Publications

Mahmoud, A. B., Mäser, P., Kaiser, M., Hamburger, M. and Khalid, S. (2020) “Mining sudanese medicinal plants for antiprotozoal agents”, Frontiers in pharmacology. Frontiers Media, 11, p. 865. doi: 10.3389/fphar.2020.00865.   edoc | Open Access
Mahmoud, A. B., Danton, O., Kaiser, M., Han, S., Moreno, A., Abd Algaffar, S., Khalid, S., Oh, W. K., Hamburger, M. and Mäser, P. (2020) “Lignans, amides, and saponins from Haplophyllum tuberculatum and their antiprotozoal activity”, Molecules. MDPI, 25(12), p. 2825. doi: 10.3390/molecules25122825.   edoc | Open Access
Kaiser, M. and Mäser, P. (2020) In Vitro drug efficacy testing against Trypanosoma brucei. Edited by P. Michels, M. Ginger, and D. Zilberstein. New York: Springer. doi: 10.1007/978-1-0716-0294-2_46.   edoc
Wiedemar, N., Hauser, D. A. and Mäser, P. (2020) “100 years of Suramin”, Antimicrobial agents and chemotherapy. American Society for Microbiology, 64(3), pp. e01168–19. doi: 10.1128/AAC.01168-19.   edoc
Rao, S. P. S., Lakshminarayana, S. B., Jiricek, J., Kaiser, M., Ritchie, R., Myburgh, E., Supek, F., Tuntland, T., Nagle, A., Molteni, V., Mäser, P., Mottram, J. C., Barrett, M. P. and Diagana, T. T. (2020) “Anti-trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of african trypanosomiasis”, Tropical medicine and infectious disease. Multidisciplinary Digital Publishing Institute, 5, p. 28. doi: 10.3390/tropicalmed5010028.   edoc | Open Access
Dawidowski, M., Kalel, V. C., Napolitano, V., Fino, R., Schorpp, K., Emmanouilidis, L., Lenhart, D., Ostertag, M., Kaiser, M., Kolonko, M., Tippler, B., Schliebs, W., Dubin, G., Mäser, P., Tetko, I. V., Hadian, K., Plettenburg, O., Erdmann, R., Sattler, M. and Popowicz, G. M. (2020) “Structure-activity relationship in pyrazolo[4,3-c]pyridines, first inhibitors of PEX14-PEX5 protein-protein interaction with trypanocidal activity”, Journal of medicinal chemistry. American Chemical Society, 63(2), pp. 847–879. doi: 10.1021/acs.jmedchem.9b01876.   edoc
Vahekeni, N., Neto, P. M., Kayimbo, M. K., Mäser, P., Josenando, T., da Costa, E., Falquet, J. and Van Eeuwijk, P. (2020) “Use of herbal remedies in the management of sleeping sickness in four northern provinces of Angola”, Journal of Ethnopharmacology. Elsevier, p. 20.   edoc
Mahmoud, A. B., Mäser, P., Kaiser, M., Hamburger, M. and Khalid, S. A. (2020) “Mining Sudanese medicinal plants for antiprotozoal agents”, Front. Pharmacol, 11, p. 865. doi: 10.3389/fphar.2020.00865.   
Mahmoud, A. B., Danton, O., Kaiser, M., Han, S., Moreno, A., Algaffar, S. A., Khalid, S., Oh, W. K., Hamburger, M. and Mäser, P. (2020) “Lignans, amides, and saponins from the roots of Haplophyllum tuberculatum and their antiprotozoal activity”, Molecules, 25, p. 2825. doi: 10.3390/molecules25122825.   
Mahmoud, A. B., Danton, O., Kaiser, M., Khalid, S. A., Hamburger, M. and Mäser, P. (2020) “HPLC-based activity profiling for antiprotozoal compounds in Croton zambesicus and Cuscuta hyalina”, Front. Pharmacol, 11, p. 1246.   
Fesser, A. F., Braissant, O., Olmo, F., Kelly, J. M., Mäser, P. and Kaiser, M. (2020) “Non-invasive monitoring of drug action: a new live in vitro assay design for Chagas’ disease drug discovery”, PLoS neglected tropical diseases, 14(7), p. e0008487. doi: 10.1371/journal.pntd.0008487.   
