Publications

Cianfanelli, F. R., Cunrath, O. and Bumann, D. (2020) “Efficient Dual-Negative Selection for Bacterial Genome Editing”. bioRxiv. doi: 10.1101/2020.03.03.974816.   edoc | Open Access
Wolf, T., Jin, W., Zoppi, G., Vogel, I. A., Akhmedov, M., Bleck, C. K. E., Beltraminelli, T., Rieckmann, J. C., Ramirez, N. J., Benevento, M., Notarbartolo, S., Bumann, D., Meissner, F., Grimbacher, B., Mann, M., Lanzavecchia, A., Sallusto, F., Kwee, I. and Geiger, R. (2020) “Dynamics in protein translation sustaining T cell preparedness”, Nature immunology. Nature Research, 21(8), pp. 927–937. doi: 10.1038/s41590-020-0714-5.   edoc
Roche, B. and Bumann, D. (2020) “Single-cell reporters for pathogen responses to antimicrobial host attacks”, Current opinion in microbiology. Elsevier, 59, pp. 16–23. doi: 10.1016/j.mib.2020.07.013.   edoc | Open Access
Mas, G., Burmann, B. M., Sharpe, T., Claudi, B., Bumann, D. and Hiller, S. (2020) “Regulation of chaperone function by coupled folding and oligomerization”, Science advances. American Association for the Advancement of Science , 6(43), p. eabc5822. doi: 10.1126/sciadv.abc5822.   edoc | Open Access
Rosas-Ballina, M., Guan, X. L., Schmidt, A. and Bumann, D. (2020) “Classical Activation of Macrophages Leads to Lipid Droplet Formation Without; de novo; Fatty Acid Synthesis”, Frontiers in Immunology. Frontiers Media, 11, p. 131. doi: 10.3389/fimmu.2020.00131.   edoc | Open Access
Hausmann, A., Böck, D., Geiser, P., Berthold, D. L., Fattinger, S. A., Furter, M., Bouman, J. A., Barthel-Scherrer, M., Lang, C. M., Bakkeren, E., Kolinko, I., Diard, M., Bumann, D., Slack, E., Regoes, R. R., Pilhofer, M., Sellin, M. E. and Hardt, W.-D. (2020) “Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression”, Mucosal Immunology. Nature, (13), pp. 530–544. doi: 10.1038/s41385-019-0247-0.   edoc | Open Access
Eren, E., Planes, R., Buyck, J., Bordignon, P.-J., Colom, A., Cunrath, O., Dreier, R. F., Santos, J. C., Duplan-Eche, V., Näser, E., Peixoto, A., Bumann, D., Cougoule, C., Coste, A., Neyrolles, O., Broz, P. and Meunier, E. (2019) “Type-3 Secretion System-induced pyroptosis protects Pseudomonas against cell-autonomous immunity”. bioRxiv. doi: 10.1101/650333.   edoc | Open Access
Balaban, N. Q., Helaine, S., Lewis, K., Ackermann, M., Aldridge, B., Andersson, D. I., Brynildsen, M. P., Bumann, D., Camilli, A., Collins, J. J., Dehio, C., Fortune, S. M., Ghigo, J.-M., Hardt, W.-D., Harms, A., Heinemann, M., Hung, D. T., Jenal, U., Levin, B. R., Michiels, J., Storz, G., Tan, M.-W., Tenson, T., Van Melderen, L. and Zinkernagel, A. (2019) “Definitions and guidelines for research on antibiotic persistence”, Nature Reviews Microbiology. Nature Publishing Group, 17(7), pp. 441–448. doi: 10.1038/s41579-019-0196-3.   edoc
Carballido Lopez, A., Cunrath, O., Forster, A., Pérard, J., Graulier, G., Legendre, R., Varet, H., Sismeiro, O., Perraud, Q., Pesset, B., Saint Auguste, P., Bumann, D., Mislin, G. L. A., Coppee, J. Y., Michaud-Soret, I., Fechter, P. and Schalk, I. J. (2019) “Non-specific interference of cobalt with siderophore-dependent iron uptake pathways”, Metallomics : integrated biometal science, 11(11), pp. 1937–1951. doi: 10.1039/c9mt00195f.   edoc
Bhamidimarri, S. P., Zahn, M., Prajapati, J. D., Schleberger, C., Söderholm, S., Hoover, J., West, J., Kleinekathöfer, U., Bumann, D., Winterhalter, M. and van den Berg, B. (2019) “A Multidisciplinary Approach toward Identification of Antibiotic Scaffolds for Acinetobacter baumannii”, Structure (London, England : 1993), 27(2), pp. 268–280.e6. doi: 10.1016/j.str.2018.10.021.   edoc
Bumann, D. (2019) “Salmonella; Single-Cell Metabolism and Stress Responses in Complex Host Tissues”, Microbiology spectrum, 7(2), pp. BAI–0009. doi: 10.1128/microbiolspec.BAI-0009-2019.   edoc
