. Elsevier, 21(6), pp. 744–752. doi: 10.1016/j.copbio.2010.09.004.   edoc
Pordea, A., Creus, M., Letondor, C., Ivanova, A. and Ward, T. R. (2010) “Improving the enantioselectivity of artificial transfer hydrogenases based on the biotin-streptavidin technology by combinations of point mutations”, Inorganica Chimica Acta. Elsevier, 363(3), pp. 601–604. doi: 10.1016/j.ica.2009.02.001.   edoc
Zimbron, J. M., Sardo, A., Heinisch, T., Wohlschlager, T., Gradinaru, J., Massa, C., Schirmer, T., Creus, M. and Ward, T. R. (2010) “Chemo-Genetic Optimization of DNA Recognition by Metallodrugs using a Presenter-Protein Strategy”, Chemistry - A European Journal. Wiley, 16(43), pp. 12883–12889. doi: 10.1002/chem.201001573.   edoc
Pordea, A. and Ward, T. R. (2009) “Artificial metalloenzymes : combining the best features of homogeneous and enzymatic catalysis”, Synlett. Georg Thieme Verlag, 2009(16), pp. 3225–3236. doi: 10.1055/s-0029-1218305.   edoc
Fuerstenberg, A., Kel, O., Gradinaru, J., Ward, T. R., Emery, D., Bollot, G., Mareda, J. and Vauthey, E. (2009) “Site-Dependent Excited-State Dynamics of a Fluorescent Probe Bound to Avidin and Streptavidin”, ChemPhysChem. Wiley, 10(9/10), pp. 1517–1532. doi: 10.1002/cphc.200900132.   edoc
Pordea, A., Mathis, D. and Ward, T. R. (2009) “IIncorporation of biotinylated manganese-salen complexes into streptavidin: New artificial metalloenzymes for enantioselective sulfoxidation”, Journal of Organometallic Chemistry. Elsevier, 694(6), pp. 930–936. doi: 10.1016/j.jorganchem.2008.11.023.   edoc
Panek, J. J., Ward, T. R., Jezierska, A. and Novic, M. (2009) “Effects of tryptophan residue fluorination on streptavidin stability and biotin-streptavidin interactions via molecular dynamics simulations”, Journal of Molecular Modeling. Springer, 15(3), pp. 257–266. doi: 10.1007/s00894-008-0382-0.   edoc
Pordea, A. and Ward, T. R. (2008) “Chemogenetic protein engineering : an efficient tool for the optimization of artificial metalloenzymes”, Chemical Communications. Royal Society of Chemistry, 44(36), pp. 4239–4249. doi: 10.1039/B806652C.   edoc
Pierron, J., Malan, C., Creus, M., Gradinaru, J., Hafner, I., Ivanova, A., Sardo, A. and Ward, T. R. (2008) “Artificial metalloenzymes for asymmetric allylic alkylation on the basis of the biotin-avidin technology”, Angewandte Chemie International Edition. Wiley, 47(4), pp. 701–705. doi: 10.1002/anie.200703159.   edoc
Ward, T. R. (2008) “Artificial enzymes made to order : combination of computational design and directed evolution”, Angewandte Chemie International Edition. Wiley, 47(41), pp. 7802–7803. doi: 10.1002/anie.200802865.   edoc
Creus, M., Pordea, A., Rossel, T., Sardo, A., Letondor, C., Ivanova, A., LeTrong, I., Stenkamp, R. E. and Ward, T. R. (2008) “X-ray structure and designed evolution of an artificial transfer hydrogenase”, Angewandte Chemie International Edition. Wiley, 47(8), pp. 1400–1404. doi: 10.1002/anie.200704865.   edoc
Han, A., Creus, M., Schuermann, G., Linder, V., Ward, T. R., de Rooij, N. F. and Staufer, U. (2008) “Label-free detection of single protein molecules and protein-protein interactions using synthetic nanopores”, Analytical Chemistry. American Chemical Society, 80(12), pp. 4651–4658. doi: 10.1021/ac7025207.   edoc
Steinreiber, J. and Ward, T. R. (2008) “Artificial metalloenzymes as selective catalysts in aqueous media”, Coordination Chemistry Reviews. Elsevier , 252(5-7), pp. 751–766. doi: 10.1016/j.ccr.2007.09.016.   edoc