Mahmoud, A. B., Danton, O., Kaiser, M., Khalid, S., Hamburger, M. and Mäser, P. (2020) “HPLC-based activity profiling for antiprotozoal compounds in Croton gratissimus and Cuscuta hyalina”, Frontiers in pharmacology, 11, p. 1246. doi: 10.3389/fphar.2020.01246.   
Jourdan, J., Walz, A., Matile, H., Schmidt, A., Wu, J., Wang, X., Dong, Y., Vennerstrom, J. L., Schmidt, R. S., Wittlin, S. and Mäser, P. (2019) “Stochastic Protein Alkylation by Antimalarial Peroxides”, ACS infectious diseases, 5(12), pp. 2067–2075. doi: 10.1021/acsinfecdis.9b00264.   edoc
Wiedemar, N., Zwyer, M., Zoltner, M., Cal, M., Field, M. C. and Mäser, P. (2019) “Expression of a specific variant surface glycoprotein has a major impact on suramin sensitivity and endocytosis in Trypanosoma brucei”, FASEB bioAdvances. Wiley , 1(10), pp. 595–608. doi: 10.1096/fba.2019-00033.   edoc | Open Access
Jourdan, J., Walz, A., Matile, H., Schmidt, A., Wu, J., Wang, X., Dong, Y., Vennerstrom, J. L., Schmidt, R. S., Wittlin, S. and Mäser, P. (2019) “Stochastic protein alkylation by antimalarial peroxides”, ACS infectious diseases. ACS Publications, 5(12), pp. 2067–2075. doi: 10.1021/acsinfecdis.9b00264.   edoc
Walz, A., Leroy, D., Andenmatten, N., Mäser, P. and Wittlin, S. (2019) “Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay”, Malaria journal. BioMed Central, 18, p. 427. doi: 10.1186/s12936-019-3056-8.   edoc | Open Access
Vu Van , T., Pham-Duc , P., Winkler, M. S., Zurbrügg, C., Zinsstag, J., Tran, B. H. and Nguyen-Viet , H. (2019) “New derivatives of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities”, Monatshefte für Chemie. Springer, 150(11), pp. 1959–1972. doi: 10.1007/s00706-019-02509-0.   edoc
Mäser, P. (2019) “Parasiten machen Geschichte”, in Bregy, C., Buschle, M., and Settelen-Trees, D. (eds.) Gespräche im Garten: Kultur - Natur - Gutes Leben: Tusculum auf Mapprach. Basel: Christoph Merian Verlag, pp. 127–131.   edoc
Hochegger, P., Faist, J., Seebacher, W., Saf, R., Mäser, P., Kaiser, M. and Weis, R. (2019) “Antiprotozoal activities of tetrazole-quinolines with aminopiperidine linker”, Medicinal chemistry (Shariqah (United Arab Emirates)). Bentham Sc. Publ. , 15(4), pp. 409–416. doi: 10.2174/1573406414666181015115101.   edoc
Mohsin, N. U. A., Seebacher, W., Hochegger, P., Faist, J., Saf, R., Kaiser, M., Mäser, P. and Weis, R. (2019) “Synthesis of new 1-benzyl tetrahydropyridin-4-ylidene piperidinium salts and their antiplasmodial and antitrypanosomal activities”, Medicinal chemistry research. Cambridge, Mass, 28(5), pp. 742–753. doi: 10.1007/s00044-019-02331-7.   edoc
Baragaña, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E., Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O’Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F.-J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. and Gilbert, I. H. (2019) “Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis”, Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 116(14), pp. 7015–7020. doi: 10.1073/pnas.1814685116.   edoc | Open Access
Hochegger, P., Faist, J., Seebacher, W., Saf, R., Mäser, P., Kaiser, M. and Weis, R. (2019) “Synthesis and structure-activity relationships for new 6-fluoroquinoline derivatives with antiplasmodial activity”, Bioorganic & medicinal chemistry. Pergamon, 27(10), pp. 2052–2065. doi: 10.1016/j.bmc.2019.03.061.   edoc