Bumann, D., Fanous, J., Li, J. and Goormaghtigh, F. (2019) “Antibiotic chemotherapy against heterogeneous pathogen populations in complex host tissues”, F1000Research. F1000Research, 8, p. 1781. doi: 10.12688/f1000research.19441.1.   edoc | Open Access
Cunrath, O. and Bumann, D. (2019) “Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation”, Science. American Association for the Advancement of Science, 366(6468), pp. 995–999. doi: 10.1126/science.aax7898.   edoc | Open Access
Trebosc, V., Gartenmann, S., Tötzl, M., Lucchini, V., Schellhorn, B., Pieren, M., Lociuro, S., Gitzinger, M., Tigges, M., Bumann, D. and Kemmer, C. (2019) “Dissecting Colistin Resistance Mechanisms in Extensively Drug-Resistant Acinetobacter baumannii Clinical Isolates”, mBio. American Society for Microbiology, 10(4), pp. e01083–19. doi: 10.1128/mBio.01083-19.   edoc | Open Access
Cunrath, O., Meinel, D. M., Maturana, P., Fanous, J., Buyck, J. M., Saint Auguste, P., Seth-Smith, H. M. B., Körner, J., Dehio, C., Trebosc, V., Kemmer, C., Neher, R., Egli, A. and Bumann, D. (2019) “Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains”, EBioMedicine. Elsevier, 41, pp. 479–487. doi: 10.1016/j.ebiom.2019.02.061.   edoc | Open Access
Jayachandran, R., Gumienny, A., Bolinger, B., Ruehl, S., Lang, M. J., Fucile, G., Mazumder, S., Tchang, V. S. Y., Woischnig, A.-K., Stiess, M., Kunz, G., Claudi, B., Schmaler, M., Siegmund, K., Li, J., Dertschnig, S., Hollaender, G., Medina, E., Karrer, U., Moshous, D., Bumann, D., Khanna, N., Rossi, S. W. and Pieters, J. (2019) “Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity”, Immunity. Cell Press, 50(1), pp. 152–165. doi: 10.1016/j.immuni.2018.12.011.   edoc | Open Access
Luscher, A., Moynié, L., Auguste, P. S., Bumann, D., Mazza, L., Pletzer, D., Naismith, J. H. and Köhler, T. (2018) “TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates”, Antimicrobial agents and chemotherapy, 62(6), pp. e00097–18. doi: 10.1128/AAC.00097-18.   edoc
Lim, D., Kim, K. S., Jeong, J.-H., Marques, O., Kim, H.-J., Song, M., Lee, T.-H., Kim, J. I., Choi, H.-S., Min, J.-J., Bumann, D., Muckenthaler, M. U. and Choy, H. E. (2018) “The hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages”, Nature communications, 9(1), p. 2091. doi: 10.1038/s41467-018-04446-8.   edoc
Samanta, S., Bodrenko, I., Acosta-Gutiérrez, S., D’Agostino, T., Pathania, M., Ghai, I., Schleberger, C., Bumann, D., Wagner, R., Winterhalter, M., van den Berg, B. and Ceccarelli, M. (2018) “Getting Drugs through Small Pores: Exploiting the Porins Pathway in Pseudomonas aeruginosa”, ACS infectious diseases, 4(10), pp. 1519–1528. doi: 10.1021/acsinfecdis.8b00149.   edoc
Napolitani, G., Kurupati, P., Teng, K. W. W., Gibani, M. M., Rei, M., Aulicino, A., Preciado-Llanes, L., Wong, M. T., Becht, E., Howson, L., de Haas, P., Salio, M., Blohmke, C. J., Olsen, L. R., Pinto, D. M. S., Scifo, L., Jones, C., Dobinson, H., Campbell, D., Juel, H. B., Thomaides-Brears, H., Pickard, D., Bumann, D., Baker, S., Dougan, G., Simmons, A., Gordon, M. A., Newell, E. W., Pollard, A. J. and Cerundolo, V. (2018) “Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses”, Nature immunology, 19(7), pp. 742–754. doi: 10.1038/s41590-018-0133-z.   edoc
Dehio, C. and Bumann, D. (2017) “Editorial overview: Bacterial systems biology”, Current Opinion in Microbiology, 39, p. viii-xi. doi: 10.1016/j.mib.2017.11.024.   edoc
Wu, A., Tymoszuk, P., Haschka, D., Heeke, S., Dichtl, S., Petzer, V., Seifert, M., Hilbe, R., Sopper, S., Talasz, H., Bumann, D., Lass-Flörl, C., Theurl, I., Zhang, K. and Weiss, G. (2017) “Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling”, Infection and Immunity, 85(12), pp. e00418–17. doi: 10.1128/IAI.00418-17.   edoc | Open Access