Mao, J. and Ward, T. R. (2008) “Artificial metalloenzymes for enantioselective catalysis based on the biotin-avidin technology”, Chimia. Schweizerische Chemische Gesellschaft, 62(12), pp. 956–961. doi: 10.2533/chimia.2008.956.   edoc | Open Access
Pordea, A., Creus, M., Panek, J., Duboc, C., Mathis, D., Novic, M. and Ward, T. R. (2008) “Artificial metalloenzyme for enantioselective sulfoxidation based on vanadyl-loaded streptavidin”, Journal of the American Chemical Society. American Chemical Society, 130(25), pp. 8085–8088. doi: 10.1021/ja8017219.   edoc
Creus, M. and Ward, T. R. (2007) “Designed evolution of artificial metalloenzymes: Protein catalysts made to order”, Organic and Biomolecular Chemistry. Royal Society of Chemistry, 5(12), pp. 1835–1844. doi: 10.1039/B702068F.   edoc
Burazerovic, S., Gradinaru, J., Pierron, J. and Ward, T. R. (2007) “Hierarchical self-assembly of one-dimensional streptavidin bundles as a collagen mimetic for the biomineralization of calcite”, Angewandte Chemie International Edition. Wiley, 46(29), pp. 5510–5514. doi: 10.1002/anie.200701080.   edoc
Rusbandi, U. E., Lo, C., Skander, M., Ivanova, A., Creus, M., Humbert, N. and Ward, T. R. (2007) “Second Generation Artificial Hydrogenases Based on the Biotin-Avidin Technology: Improving Activity, Stability and Selectivity by Introduction of Enantiopure Amino Acid Spacers”, Advanced Synthesis and Catalysis. Wiley, 349(11/12), pp. 1923–1930. doi: 10.1002/adsc.200700022.   edoc
Mazurek, S., Ward, T. R. and Novic, M. (2007) “Counter propagation artificial neural networks modeling of an enantioselectivity of artificial metalloenzymes”, Molecular Diversity. Springer, 11(3-4), pp. 141–152. doi: 10.1007/s11030-008-9068-x.   edoc
Rusbandi, U. E., Skander, M., Ivanova, A., Malan, C. and Ward, T. R. (2007) “Second-generation artificial hydrogenases based on the biotin–avidin technology: Improving selectivity and organic solvent tolerance by introduction of an (R)-proline spacer”, Comptes Rendus Chimie. Elsevier, 10(8), pp. 678–683. doi: 10.1016/j.crci.2007.02.020.   edoc
Letondor, C., Pordea, A., Humbert, N., Ivanova, A., Mazurek, S., Novic, M. and Ward, T. R. (2006) “Artificial transfer hydrogenases based on the biotin-(strept)avidin technology : fine tuning the selectivity by saturation mutagenesis of the host protein”, Journal of the American Chemical Society. American Chemical Society, 128(25), pp. 8320–8328. doi: 10.1021/ja061580o.   edoc
Letondor, C. and Ward, T. R. (2006) “Artificial Metalloenzymes for Enantioselective Catalysis: Recent Advances”, ChemBioChem. Wiley, 7(12), pp. 1845–1852. doi: 10.1002/cbic.200600264.   edoc
Delahaye, S., Loosli, C., Liu, S.-X., Decurtins, S., Labat, G., Neels, A., Loosli, A., Ward, T. R. and Hauser, A. (2006) “Inter- and Intramolecular Interactions in Some Supramolecular Photochemical Systems”, Advanced Functional Materials. Wiley, 16(2), pp. 286–295. doi: 10.1002/adfm.200500329.   edoc
Loosli, A., Rusbandi, U. E., Gradinaru, J., Bernauer, K., Schlaepfer, C. W., Meyer, M., Mazurek, S., Novic, M. and Ward, T. R. (2006) “(Strept)avidin as Host for Biotinylated Coordination Complexes:  Stability, Chiral Discrimination, and Cooperativity”, Inorganic Chemistry. American Chemical Society, 45(2), pp. 660–668. doi: 10.1021/ic051405t.   edoc