Rao, S. P. S., Barrett, M. P., Dranoff, G., Faraday, C. J., Gimpelewicz, C. R., Hailu, A., Jones, C. L., Kelly, J. M., Lazdins-Helds, J. K., Mäser, P., Mengel, J., Mottram, J. C., Mowbray, C. E., Sacks, D. L., Scott, P., Späth, G. F., Tarleton, R. L., Spector, J. M. and Diagana, T. T. (2019) “Drug discovery for kinetoplastid diseases : future directions”, ACS infectious diseases. ACS Publications, 5(2), pp. 152–157. doi: 10.1021/acsinfecdis.8b00298.   edoc
Saccoliti, F., Madia, V. N., Tudino, V., De Leo, A., Pescatori, L., Messore, A., De Vita, D., Scipione, L., Brun, R., Kaiser, M., Mäser, P., Calvet Alvarez, C. M., Jennings, G. K., Podust, L. M., Pepe, G., Cirilli, R., Faggi, C., Di Marco, A., Battista, M. R., Summa, V., Costi, R. and Di Santo, R. (2019) “Design, synthesis, and biological evaluation of new 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives as antiprotozoal agents”, Journal of Medicinal Chemistry. American Chemical Society, 62(3), pp. 1330–1347. doi: 10.1021/acs.jmedchem.8b01464.   edoc
Saccoliti, F., Madia, V. N., Tudino, V., De Leo, A., Pescatori, L., Messore, A., De Vita, D., Scipione, L., Brun, R., Kaiser, M., Mäser, P., Calvet, C. M., Jennings, G. K., Podust, L. M., Costi, R. and Di Santo, R. (2018) “Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents”, European journal of medicinal chemistry. Elsevier, 156, pp. 53–60. doi: 10.1016/j.ejmech.2018.06.063.   edoc
Gysin, M., Braissant, O., Gillingwater, K., Brun, R., Mäser, P. and Wenzler, T. (2018) “Isothermal microcalorimetry - a quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time”, International journal for parasitology. Drugs and drug resistance. Elsevier, 8(2), pp. 159–164. doi: 10.1016/j.ijpddr.2018.03.003.   edoc | Open Access
Schmidt, R. S., Macêdo, J. P., Steinmann, M. E., Salgado, A. G., Bütikofer, P., Sigel, E., Rentsch, D. and Mäser, P. (2018) “Transporters of Trypanosoma brucei : phylogeny, physiology, pharmacology”, The FEBS journal. Blackwell, 285(6), pp. 1012–1023. doi: 10.1111/febs.14302.   edoc
Oufir, M. G., K. Hamburger, M. R., I. Brun, R. M. and P. Wenzler, T. (2018) “Pharmacokinetic profiles reconcile in vitro and in vivo activities of novel trypanocidal compounds”, Matters. Sciencematters AG , p. 7000009. doi: 10.19185/matters.201807000009.   edoc | Open Access
Mäser, P. (2018) “Host-microbe interactions: Parasitology Vol 46”, Current opinion in microbiology. Current Biology, 46, pp. 6–8. doi: 10.1016/j.mib.2018.11.008.   edoc
Kalel, V. C., Mäser, P., Sattler, M., Erdmann, R. and Popowicz, G. M. (2018) “Come, sweet death : targeting glycosomal protein import for antitrypanosomal drug development”, Current Opinion in Microbiology. Elsevier, 46, pp. 116–122. doi: 10.1016/j.mib.2018.11.003.   edoc
Grogg, M. ., Hilvert, D., Ebert, M.-O. ., Beck, A. K., Seebach, D., Kurth, F., Dittrich, P. S., Sparr, C., Wittlin, S., Rottmann, M. and Mäser, P. (2018) “Cell penetration, herbicidal activity, and in-vivo-toxicity of oligo-arginine derivatives and of novel guanidinium-rich compounds derived from the biopolymer cyanophycin Grogg, Marcel and Hilvert, Donald and Ebert, Marc-Olivier and Beck, Albert K. and Seebach, Dieter and Kurth, Felix and Dittrich, Petra S. and Sparr, C. and Wittlin, Sergio and Rottmann, Matthias and Mäser, Pascal”, Helvetica Chimica Acta. Wiley, 101(10), p. e1800112. doi: 10.1002/hlca.201800112.   edoc | Open Access