Abellón-Ruiz, J., Kaptan, S. S., Baslé, A., Claudi, B., Bumann, D., Kleinekathöfer, U. and van den Berg, B. (2017) “Structural basis for maintenance of bacterial outer membrane lipid asymmetry”, Nature Microbiology. Nature Publishing Group, 2(12), pp. 1616–1623. doi: 10.1038/s41564-017-0046-x.   edoc
Schürmann, N., Forrer, P., Casse, O., Li, J., Felmy, B., Burgener, A.-V., Ehrenfeuchter, N., Hardt, W.-D., Recher, M., Hess, C., Tschan-Plessl, A., Khanna, N. and Bumann, D. (2017) “Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage”, Nature Microbiology. Nature Publishing Group, 2, p. 16268. doi: 10.1038/nmicrobiol.2016.268.   edoc | Open Access
Bumann, D. and Schothorst, J. (2017) “Intracellular Salmonella metabolism”, Cellular Microbiology. Wiley, 19(10), p. e12766. doi: 10.1111/cmi.12766.   edoc | Open Access
Bumann, D. and Cunrath, O. (2017) “Heterogeneity of Salmonella-host interactions in infected host tissues”, Current Opinion in Microbiology. Elsevier, 39, pp. 57–63. doi: 10.1016/j.mib.2017.09.008.   edoc | Open Access
Gasser, V., Baco, E., Cunrath, O., Saint August, P., Perraud, Q., Zill, N., Schleberger, C., Schmidt, A., Paulen, A., Bumann, D., Mislin, G. L. A. and Schalk, I. J. (2016) “Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in Pseudomonas aeruginosa: an opportunity for siderophore-antibiotic conjugates development”, Environmental Microbiology. Wiley, 18(3), pp. 819–832. doi: 10.1111/1462-2920.13199.   edoc
Trebosc, V., Gartenmann, S., Royet, K., Manfredi, P., Tötzl, M., Schellhorn, B., Pieren, M., Tigges, M., Lociuro, S., Sennhenn, P. C., Gitzinger, M., Bumann, D. and Kemmer, C. (2016) “A novel genome editing platform for drug resistant Acinetobacter baumannii revealed an AdeR-unrelated tigecycline resistance mechanism”, Antimicrobial Agents and Chemotherapy. American Society for Microbiology, 60(12), pp. 7263–7271. doi: 10.1128/AAC.01275-16.   edoc
Freed, N. E., Bumann, D. and Silander, O. K. (2016) “Combining Shigella Tn-seq data with gold-standard E. coli gene deletion data suggests rare transitions between essential and non-essential gene functionality”, BMC Microbiology. BioMed Central, 16(1), p. 203. doi: 10.1186/s12866-016-0818-0.   edoc | Open Access
Abu Kwaik, Y. and Bumann, D. (2015) “Host delivery of favorite meals for intracellular pathogens”, PLoS Pathogens. Public Library of Science, Vol. 11, H. 6 , e1004866. doi: 10.1371/journal.ppat.1004866.   edoc | Open Access
Bumann, D. (2015) “Heterogeneous Host-Pathogen Encounters: Act Locally, Think Globally”, Cell Host & Microbe. Cell Press, pp. 13–19. doi: 10.1016/j.chom.2014.12.006.   edoc
McEwan, D. G., Richter, B., Claudi, B., Wigge, C., Wild, P., Farhan, H., McGourty, K., Coxon, F. P., Franz-Wachtel, M., Perdu, B., Akutsu, M., Habermann, A., Kirchof, A., Helfrich, M. H., Odgren, P. R., Van Hul, W., Frangakis, A. S., Rajalingam, K., Macek, B., Holden, D. W., Bumann, D. and Dikic, I. (2015) “PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection”, Cell Host & Microbe. Cell Press, 17(1), pp. 58–71. doi: 10.1016/j.chom.2014.11.011.   edoc
Martano, G., Delmotte, N., Kiefer, P., Christen, P., Kentner, D., Bumann, D. and Vorholt, J. A. (2015) “Fast sampling method for mammalian cell metabolic analyses using liquid chromatography-mass spectrometry”, Nature Protocols. Nature Publishing Group, 10(1), pp. 1–11. doi: 10.1038/nprot.2014.198.   edoc
Bumann, D. (2014) “Identification of protective antigens for vaccination against systemic salmonellosis”, Frontiers in Immunology. Frontiers Media, 5(381), pp. 1–5. doi: 10.3389/fimmu.2014.00381.   edoc | Open Access