Le Trong, I., Humbert, N., Ward, T. R. and Stenkamp, R. E. (2006) “Crystallographic Analysis of a Full-length Streptavidin with Its C-terminal Polypeptide Bound in the Biotin Binding Site”, Journal of Molecular Biology. Elsevier, 356(3), pp. 738–745. doi: 10.1016/j.jmb.2005.11.086.   edoc
Thomas, C. M. and Ward, T. R. (2005) “Artificial metalloenzymes: proteins as hosts for enantioselective catalysis ”, Chemical Society Reviews. Royal Society of Chemistry, 34(4), pp. 337–346. doi: 10.1039/B314695M.   edoc
Letondor, C., Humbert, N. and Ward, T. R. (2005) “Artificial metalloenzymes based on biotin-avidin technology for the enantioselective reduction of ketones by transfer hydrogenation”, Proceedings of the National Academy of Sciences. National Academy of Sciences, 102(13), pp. 4683–4687. doi: 10.1073/pnas.0409684102.   edoc
Skander, M., Malan, C., Ivanova, A. and Ward, T. R. (2005) “Chemical optimization of artificial metalloenzymes based on the biotin-avidin technology : (S)-selective and solvent-tolerant hydrogenation catalysts via the introduction of chiral amino acid spacers”, Chemical Communications. Royal Society of Chemistry, 41(38), pp. 4815–4817. doi: 10.1039/B509015F .   edoc
Ward, T. R. (2005) “Artificial Metalloenzymes for Enantioselective Catalysis Based on the Noncovalent Incorporation of Organometallic Moieties in a Host Protein”, Chemistry - A European Journal. Wiley, 11(13), pp. 3798–3804. doi: 10.1002/chem.200401232.   edoc
Thomas, C. M., Letondor, C., Humbert, N. and Ward, T. R. (2005) “Aqueous oxidation of alcohols catalyzed by artificial metalloenzymes based on the biotin-avidin technology”, Journal of Organometallic Chemistry. Elsevier, 690(20), pp. 4488–4491. doi: 10.1016/j.jorganchem.2005.02.001.   edoc
Thomas, C. M. and Ward, T. R. (2005) “Design of artificial metalloenzymes”, Applied Organometallic Chemistry. Wiley, 19(1), pp. 35–39. doi: 10.1002/aoc.726.   edoc
Klein, G., Humbert, N., Gradinaru, J., Ivanova, A., Gilardoni, F., Rusbandi, U. E. and Ward, T. R. (2005) “Tailoring the Active Site of Chemzymes by Using a Chemogenetic-Optimization Procedure: Towards Substrate-Specific Artificial Hydrogenases Based on the Biotin–Avidin Technology”, Angewandte Chemie International Edition. Wiley, 44(47), pp. 7764–7767. doi: 10.1002/anie.200502000.   edoc
Vieille-Petit, L., Suess-Fink, G., Therrien, B., Ward, T. R., Stoeckli-Evans, H., Labat, G., Karmazin-Brelot, L., Neels, A., Buergi, T., Finke, R. G. and Hagen, C. M. (2005) “Synthesis and Characterization of Tetrahedral Ru3O Clusters with Intrinsic Framework Chirality:  A Chiral Probe of the Intact Cluster Catalysis Concept”, Organometallics. American Chemical Society, 24(25), pp. 6104–6119. doi: 10.1021/om050643t.   edoc
Humbert, N., Zocchi, A. and Ward, T. R. (2005) “Electrophoretic behavior of streptavidin complexed to a biotinylated probe: A functional screening assay for biotin-binding proteins”, Electrophoresis. Wiley, 26(1), pp. 47–52. doi: 10.1002/elps.200406148.   edoc
Vieille-Petit, L., Therrien, B., Suss-Fink, G. and Ward, T. R. (2004) “Erratum to ‘Isolation and single-crystal X-ray structure analysis of the catalyst-substrate host–guest complexes [C6H6⊂H3Ru3{C6H5(CH2)nOH}(C6Me6)2(O)]+ (n=2,3)’ [J. Organomet. Chem. 684 (2003) 117–123]”, Journal of Organometallic Chemistry. Elsevier, p. 271. doi: 10.1016/j.jorganchem.2003.11.002.   edoc