Mohsin, N. U. A., Seebacher, W., Faist, J., Kretschmer, N., Bauer, R., Saf, R., Kaiser, M., Mäser, P. and Weis, R. (2018) “Modifications on tetrahydropyridin-4-ylidene ammonium salts and their antiprotozoal activities”, Monatshefte für Chemie. Springer, 149(4), pp. 801–812.   edoc
Subramaniam, S., Schmid, C. D., Guan, X. L. and Mäser, P. (2018) “Using yeast synthetic lethality to inform drug combination for Malaria”, Antimicrobial Agents and Chemotherapy. American Society for Microbiology, 62(4), pp. e01533–17. doi: 10.1128/AAC.01533-17.   edoc | Open Access
Mohsin, N. U. A., Seebacher, W., Faist, J., Hochegger, P., Kaiser, M., Mäser, P., Saf, R. and Weis, R. (2018) “The antiplasmodial and antitrypanosomal activities of novel piperazine derivatives of 3-azabicyclo[3.2.2]nonanes”, Monatshefte für Chemie. Springer, 149(1), pp. 99–109.   edoc
Wiedemar, N., Graf, F. E., Zwyer, M., Ndomba, E., Kunz Renggli, C., Cal, M., Schmidt, R. S., Wenzler, T. and Mäser, P. (2018) “Beyond immune escape: a variant surface glycoprotein causes suramin resistance in Trypanosoma brucei”, Molecular Microbiology. Blackwell, 107(1), pp. 57–67. doi: 10.1111/mmi.13854.   edoc | Open Access
Guan, X. L. and Mäser, P. (2017) “Comparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries”, Scientific reports. Springer Nature, 7, p. 13617. doi: 10.1038/s41598-017-13931-x.   edoc
Steinmann, M. E., Schmidt, R. S., Macêdo, J. P., Kunz Renggli, C., Bütikofer, P., Rentsch, D., Mäser, P. and Sigel, E. (2017) “Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei”, PLoS ONE. Public Library of Science, 12(12), p. e0188219. doi: 10.1371/journal.pone.0188219.   edoc
Mäser, P. (2017) “Cherchez l’electron”, Molecular microbiology. Blackwell, 106(2), pp. 183–185.   edoc
Mohsin, N.-U.-A., Seebacher, W., Faist, J., Hochegger, P., Kaiser, M., Mäser, P., Belaj, F., Saf, R., Kretschmer, N., Alajlani, M., Turek, I., Brantner, A., Bauer, R., Bucar, F. and Weis, R. (2017) “Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities”, European journal of medicinal chemistry. Elsevier, 143, pp. 97–106. doi: 10.1016/j.ejmech.2017.11.025.   edoc
Hochegger, P., Faist, J., Seebacher, W., Saf, R., Mäser, P., Kaiser, M. and Weis, R. (2017) “New derivatives of quinoline-4-carboxylic acid with antiplasmodial activity”, Bioorganic & medicinal chemistry. Pergamon, 25(7), pp. 2251–2259. doi: 10.1016/j.bmc.2017.02.043.   edoc
Seebacher, W., Belaj, F., Faist, J., Saf, R., Bucar, F., Turek, I., Branter, A., Alajlani, M., Kaiser, M., Mäser, P. and Weis, R. (2017) “Synthesis of new pyrido-benzodiazepine salts and their antimicrobial activities”, Monatshefte für Chemie. Springer, 148(2), pp. 263–274. doi: 10.1007/s00706-016-1864-x.   edoc
Steinmann, M. E., Schmidt, R. S., Bütikofer, P., Mäser, P. and Sigel, E. (2017) “TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes”, Scientific Reports. Nature Publishing Group, 7(1), p. 656. doi: 10.1038/s41598-017-00752-1.   edoc
Jeacock, L., Baker, N., Wiedemar, N., Mäser, P. and Horn, D. (2017) “Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity”, PLoS Pathogens. Public Library of Science, 13(3), p. e1006307. doi: 10.1371/journal.ppat.1006307.   edoc