Kentner, D., Martano, G., Callon, M., Chiquet, P., Brodmann, M., Burton, O., Wahlander, A., Nanni, P., Delmotte, N., Grossmann, J., Limenitakis, J., Schlapbach, R., Kiefer, P., Vorholt, J. A., Hiller, S. and Bumann, D. (2014) “Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth”, Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 111(27), pp. 9929–9934. doi: 10.1073/pnas.1406694111.   edoc
Claudi, B., Spröte, P., Chirkova, A., Personnic, N., Zankl, J., Schürmann, N., Schmidt, A. and Bumann, D. (2014) “Phenotypic variation of salmonella in host tissues delays eradication by antimicrobial chemotherapy”, Cell. Cell Press, 158(4), pp. 722–733. doi: 10.1016/j.cell.2014.06.045.   edoc
Meunier, E., Dick, M. S., Dreier, R. F., Schürmann, N., Kenzelmann Broz, D., Warming, S., Roose-Girma, M., Bumann, D., Kayagaki, N., Takeda, K., Yamamoto, M. and Broz, P. (2014) “Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases”, Nature. Macmillan, 509(7500), pp. 366–370. doi: 10.1038/nature13157.   edoc
Alain Mazé, Timo Glatter and Dirk Bumann (2014) “The central metabolism regulator EIIAGlc switches Salmonella from growth arrest to acute virulence through activation of virulence factor secretion”, Cell reports. Elsevier, Vol. 7, H. 5 , S. 1426–1433. doi: 10.1016/j.celrep.2014.04.022.   edoc | Open Access
Burton, N. A., Schürmann, N., Casse, O., Steeb, A. K., Claudi, B., Zankl, J., Schmidt, A. and Bumann, D. (2014) “Disparate Impact of Oxidative Host Defenses Determines the Fate of Salmonella during Systemic Infection in Mice”, Cell Host & Microbe. Cell Press, 15(1), pp. 72–83. doi: 10.1016/j.chom.2013.12.006.   edoc
Kwaik, Y. A. and Bumann, D. (2013) “Microbial quest for food in vivo : ‘Nutritional virulence’ as an emerging paradigm”, Cellular Microbiology. Wiley, 15(6), pp. 882–890. doi: 10.1111/cmi.12138.   edoc
Steeb, B., Claudi, B., Burton, N. A., Tienz, P., Schmidt, A., Farhan, H., Mazé, A. and Bumann, D. (2013) “Parallel exploitation of diverse host nutrients enhances salmonella virulence”, PLoS Pathogens. Public Library of Science, Vol. 9, H. 4 , e1003301. doi: 10.1371/journal.ppat.1003301.   edoc | Open Access
Mary, C., Duek, P., Salleron, L., Tienz, P., Bumann, D., Bairoch, A. and Lane, L. (2012) “Functional Identification of APIP as Human mtnB, a Key Enzyme in the Methionine Salvage Pathway”, PLoS ONE. Public Library of Science, 7(12), p. e52877. doi: 10.1371/journal.pone.0052877.   edoc | Open Access
Barat, S., Willer, Y., Rizos, K., Claudi, B., Mazé, A., Schemmer, A. K., Kirchhoff, D., Schmidt, A., Burton, N. and Bumann, D. (2012) “Immunity to intracellular Salmonella depends on surface-associated antigens”, PLoS Pathogens. Public Library of Science, Vol. 8, H. 10 , e1002966.   edoc | Open Access
Barat, S., Steeb, B., Mazé, A. and Bumann, D. (2012) “Extensive in vivo resilience of persistent Salmonella”, PLoS ONE. Public Library of Science, Vol. 7, H. 7 , e42007.   edoc | Open Access
Schrimpf, S. P., von Mering, C., Bendixen, E., Heazlewood, J. L., Bumann, D., Omenn, G. and Hengartner, M. O. (2012) “The initiative on Model Organism Proteomes (iMOP) Session September 6, 2011, Geneva, Switzerland”, Proteomics. Wiley, 12(3), pp. 346–350. doi: 10.1002/pmic.201290015.   edoc
Willer, Y., Müller, B. and Bumann, D. (2012) “Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination”, PLoS ONE. Public Library of Science, Vol. 7, H. 5 , e35992. doi: 10.1371/journal.pone.0035992.   edoc | Open Access
Leschner, S., Deyneko, I. V., Lienenklaus, S., Wolf, K., Bloecker, H., Bumann, D., Loessner, H. and Weiss, S. (2012) “Identification of tumor-specific Salmonella Typhimurium promoters and their regulatory logic”, Nucleic Acids Research. Oxford University Press, 40(7), pp. 2984–2994. doi: 10.1093/nar/gkr1041.   edoc | Open Access