Collot, J., Humbert, N., Skander, M., Klein, G. and Ward, T. R. (2004) “Artificial metalloenzymes for enantioselective catalysis : the phenomenon of protein accelerated catalysis”, Journal of Organometallic Chemistry. Elsevier, 689(25), pp. 4868–4871. doi: 10.1016/j.jorganchem.2004.09.032.   edoc
Suss-Fink, G., Therrien, B., Vieille-Petit, L., Tschan, M., Romakh, V. B., Ward, T. R., Dadras, M. and Laurenczy, G. (2004) “Supramolecular cluster catalysis: facts and problems”, Journal of Organometallic Chemistry. Elsevier, 689(8), pp. 1362–1369. doi: 10.1016/j.jorganchem.2003.12.032.   edoc
Skander, M., Humbert, N., Collot, J., Gradinaru, J., Klein, G., Loosli, A., Sauser, J., Zocchi, A., Gilardoni, F. and Ward, T. R. (2004) “Artificial Metalloenzymes:  (Strept)avidin as Host for Enantioselective Hydrogenation by Achiral Biotinylated Rhodium−Diphosphine Complexes”, Journal of the American Chemical Society. American Chemical Society, 126(44), pp. 14411–14418. doi: 10.1021/ja0476718.   edoc
Zocchi, A., Marya Jobe, A., Neuhaus, J.-M. and Ward, T. R. (2003) “Expression and purification of a recombinant avidin with a lowered isoelectric point in Pichia pastoris”, Protein Expression and Purification. Elsevier, 32(2), pp. 167–174. doi: 10.1016/j.pep.2003.09.001.   edoc
Vieille-Petit, L., Therrien, B., Suss-Fink, G. and Ward, T. R. (2003) “Isolation and single-crystal X-ray structure analysis of the catalyst–substrate host–guest complexes [C6H6⊂H3Ru3{C6H5(CH2)nOH}(C6Me6)2(O)]+ (n=2, 3)”, Journal of Organometallic Chemistry. Elsevier, 684(1/2), pp. 117–123. doi: 10.1016/S0022-328X(03)00519-9.   edoc
Collot, J., Gradinaru, J., Humbert, N., Skander, M., Zocchi, A. and Ward, T. R. (2003) “Artificial metalloenzymes for enantioselective catalysis based on biotin-avidin”, Journal of the American Chemical Society. American Chemical Society, 125(30), pp. 9030–9031. doi: 10.1021/ja035545i.   edoc
Zocchi, A., Humbert, N., Berta, T. and Ward, T. R. (2003) “Efficient expression and mutation of avidin and streptavidin as host proteins for enantioselective catalysis”, Chimia. Schweizerische Chemische Gesellschaft, 57(10), pp. 589–592. Available at: http://www.ingentaconnect.com/contentone/scs/chimia/2003/00000057/00000010/art00004.   edoc | Open Access
Ward, T. R., Collot, J., Gradinaru, J., Loosli, A., Skander, M., Letondor, C., Joseph, E. and Klein, G. (2003) “Exploiting the second coordination sphere : proteins as host for enantioselective catalysis”, Chimia. Schweizerische Chemische Gesellschaft, 57(10), pp. 586–588. Available at: http://www.ingentaconnect.com/contentone/scs/chimia/2003/00000057/00000010/art00003.   edoc | Open Access
Laurenczy, G., Faure, M., Vieille-Petit, L., Suss-Fink, G. and Ward, T. R. (2002) “Mechanistic in situ High-Pressure NMR Studies of Benzene Hydrogenation by Supramolecular Cluster Catalysis with [(η6-C6H6)(η6-C6Me6)2Ru3(μ3-O)(μ2-OH)(μ2-H)2][BF4]”, Advanced Synthesis and Catalysis. Wiley, 344(10), pp. 1073–1077. doi: 10.1002/1615-4169(200212)344:10<1073::AID-ADSC1073>3.0.CO;2-J .   edoc
Suss-Fink, G., Faure, M. and Ward, T. R. (2002) “Supramolecular Cluster Catalysis: Benzene Hydrogenation Catalyzed by a Cationic Triruthenium Cluster under Biphasic Conditions ”, Angewandte Chemie International Edition. Wiley, 41(1), pp. 99–101. doi: 10.1002/1521-3773(20020104)41:1<99::AID-ANIE99>3.0.CO;2-E .   edoc
Duclos, S., Stoeckli-Evans, H. and Ward, T. R. (2001) “Design and Synthesis of Compartmental Ligands and their Complexes for the Production of Catalytic Antibodies”, Helvetica Chimica Acta. Wiley, 84(10), pp. 3148–3161. doi: 10.1002/1522-2675(20011017)84:10<3148::AID-HLCA3148>3.0.CO;2-W .   edoc