Dawidowski, M., Emmanouilidis, L., Kalel, V. C., Tripsianes, K., Schorpp, K., Hadian, K., Kaiser, M., Mäser, P., Kolonko, M., Tanghe, S., Rodriguez, A., Schliebs, W., Erdmann, R., Sattler, M. and Popowicz, G. M. (2017) “Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites”, Science. American Association for the Advancement of Science, 355(6332), pp. 1416–1420. doi: 10.1126/science.aal1807.   edoc
Baumgärtner, F., Jourdan, J., Scheurer, C., Blasco, B., Campo, B., Mäser, P. and Wittlin, S. (2017) “In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate”, Malaria journal. BioMed Central, 16, p. 45. doi: 10.1186/s12936-017-1696-0.   edoc | Open Access
Faist, J., Hinteregger, C., Seebacher, W., Saf, R., Mäser, P., Kaiser, M. and Weis, R. (2017) “New derivatives of 7-chloroquinolin-4-amine with antiprotozoal activity”, Bioorganic & medicinal chemistry. Pergamon, 25(3), pp. 941–948. doi: 10.1016/j.bmc.2016.12.006.   edoc
Mathieu, C., Macêdo, J. P., Hürlimann, D., Wirdnam, C., Haindrich, A. C., Suter Grotemeyer, M., González-Salgado, A., Schmidt, R. S., Inbar, E., Mäser, P., Bütikofer, P., Zilberstein, D. and Rentsch, D. (2017) “Arginine and lysine transporters are essential for Trypanosoma brucei”, PLoS ONE. Public Library of Science, 12, p. e0168775. doi: 10.1371/journal.pone.0168775.   edoc | Open Access
Graf, F. E., Ludin, P., Arquint, C., Schmidt, R. S., Schaub, N., Kunz Renggli, C., Munday, J. C., Krezdorn, J., Baker, N., Horn, D., Balmer, O., Caccone, A., de Koning, H. P. and Mäser, P. (2016) “Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense”, Cellular and molecular life sciences. Birkhäuser, 73(17), pp. 3387–3400. doi: 10.1007/s00018-016-2173-6.   edoc
Wang, T., Mäser, P. and Picard, D. (2016) “Inhibition of Plasmodium falciparum Hsp90 contributes to the antimalarial activities of aminoalcohol-carbazoles”, Journal of Medicinal Chemistry. American Chemical Society, 59(13), pp. 6344–6352. doi: 10.1021/acs.jmedchem.6b00591.   edoc | Open Access
Wenzler, T., Schumann Burkard, G., S. Schmidt, R., Mäser, P., Bergner, A., Roditi, I. and Brun, R. (2016) “A new approach to chemotherapy : drug-induced differentiation kills African trypanosomes”, Scientific Reports. Nature Publishing Group, 6, p. 22451. doi: 10.1038/srep22451.   edoc
Jourdan, J., Hugues, M., Reift, E., Biehlmaier, O., Dong, Y., Wang, X., Mäser, P., Vennerstrom, J. and Wittlin, S. (2016) “Monoclonal antibodies that recognize the alkylation signature of antimalarial ozonides OZ277 (Arterolane) and OZ439 ( Artefenomel)”, ACS infectious diseases. ACS Publications, 2(1), pp. 54–61. doi: 10.1021/acsinfecdis.5b00090.   edoc
Steinmann, M. E., González-Salgado, A., Bütikofer, P., Mäser, P. and Sigel, E. (2015) “A heteromeric potassium channel involved in the modulation of the plasma membrane potential is essential for the survival of African trypanosomes”, The FASEB journal. FASEB], Vol. 29, H. 8, pp. 3228–3237. doi: 10.1096/fj.15-271353.   edoc
Kaiser, M., Mäser, P., Tadoori, L. P., Ioset, J.-R. and Brun, R. (2015) “Antiprotozoal activity profiling of approved drugs : a starting point toward drug repositioning”, PLoS ONE. Public Library of Science, Vol. 10, H. 8 , e0135556. doi: 10.1371/journal.pone.0135556.   edoc | Open Access
Graf, F. E., Baker, N., Munday, J. C., de Koning, H. P., Horn, D. and Mäser, P. (2015) “Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates”, International journal for parasitology. Drugs and drug resistance. Elsevier], Vol. 5, H. 2, pp. 65–68. doi: 10.1016/j.ijpddr.2015.04.002.   edoc