Crull, K., Bumann, D. and Weiss, S. (2011) “Influence of infection route and virulence factors on colonization of solid tumors by Salmonella enterica serovar Typhimurium”, FEMS Immunology and Medical Microbiology. Blackwell, 62(1), pp. 75–83. doi: 10.1111/j.1574-695X.2011.00790.x.   edoc | Open Access
Thiele, I., Hyduke, D. R., Steeb, B., Fankam, G., Allen, D. K., Bazzani, S., Charusanti, P., Chen, F. .-C., Fleming, R. M. T., Hsiung, C. A., De Keersmaecker, S. C. J., Liao, Y. .-C., Marchal, K., Mo, M. L., Ozdemir, E., Raghunathan, A., Reed, J. L., Shin, S. .- il, Sigurbjornsdottir, S., Steinmann, J., Sudarsan, S., Swainston, N., Thijs, I. M., Zengler, K., Palsson, B. O., Adkins, J. N. and Bumann, D. (2011) “A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2”, BMC Systems Biology. BioMed Central, 5(8), pp. 1–9. doi: 10.1186/1752-0509-5-8.   edoc | Open Access
Hänisch, J., Kolm, R., Wozniczka, M., Bumann, D., Rottner, K. and Stradal, T. E. B. (2011) “Activation of a RhoA/Myosin II-Dependent but Arp2/3 Complex-Independent Pathway Facilitates Salmonella Invasion”, Cell Host & Microbe. Cell Press, 9(4), pp. 273–285. doi: 10.1016/j.chom.2011.03.009.   edoc
Stelter, C., Kappeli, R., Konig, C., Krah, A., Hardt, W. .-D., Stecher, B. and Bumann, D. (2011) “Salmonella-Induced Mucosal Lectin RegIIIbeta Kills Competing Gut Microbiota”, PLoS ONE. Public Library of Science, 6(6), p. e20749. doi: 10.1371/journal.pone.0020749.   edoc | Open Access
Wild, P., Farhan, H., McEwan, D. G., Wagner, S., Rogov, V. V., Brady, N. R., Richter, B., Korac, J., Waidmann, O., Choudhary, C., Dötsch, V., Bumann, D. and Dikic, I. (2011) “Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth”, Science. American Association for the Advancement of Science, 333(6039), pp. 228–233. doi: 10.1126/science.1205405.   edoc | Open Access
Pawelczyk, S., Bumann, D. and Abraham, W. R. (2011) “Kinetics of carbon sharing in a bacterial consortium revealed by combining stable isotope probing with fluorescence-activated cell sorting”, Journal of Applied Microbiology. Blackwell, 110(4), pp. 1065–1073. doi: 10.1111/j.1365-2672.2011.04964.x.   edoc
Bumann, D. (2010) “Pathogen proteomes during infection : a basis for infection research and novel control strategies”, Journal of Proteomics. Elsevier, 73(11), pp. 2267–2276. doi: 10.1016/j.jprot.2010.08.004.   edoc
Bumann, D., Behre, C., Behre, K., Herz, S., Gewecke, B., Gessner, J. E., von Specht, B. U. and Baumann, U. (2009) “Systemic, nasal and oral live vaccines against Pseudomonas aeruginosa : a clinical trial of immunogenicity in lower airways of human volunteers”, Vaccine. Elsevier, 28(3), pp. 707–713. doi: 10.1016/j.vaccine.2009.10.080.   edoc
de Buhr, M. F., Hedrich, H. J., Westendorf, A. M., Obermeier, F., Hofmann, C., Zschemisch, N. H., Buer, J., Bumann, D., Goyert, S. M. and Bleich, A. (2009) “Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice”, Inflammatory Bowel Diseases. Wiley, 15(12), pp. 1824–1836. doi: 10.1002/ibd.21030.   edoc
Bumann, D. (2009) “System-level analysis of Salmonella metabolism during infection”, Current Opinion in Microbiology. Elsevier, 12(5), pp. 559–567. doi: 10.1016/j.mib.2009.08.004.   edoc
Hänisch, J., Ehinger, J., Ladwein, M., Rohde, M., Derivery, E., Bosse, T., Steffen, A., Bumann, D., Misselwitz, B., Hardt, W. D., Gautreau, A., Stradal, T. E. and Rottner, K. (2009) “Molecular dissection of Salmonella-induced membrane ruffling versus invasion”, Cellular Microbiology. Blackwell, 12(1), pp. 84–98. doi: 10.1111/j.1462-5822.2009.01380.x.   edoc