Braendli, C. and Ward, T. R. (2000) “A Versatile Approach to the Solution-Phase Combinatorial Synthesis of Substituted Pyridines:  The Cobalt-Catalyzed Cyclotrimerization of Alkynes with a Nitrile”, Journal of Combinatorial Chemistry. American Chemical Society, 2(1), pp. 42–47. doi: 10.1021/cc9900450.   edoc
Therrien, B. and Ward, T. R. (1999) “Synthesis of a Configurationally Stable Three-Legged Piano-Stool Complex”, Angewandte Chemie International Edition. Wiley, 38(3), pp. 405–408. doi: 10.1002/(SICI)1521-3773(19990201)38:3<405::AID-ANIE405>3.0.CO;2-0.   edoc
Therrien, B., Koenig, A. and Ward, T. R. (1999) “Synthesis of a Configurationally Stable Three-Legged Piano-Stool Complex”, Organometallics. American Chemical Society, 18(8), pp. 1565–1568. doi: 10.1021/om980949i.   edoc
Ward, T. R., Lutz, A., Parel, S. P., Ensling, J., Guetlich, P., Buglyo, P. and Orvig, C. (1999) “An Iron-Based Molecular Redox Switch as a Model for Iron Release from Enterobactin via the Salicylate Binding Mode”, Inorganic Chemistry. American Chemical Society, 38(22), pp. 5007–5017. doi: 10.1021/ic990225e.   edoc
Ward, T. R. (1999) “From catalyst design to molecular devices : theory and experiments”., Chimia. Schweizerische Chemische Gesellschaft, 53(1/2), pp. 19–28. Available at: http://www.ingentaconnect.com/contentone/scs/chimia/1999/00000053/F0020001/art00006.   edoc | Open Access
Therrien, B., Ward, T. R., Pilkington, M., Hoffmann, C., Gilardoni, F. and Weber, J. (1998) “Synthesis and Reactivity of Tethered η1:η6-(Phosphinoarene)ruthenium Dichlorides”, Organometallics. American Chemical Society, 17(3), pp. 330–337. doi: 10.1021/om970735l.   edoc
Ward, T. R., Duclos, S., Therrien, B. and Schenk, K. (1998) “Coordination Properties of Klaeui’s Tripodal Oxygen Donor toward Zirconium(IV)”, Organometallics. American Chemical Society, 17(12), pp. 2490–2494. doi: 10.1021/om980088d.   edoc
Lutz, A. and Ward, T. R. (1998) “Tripodal dodecadentate ligands with salicylamide and bipyridine binding sites for iron(II) and iron(III) coordination”, Helvetica Chimica Acta. Wiley, 81(2), pp. 207–218. doi: 10.1002/hlca.19980810203.   edoc
Braendli, C. and Ward, T. R. (1998) “Libraries via Metathesis of Internal Olefins”, Helvetica Chimica Acta. Wiley, 81(9), pp. 1616–1621. doi: 10.1002/(SICI)1522-2675(19980909)81:9<1616::AID-HLCA1616>3.0.CO;2-P.   edoc
Gilardoni, F., Weber, J., Chermette, H. and Ward, T. R. (1998) “Reactivity Indices in Density Functional Theory:  A New Evaluation of the Condensed Fukui Function by Numerical Integration”, Journal of Physical Chemistry B. American Chemical Society, 102(20), pp. 3607–3613. doi: 10.1021/jp980521x.   edoc
Ward, T. R., Schafer, O., Daul, C. and Hofmann, P. (1997) “Geometry of Coordinatively Unsaturated Two-Legged Piano Stool Complexes with 16 Valence Electrons:  A Theoretical Study”, Organometallics. American Chemical Society, 16(14), pp. 3207–3215. doi: 10.1021/om9700369.   edoc
Ward, T. R., Buergi, H.-B., Gilardoni, F. and Weber, J. (1997) “Edge-Bridged Tetrahedral Geometry of Five-Coordinate d0 Complexes, Relatives of the Bent [MCp2L3] Family:  A Theoretical and Structure-Correlation Study”, Journal of the American Chemical Society. American Chemical Society, 119(49), pp. 11974–11985. doi: 10.1021/ja972230s.   edoc