Witschel, M. C., Rottmann, M., Schwab, A., Leartsakulpanich, U., Chitnumsub, P., Seet, M., Tonazzi, S., Schwertz, G., Stelzer, F., Mietzner, T., McNamara, C., Thater, F., Freymond, C., Jaruwat, A., Pinthong, C., Riangrungroj, P., Oufir, M., Hamburger, M., Mäser, P., Sanz-Alonso, L. M., Charman, S., Wittlin, S., Yuthavong, Y., Chaiyen, P. and Diederich, F. (2015) “Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT) : co-crystal structures of pyrazolopyrans with potent blood-and liver-stage activities”, Journal of Medicinal Chemistry. American Chemical Society, 58(7), pp. 3117–3130. doi: 10.1021/jm501987h.   edoc
de Macêdo, J. P., Schumann Burkard, G., Niemann, M., Barrett, M. P., Vial, H., Mäser, P., Roditi, I., Schneider, A. and Bütikofer, P. (2015) “An atypical mitochondrial carrier that mediates drug action in Trypanosoma brucei”, PLoS Pathogens. Public Library of Science, Vol. 11, H. 5 , e1004875. doi: 10.1371/journal.ppat.1004875.   edoc | Open Access
Shameer, S., Logan-Klumpler, F. J., Vinson, F., Cottret, L., Merlet, B., Achcar, F., Boshart, M., Berriman, M., Breitling, R., Bringaud, F., Bütikofer, P., Cattanach, A. M., Bannerman-Chukualim, B., Creek, D. J., Crouch, K., de Koning, H. P., Denise, H., Ebikeme, C., Fairlamb, A. H., Ferguson, M. A. J., Ginger, M. L., Hertz-Fowler, C., Kerkhoven, E. J., Mäser, P., Michels, P. A. M., Nayak, A., Nes, D. W., Nolan, D. P., Olsen, C., Silva-Franco, F., Smith, T. K., Taylor, M. C., Tielens, A. G. M., Urbaniak, M. D., van Hellemond, J. J., Vincent, I. M., Wilkinson, S. R., Wyllie, S., Opperdoes, F. R., Barrett, M. P. and Jourdan, F. (2015) “TrypanoCyc : a community-led biochemical pathways database for Trypanosoma brucei”, Nucleic Acids Research. Oxford University Press, 43(D1), pp. D637-D644. doi: 10.1093/nar/gku944.   edoc | Open Access
Fügi, M. A., Kaiser, M., Tanner, M., Schneiter, R., Mäser, P. and Guan, X. L. (2014) “Match-making for posaconazole through systems thinking”, Trends in parasitology. Elsevier, pp. 46–51. doi: 10.1016/j.pt.2014.11.004.   edoc
Sistrom, M., Evans, B., Bjornson, R., Gibson, W., Balmer, O., Mäser, P., Aksoy, S. and Caccone, A. (2014) “Comparative genomics reveals multiple genetic backgrounds of human pathogenicity in the Trypanosoma brucei complex”, Genome biology and evolution. Oxford University Press, Vol. 6, H. 10, pp. 2811–2819. doi: 10.1093/gbe/evu222.   edoc
Mathieu, C., Salgado, A. G., Wirdnam, C., Meier, S., Grotemeyer, M. S., Inbar, E., Mäser, P., Zilberstein, D., Sigel, E., Bütikofer, P. and Rentsch, D. (2014) “Trypanosoma brucei eflornithine transporter AAT6 is a low-affinity low-selective transporter for neutral amino acids”, Biochemical journal. Portland Press, Vol. 463, Pt. 1, pp. 9–18. doi: 10.1042/BJ20140719.   edoc
Fügi, M. A., Gunasekera, K., Ochsenreiter, T., Guan, X., Wenk, M. R. and Mäser, P. (2014) “Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack”, Journal of Lipid Research. American Society for Biochemistry and Molecular Biology, 55(5), pp. 929–938. doi: 10.1194/jlr.M048017.   edoc | Open Access