Aebischer, T., Bumann, D., Epple, H. J., Metzger, W., Schneider, T., Cherepnev, G., Walduck, A. K., Kunkel, D., Moos, V., Loddenkemper, C., Jiadze, I., Panasyuk, M., Stolte, M., Graham, D. Y., Zeitz, M. and Meyer, T. F. (2008) “Correlation of T cell response and bacterial clearance in human volunteers challenged with Helicobacter pylori revealed by randomised controlled vaccination with Ty21a-based Salmonella vaccines”, Gut. British Medical Association, 57(8), pp. 1065–1072. doi: 10.1136/gut.2007.145839.   edoc | Open Access
Bumann, D. and Buss, L. (2008) “Nutritional physiology and colony form in Podocoryna carnea (Cnidaria: Hydrozoa)”, Invertebrate Biology. Blackwell, 127(4), pp. 368–380. doi: 10.1111/j.1744-7410.2008.00135.x.   edoc
Bumann, D. (2008) “Has nature already identified all useful antibacterial targets?”, Current Opinion in Microbiology. Elsevier, 11(5), pp. 387–392. doi: 10.1016/j.mib.2008.08.002.   edoc
Bumann, D. and Valdivia, R. H. (2007) “Identification of host-induced pathogen genes by differential fluorescence induction reporter systems”, Nature Protocols. Nature Publishing Group, 2(4), pp. 770–777. doi: 10.1038/nprot.2007.78.   edoc
Kirchhoff, D., Frentsch, M., Leclerk, P., Bumann, D., Rausch, S., Hartmann, S., Thiel, A. and Scheffold, A. (2007) “Identification and isolation of murine antigen-reactive T cells according to CD154 expression”, European Journal of Immunology. Wiley, 37(9), pp. 2370–2377. doi: 10.1002/eji.200737322.   edoc
Thone, F., Schwanhausser, B., Becker, D., Ballmaier, M. and Bumann, D. (2007) “FACS-isolation of Salmonella-infected cells with defined bacterial load from mouse spleen”, Journal of Microbiological Methods. Elsevier, 71(3), pp. 220–224. doi: 10.1016/j.mimet.2007.08.016.   edoc
Halle, S., Bumann, D., Herbrand, H., Willer, Y., Dahne, S., Forster, R. and Pabst, O. (2007) “Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium”, Infection and Immunity. American Society for Microbiology, 75(4), pp. 1577–1585. doi: 10.1128/IAI.01392-06.   edoc
Becker, D., Selbach, M., Rollenhagen, C., Ballmaier, M., Meyer, T. F., Mann, M. and Bumann, D. (2006) “Robust Salmonella metabolism limits possibilities for new antimicrobials”, Nature. Macmillan, 440(7082), pp. 303–307. doi: 10.1038/nature04616.   edoc
Rollenhagen, C. and Bumann, D. (2006) “Salmonella enterica highly expressed genes are disease specific”, Infection and Immunity. American Society for Microbiology, 74(3), pp. 1649–1660. doi: 10.1128/IAI.74.3.1649-1660.2006.   edoc
Sabarth, N., Hurvitz, R., Schmidt, M., Zimny-Arndt, U., Jungblut, P. R., Meyer, T. F. and Bumann, D. (2005) “Identification of Helicobacter pylori surface proteins by selective proteinase K digestion and antibody phage display”, Journal of Microbiological Methods. Elsevier, 62(3), pp. 345–349. doi: 10.1016/j.mimet.2005.04.030.   edoc
Rollenhagen, C., Sorensen, M., Rizos, K., Hurvitz, R. and Bumann, D. (2004) “Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen”, Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 101(23), pp. 8739–8744. doi: 10.1073/pnas.0401283101.   edoc
Metzger, W. G., Mansouri, E., Kronawitter, M., Diescher, S., Soerensen, M., Hurwitz, R., Bumann, D., Aebischer, T., Von Specht, B. .-U. and Meyer, T. F. (2004) “Impact of vector-priming on the immunogenicity of a live recombinant Salmonella enterica serovar typhi Ty21a vaccine expressing urease A and B from Helicobacter pylori in human volunteers”, Vaccine. Elsevier, 22(17-18), pp. 2273–2277. doi: 10.1016/j.vaccine.2003.11.020.   edoc
Arnold, H., Bumann, D., Felies, M., Gewecke, B., Sorensen, M., Gessner, J. E., Freihorst, J., von Specht, B. U. and Baumann, U. (2004) “Enhanced immunogenicity in the murine airway mucosa with an attenuated Salmonella live vaccine expressing OprF-OprI from Pseudomonas aeruginosa”, Infection and Immunity. American Society for Microbiology, 72(11), pp. 6546–6553. doi: 10.1128/IAI.72.11.6546-6553.2004.   edoc