Ward, T. R. (1997) “Electronic asymmetry : theoretical background, ligand design, and applications”, Chimia. Schweizerische Chemische Gesellschaft, 51(5), pp. 238–240. Available at: http://www.ingentaconnect.com/content/scs/chimia/1997/00000051/00000005/art00016.   edoc | Open Access
Ward, T. R. (1996) “Regioselectivity of Nucleophilic Attack on [Pd(allyl)(phosphine)(imine)] Complexes:  A Theoretical Study”, Organometallics. American Chemical Society, 15(12), pp. 2836–2838. doi: 10.1021/om960158l.   edoc
Lutz, A., Ward, T. R. and Albrecht, M. (1996) “Synthesis of salicylamide and bipyridine containing ligands for iron(II) and iron(III) coordination”, Tetrahedron. Elsevier, 52(37), pp. 12197–12208. doi: 10.1016/0040-4020(96)00724-7.   edoc
Giannini, L., Solari, E., De Angelis, S., Ward, T. R., Floriani, C., Chiesi-Villa, A. and Rizzoli, C. (1995) “Migratory aptitude of the Zr-C functionalities bonded to a macrocyclic structure : thermally- and solvent-assisted intra- and intermolecular migrations in dialkyl(dibenzotetramethyltetraazaannulene)zirconium(IV)”, Journal of the American Chemical Society. American Chemical Society, Vol. 117, H. 21, pp. 5801–5811.   edoc
Ward, T. R., Alemany, P. and Hoffmann, R. (1994) “Adhesion of Rh, Pd, and Pt to Alumina and NO Reactions on Resulting Surfaces”, ACS Symposium Series. American Chemical Society, 552, pp. 140–156. doi: 10.1021/bk-1994-0552.ch011.   edoc
Ward, T. R., Hoffmann, R. and Shelef, M. (1993) “Coupling nitrosyls as the first step in the reduction of NO on metal surfaces : the special role of rhodium”, Surface science. Elsevier, Vol. 289, H. 1/2, pp. 85–99.   edoc
Ward, T. R., Alemany, P. and Hoffmann, R. (1993) “Adhesion of rhodium, palladium, and platinum to alumina and the reduction of nitric oxide on the resulting surfaces: a theoretical analysis”, The Journal of physical chemistry. American Chemical Society, 97(29), pp. 7691–7699. doi: 10.1021/j100131a044.   edoc
Imhof, D., Rueegger, H., Venanzi, L. M. and Ward, T. R. (1991) “Solution structure of [(triphos*)RhH2(AuPPh3)3][PF6]2 deduced by one- and two-dimensional 1H{31P} and 1H{103Rh} double-resonance techniques”, Magnetic resonance in chemistry. John Wiley, Vol. 29, Spec. Issue, pp. 73–79.   edoc
Ward, T. R., Venanzi, L. M., Albinati, A., Lianza, F., Gerfin, T., Gramlich, V. and Ramos Tombo, G. M. (1991) “Synthesis and x-ray crystal structure of an optically pure tripodal C3-symmetric tritertiary phosphine bearing chirality on phosphorus”, Helvetica Chimica Acta. Helvetica Chimica Acta, Vol. 74, fasc. 5, pp. 983–988.   edoc
Ott, J., Schmid, B., Venanzi, L. M., Wang, G., Ward, T. R. and Tombo, G. M. R. (1990) “Rhodium Phosphine Complexes as Acetalization Catalysts”, New Journal of Chemistry. Royal Society of Chemistry, 14(6-7), pp. 495–498.   edoc
Ott, J., Ramos Tombo, G. M., Schmid, B., Venanzi, L. M., Wang, G. and Ward, T. R. (1989) “A versatile rhodium catalyst for acetalization reactions under mild conditions”, Tetrahedron Letters. Elsevier, 30(45), pp. 6151–6154. doi: 10.1016/S0040-4039(01)93328-3.   edoc
Cornioley-Deuschel, C., Ward, T. R. and Von Zelewsky, A. (1988) “Complexes with pincers : 2,6-Diphenylpyridine as twofold-deprotonated terdentate ligand in C,C-trans-, and as mono-deprotonated chelate ligand in chiral C,C-cis-complexes of platinum(II) and palladium(II)”, Helvetica Chimica Acta. Wiley, 71(1), pp. 130–133. doi: 10.1002/hlca.19880710116.   edoc