Munday, J. C., Eze, A. A., Baker, N., Glover, L., Clucas, C., Aguinaga Andrés, D., Natto, M. J., Teka, I. A., McDonald, J., Lee, R. S., Graf, F. E., Ludin, P., Burchmore, R. J. S., Turner, C. M. R., Tait, A., MacLeod, A., Mäser, P., Barrett, M. P., Horn, D. and De Koning, H. P. (2014) “Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs”, The journal of antimicrobial chemotherapy. Academic Press, Vol. 69, H. 3, pp. 651–663. doi: 10.1093/jac/dkt442.   edoc
Wang, T., Bisson, W. H., Mäser, P., Scapozza, L. and Picard, D. (2014) “Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors”, Journal of medicinal chemistry. American Chemical Society, 57(6), pp. 2524–2535. doi: 10.1021/jm401801t.   edoc
Lüscher, A., Lamprea-Burgunder, E., Graf, F. E., de Koning, H. P. and Mäser, P. (2014) “Trypanosoma brucei adenine-phosphoribosyltransferases mediate adenine salvage and aminopurinol susceptibility but not adenine toxicity”, International journal for parasitology : drugs and drug resistance. Elsevier], Vol. 4, H. 1, pp. 55–63. doi: 10.1016/j.ijpddr.2013.12.001.   edoc
Macêdo, J. P., Schmidt, R. S., Mäser, P., Rentsch, D., Vial, H. J., Sigel, E. and Bütikofer, P. (2013) “Characterization of choline uptake in Trypanosoma brucei procyclic and bloodstream forms”, Molecular & biochemical parasitology. Elsevier, Vol. 190, H. 1, pp. 16–22. doi: 10.1016/j.molbiopara.2013.05.007.   edoc
Greganova, E., Steinmann, M., Mäser, P. and Fankhauser, N. (2013) “In silico ionomics segregates parasitic from free-living eukaryotes”, Genome biology and evolution. Oxford University Press, Vol. 5, H. 10, pp. 1902–1909. doi: 10.1093/gbe/evt134.   edoc
Graf, F. E., Ludin, P., Wenzler, T., Kaiser, M., Brun, R., Pyana, P. P., Büscher, P., de Koning, H. P., Horn, D. and Mäser, P. (2013) “Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol”, PLoS neglected tropical diseases. Public Library of Science, Vol. 7, H. 10 , e2475. doi: 10.1371/journal.pntd.0002475.   edoc | Open Access
Baker, N., de Koning, H. P., Mäser, P. and Horn, D. (2013) “Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story”, Trends in parasitology. Elsevier, Vol. 29, H. 3, pp. 110–118. doi: 10.1016/j.pt.2012.12.005.   edoc
Ali, J. A. M., Creek, D. J., Burgess, K., Allison, H. C., Field, M. C., Mäser, P. and de Koning, H. P. (2013) “Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines”, Molecular pharmacology : an international journal. Academic Press, Vol. 83, H. 2, pp. 439–453. doi: 10.1124/mol.112.082321.   edoc
Oehring, S. C., Woodcroft, B. J., Moes, S., Wetzel, J., Dietz, O., Pulfer, A., Dekiwadia, C., Maeser, P., Flueck, C., Witmer, K., Brancucci, N. M., Niederwieser, I., Jenoe, P., Ralph, S. A. and Voss, T. S. (2012) “Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum”, Genome biology. BioMed Central, Vol. 13, H. 11 , R108. doi: 10.1186/gb-2012-13-11-r108.   edoc
Godel, C., Kumar, S., Koutsovoulos, G., Ludin, P., Nilsson, D., Comandatore, F., Wrobel, N., Thompson, M., Schmid, C. D., Goto, S., Bringaud, F., Wolstenholme, A., Bandi, C., Epe, C., Kaminsky, R., Blaxter, M. and Mäser, P. (2012) “The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets”, The FASEB Journal : official publication of the Federation of American Societies for Experimental Biology. FASEB, Vol. 26, H. 11, pp. 4650–4661. doi: 10.1096/fj.12-205096.   edoc
Gonzalez-Salgado, A., Steinmann, M. E., Greganova, E., Rauch, M., Mäser, P., Sigel, E. and Bütikofer, P. (2012) “myo-inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei”, Journal of biological chemistry. American Society of Biological Chemists, Vol. 287, H. 16, pp. 13313–13323. doi: 10.1074/jbc.M112.344812.   edoc