Bumann, D., Habibi, H., Kan, B., Schmid, M., Goosmann, C., Brinkmann, V., Meyer, T. F. and Jungblut, P. R. (2004) “Lack of stage-specific proteins in coccoid Helicobacter pylori cells”, Infection and Immunity. American Society for Microbiology, 72(11), pp. 6738–6742. doi: 10.1128/IAI.72.11.6738-6742.2004.   edoc
Bumann, D., Jungblut, P. R. and Meyer, T. F. (2004) “Helicobacter pylori vaccine development based on combined subproteome analysis”, Proteomics. Wiley, 4(10), pp. 2843–2848. doi: 10.1002/pmic.200400909.   edoc
Bumann, D., Jungblut, P. R. and Meyer, T. F. (2003) “Helicobacter vaccine development based on global approaches”, Genome Letters. American Scientific Publishers, 2(1-2), pp. 94–98. doi: 10.1166/gl.2003.000.   edoc
Bumann, D. (2003) “T cell receptor-transgenic mouse models for studying cellular immune responses to Salmonella in vivo”, FEMS Immunology and Medical Microbiology. Elsevier, 37(2-3), pp. 105–109. doi: 10.1016/S0928-8244(03)00064-6.   edoc | Open Access
Sorensen, M., Lippuner, C., Kaiser, T., Misslitz, A., Aebischer, T. and Bumann, D. (2003) “Rapidly maturing red fluorescent protein variants with strongly enhanced brightness in bacteria”, FEBS Letters. Elsevier, 552(2-3), pp. 110–114. doi: 10.1016/S0014-5793(03)00856-1.   edoc
Daugelat, S., Kowall, J., Mattow, J., Bumann, D., Winter, R., Hurwitz, R. and Kaufmann, S. H. E. (2003) “The RD1 proteins of Mycobacterium tuberculosis : expression in Mycobacterium smegmatis and biochemical characterization”, Microbes and Infection. Elsevier, 5(12), pp. 1082–1095. doi: 10.1016/S1286-4579(03)00205-3.   edoc
Rizos, K., Lattemann, C. T., Bumann, D., Meyer, T. F. and Aebischer, T. (2003) “Autodisplay : efficacious surface exposure of antigenic UreA fragments from Helicobacter pylori in Salmonella vaccine strains”, Infection and Immunity. American Society for Microbiology, 71(11), pp. 6320–6328. doi: 10.1128/IAI.71.11.6320-6328.2003.   edoc
Jungblut, P. R. and Bumann, D. (2002) “Immunoproteome of Helicobacter pylori”, Methods in Enzymology. Elsevier, 358, pp. 307–316. doi: 10.1016/S0076-6879(02)58097-6.   edoc
Sabarth, N., Lamer, S., Zimny-Arndt, U., Jungblut, P. R., Meyer, T. F. and Bumann, D. (2002) “Identification of surface proteins of Helicobacter pylori by selective biotinylation, affinity purification, and two-dimensional gel electrophoresis”, Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 277(31), pp. 27896–27902. doi: 10.1074/jbc.M204473200.   edoc | Open Access
Sabarth, N., Hurwitz, R., Meyer, T. F. and Bumann, D. (2002) “Multiparameter selection of Helicobacter pylori antigens identifies two novel antigens with high protective efficacy”, Infection and Immunity. American Society for Microbiology, 70(11), pp. 6499–6503. doi: 10.1128/IAI.70.11.6499-6503.2002.   edoc
Wendland, M. and Bumann, D. (2002) “Optimization of GFP levels for analyzing Salmonella gene expression during an infection”, FEBS Letters. Elsevier, 521(1-3), pp. 105–108. doi: 10.1016/S0014-5793(02)02834-X.   edoc
Bumann, D., Holland, P., Siejak, F., Koesling, J., Sabarth, N., Lamer, S., Zimny-Arndt, U., Jungblut, P. R. and Meyer, T. F. (2002) “A comparison of murine and human immunoproteomes of Helicobacter pylori validates the preclinical murine infection model for antigen screening”, Infection and Immunity. American Society for Microbiology, 70(11), pp. 6494–6498. doi: 10.1128/IAI.70.11.6494-6498.2002.   edoc
Bumann, D. (2002) “Examination of Salmonella gene expression in an infected mammalian host using the green fluorescent protein and two-colour flow cytometry”, Molecular Microbiology. Blackwell, 43(5), pp. 1269–1283. doi: 10.1046/j.1365-2958.2002.02821.x.   edoc
Bumann, D., Aksu, S., Wendland, M., Janek, K., Zimny-Arndt, U., Sabarth, N., Meyer, T. F. and Jungblut, P. R. (2002) “Proteome analysis of secreted proteins of the gastric pathogen Helicobacter pylori”, Infection and Immunity. American Society for Microbiology, 70(7), pp. 3396–3403. doi: 10.1128/IAI.70.7.3396-3403.2002.   edoc
Bumann, D., Metzger, W. G., Mansouri, E., Palme, O., Wendland, M., Hurwitz, R., Haas, G., Aebischer, T., von Specht, B. U. and Meyer, T. F. (2001) “Safety and immunogenicity of live recombinant Salmonella enterica serovar Typhi Ty21a expressing urease A and B from Helicobacter pylori in human volunteers”, Vaccine. Elsevier, 20(5-6), pp. 845–852. doi: 10.1016/S0264-410X(01)00391-7.   edoc
Lucas, B., Bumann, D., Walduck, A., Koesling, J., Develioglu, L., Meyer, T. F. and Aebischer, T. (2001) “Adoptive transfer of CD4+ T cells specific for subunit A of Helicobacter pylori urease reduces H. pylori stomach colonization in mice in the absence of interleukin-4 (IL-4)/IL-13 receptor signaling”, Infection and Immunity. American Society for Microbiology, 69(3), pp. 1714–1721. doi: 10.1128/IAI.69.3.1714-1721.2001.   edoc
Bumann, D. (2001) “Regulated antigen expression in live recombinant Salmonella enterica serovar Typhimurium strongly affects colonization capabilities and specific CD4(+)-T-cell responses”, Infection and Immunity. American Society for Microbiology, 69(12), pp. 7493–7500. doi: 10.1128/IAI.69.12.7493-7500.2001.   edoc
Bumann, D. (2001) “In vivo visualization of bacterial colonization, antigen expression, and specific T-cell induction following oral administration of live recombinant Salmonella enterica serovar Typhimurium”, Infection and Immunity. American Society for Microbiology, 69(7), pp. 4618–4626. doi: 10.1128/IAI.69.7.4618-4626.2001.   edoc
Jungblut, P. R., Bumann, D., Haas, G., Zimny-Arndt, U., Holland, P., Lamer, S., Siejak, F., Aebischer, A. and Meyer, T. F. (2000) “Comparative proteome analysis of Helicobacter pylori”, Molecular Microbiology. Blackwell, 36(3), pp. 710–725. doi: 10.1046/j.1365-2958.2000.01896.x.   edoc
Bumann, D., Hueck, C., Aebischer, T. and Meyer, T. F. (2000) “Recombinant live Salmonella spp. for human vaccination against heterologous pathogens”, FEMS Immunology and Medical Microbiology. Elsevier, 27(4), pp. 357–364. doi: 10.1111/j.1574-695X.2000.tb01450.x.   edoc | Open Access
Aebischer, T., Lucas, B., Koesling, J., Bumann, D. and Meyer, T. F. (2000) “How CD4(+) T cells may eliminate extracellular gastric Helicobacter?”, Journal of Biotechnology. Elsevier, 83(1-2), pp. 77–84. doi: 10.1016/S0168-1656(00)00301-1.   edoc
Gomez-Duarte, O. G., Bumann, D. and Meyer, T. F. (1999) “The attenuated Salmonella vaccine approach for the control of Helicobacter pylori-related diseases”, Vaccine. Elsevier, 17(13-14), pp. 1667–1673. doi: 10.1016/S0264-410X(98)00436-8.   edoc
Bumann, D. and Puls, G. (1997) “The ctenophore Mnemiopsis leidyi has a flow-through system for digestion with three consecutive phases of extracellular digestion”, Physiological Zoology. University of Chicago Press, 70(1), pp. 1–6. doi: 10.1086/639529.   edoc | Open Access
Bumann, D. and Oesterhelt, D. (1995) “Destruction of a single chlorophyll is correlated with the photoinhibition of photosystem II with a transiently inactive donor side”, Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences, 92(26), pp. 12195–12199.   edoc
Bumann, D. and Oesterhelt, D. (1994) “Purification and characterization of oxygen-evolving photosystem II core complexes from the green alga Chlamydomonas reinhardtii”, Biochemistry. American Chemical Society, 33(36), pp. 10906–10910. doi: 10.1021/bi00202a009.   edoc