Ludin, P., Woodcroft, B., Ralph, S. A. and Maeser, P. (2012) “In silicio prediction of antimalarial drug target candidates”, International journal for parasitology: drugs and drug resistance. Elsevier, Vol. 2, pp. 191–199. doi: 10.1016/j.ijpddr.2012.07.002.   edoc
Mäser, P., Wittlin, S., Rottmann, M., Wenzler, T., Kaiser, M. and Brun, R. (2012) “Antiparasitic agents : new drugs on the horizon”, Current opinion in pharmacology. Elsevier, Vol. 12, H. 5, pp. 562–566. doi: 10.1016/j.coph.2012.05.001.   edoc
Ludin, P., Nilsson, D. and Mäser, P. (2011) “Genome-wide identification of molecular mimicry candidates in parasites”, PLoS ONE. Public Library of Science, 6(3), p. e17546. doi: 10.1371/journal.pone.0017546.   edoc
Lamprea-Burgunder, E., Ludin, P. and Mäser, P. (2011) “Species-specific typing of DNA based on palindrome frequency patterns”, DNA research. Oxford University Press, 18(2), pp. 117–124. doi: 10.1093/dnares/dsr004.   edoc
Teka, I. A., Kazibwe, A. J. N., El-Sabbagh N., Al-Salabi M. I., Ward, C. P., Eze, A. A., Munday, J. C., Mäser, P., Matovu, E., Barrett, M. P. and de Koning H. P. (2011) “The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes”, Molecular pharmacology : an international journal. Academic Press, Vol. 80, H. 1, pp. 110–116. doi: 10.1124/mol.111.071555.   edoc
Nerima, B., Nilsson, D. and Mäser, P. (2010) “Comparative genomics of metabolic networks of free-living and parasitic eukaryotes”, BMC Genomics. BioMed Central, Vol. 11 , 217.   edoc
Rufener, L., Baur, R., Kaminsky, R., Mäser, P. and Sigel, E. (2010) “Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus”, Molecular pharmacology : an international journal. Academic Press, Vol. 78, H. 5, pp. 895–902.   edoc
Mosimann, M., Goshima, S., Wenzler, T., Luscher, A., Uozumi, N. and Mäser, P. (2010) “A Trk/HKT-type K+ transporter from Trypanosoma brucei”, Eukaryotic Cell. American Society for Microbiology, Vol. 9, H. 4, pp. 539–546.   edoc
Rufener, L., Keiser, J., Kaminsky, R., Mäser, P. and Nilsson, D. (2010) “Phylogenomics of ligand-gated ion channels predicts monepantel effect”, PLoS Pathogens. Public Library of Science, Vol. 6, H. 9 , e1001091.   edoc
Kuettel, S., Mosimann, M., Mäser, P., Kaiser, M., Brun, R., Scapozza, L. and Perozzo, R. (2009) “Adenosine kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics”, PLoS Neglected Tropical Diseases. Library of Science, Vol. 3, H. 8 , e506.   edoc
Bernhard, S. C., Nerima, B., Mäser, P. and Brun, R. (2007) “Melarsoprol- and pentamidine-resistant Trypanosoma brucei rhodesiense populations and their cross-resistance”, International journal for parasitology. Elsevier, Vol. 37, H. 13, pp. 1443–1448.   edoc
Maina, N., Maina, K. J., Mäser, P. and Brun, R. (2007) “Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate”, Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin = revue des sciences tropicales et de médecine tropicale = review of tropical science and tropical medicine. Elsevier Science Publ, 104(2-3), pp. 84–90.   edoc
Mäser, P., Grether-Bühler, Y., Kaminsky, R. and Brun, R. (2002) “An anti-contamination cocktail for the in vitro isolation and cultivation of parasitic protozoa”, Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie. Springer-Verlag, Vol. 88, H. 2, pp. 172–174.   edoc