Publications

Wee, C. L., Nikitchenko, M., Wang, W.-C., Luks-Morgan, S. J., Song, E., Gagnon, J. A., Randlett, O., Bianco, I. H., Lacoste, A. M. B., Glushenkova, E., Barrios, J. P., Schier, A. F., Kunes, S., Engert, F. und Douglass, A. D. (2019) «Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets», Nature neuroscience, 22(9), S. 1477-1492. doi: 10.1038/s41593-019-0452-x.   
Haesemeyer, M., Schier, A. F. und Engert, F. (2019) «Convergent Temperature Representations in Artificial and Biological Neural Networks», Neuron, 103(6), S. 1123-1134.e6. doi: 10.1016/j.neuron.2019.07.003.   
Goudarzi, M., Berg, K., Pieper, L. M. und Schier, A. F. (2019) «Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility», eLife, 8, S. 8:e40815. doi: 10.7554/eLife.40815.   
Ma 马漫修M., Ramirez, A. D., Wang 王彤T., Roberts, R. L., Harmon, K. E., Schoppik, D., Sharma, A., Kuang, C., Goei, S. L., Gagnon, J. A., Zimmerman, S., Tsai, S. Q., Reyon, D., Joung, J. K., Aksay, E. R. F., Schier, A. F. und Pan 潘於勤Y. A. (2019) «Zebrafish dscaml1 Deficiency Impairs Retinal Patterning and Oculomotor Function», The Journal of neuroscience : the official journal of the Society for Neuroscience, S. Epubaheadofrint. doi: 10.1523/JNEUROSCI.1783-19.2019.   
Randlett, O., Haesemeyer, M., Forkin, G., Shoenhard, H., Schier, A. F., Engert, F. und Granato, M. (2019) «Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish», Current biology : CB, 29(8), S. 1337-1345.e4. doi: 10.1016/j.cub.2019.02.039.   
Thyme, S. B., Pieper, L. M., Li, E. H., Pandey, S., Wang, Y., Morris, N. S., Sha, C., Choi, J. W., Herrera, K. J., Soucy, E. R., Zimmerman, S., Randlett, O., Greenwood, J., McCarroll, S. A. und Schier, A. F. (2019) «Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions», Cell, 177(2), S. 478-491.e20. doi: 10.1016/j.cell.2019.01.048.   
Raj, B., Gagnon, J. A. und Schier, A. F. (2018) «Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR-Cas9 barcodes by scGESTALT», Nature protocols, 13(11), S. 2685-2713. doi: 10.1038/s41596-018-0058-x.   edoc
Montague, T. G., Gagnon, J. A. und Schier, A. F. (2018) «Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse», Development (Cambridge, England), 145(24), S. 9. doi: 10.1242/dev.171090.   edoc
Haesemeyer, M., Robson, D. N., Li, J. M., Schier, A. F. und Engert, F. (2018) «A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish», Neuron, 98(4), S. 817-831.e6. doi: 10.1016/j.neuron.2018.04.013.   edoc
Almuedo-Castillo, M., Bläßle, A., Mörsdorf, D., Marcon, L., Soh, G. H., Rogers, K. W., Schier, A. F. und Müller, P. (2018) «Scale-invariant patterning by size-dependent inhibition of Nodal signalling», Nature cell biology, 20(9), S. 1032-1042. doi: 10.1038/s41556-018-0155-7.   edoc
Raj, B., Wagner, D. E., McKenna, A., Pandey, S., Klein, A. M., Shendure, J., Gagnon, J. A. und Schier, A. F. (2018) «Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain», Nature biotechnology, 36(5), S. 442-450. doi: 10.1038/nbt.4103.   edoc
Farrell, J. A., Wang, Y., Riesenfeld, S. J., Shekhar, K., Regev, A. und Schier, A. F. (2018) «Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis», Science (New York, N.Y.), 360(6392), S. 6. doi: 10.1126/science.aar3131.   edoc
Gagnon, J. A., Obbad, K. und Schier, A. F. (2018) «The primary role of zebrafish nanog is in extra-embryonic tissue», Development (Cambridge, England), 145(1), S. 9. doi: 10.1242/dev.147793.   edoc
Pandey, S., Shekhar, K., Regev, A. und Schier, A. F. (2018) «Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq», Current biology : CB, 28(7), S. 1052-1065.e7. doi: 10.1016/j.cub.2018.02.040.   edoc
Rogers, K. W., Lord, N. D., Gagnon, J. A., Pauli, A., Zimmerman, S., Aksel, D. C., Reyon, D., Tsai, S. Q., Joung, J. K. und Schier, A. F. (2017) «Nodal patterning without Lefty inhibitory feedback is functional but fragile», eLife, 6, S. 6:e28785. doi: 10.7554/eLife.28785.   edoc
Rabani, M., Pieper, L., Chew, G.-L. und Schier, A. F. (2017) «A Massively Parallel Reporter Assay of 3’ UTR Sequences Identifies In Vivo Rules for mRNA Degradation», Molecular Cell, 68(6), S. 1083-1094.e5. doi: 10.1016/j.molcel.2017.11.014.   edoc
Norris, M. L., Pauli, A., Gagnon, J. A., Lord, N. D., Rogers, K. W., Mosimann, C., Zon, L. I. und Schier, A. F. (2017) «Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling», eLife, 6, S. 6:e22626. doi: 10.7554/eLife.22626.   edoc
Montague, T. G. und Schier, A. F. (2017) «Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm», eLife, 6, S. 6:e28183. doi: 10.7554/eLife.28183.   edoc
Schoppik, D., Bianco, I. H., Prober, D. A., Douglass, A. D., Robson, D. N., Li, J. M. B., Greenwood, J. S. F., Soucy, E., Engert, F. und Schier, A. F. (2017) «Gaze-Stabilizing Central Vestibular Neurons Project Asymmetrically to Extraocular Motoneuron Pools», The Journal of Neuroscience, 37(47), S. 11353-11365. doi: 10.1523/JNEUROSCI.1711-17.2017.   edoc
Escamilla, C. O., Filonova, I., Walker, A. K., Xuan, Z. X., Holehonnur, R., Espinosa, F., Liu, S., Thyme, S. B., López-García, I. A., Mendoza, D. B., Usui, N., Ellegood, J., Eisch, A. J., Konopka, G., Lerch, J. P., Schier, A. F., Speed, H. E. und Powell, C. M. (2017) «Kctd13 deletion reduces synaptic transmission via increased RhoA», Nature, 551(7679), S. 227-231. doi: 10.1038/nature24470.   edoc
Hildebrand, D. G. C., Cicconet, M., Torres, R. M., Choi, W., Quan, T. M., Moon, J., Wetzel, A. W., Scott Champion, A., Graham, B. J., Randlett, O., Plummer, G. S., Portugues, R., Bianco, I. H., Saalfeld, S., Baden, A. D., Lillaney, K., Burns, R., Vogelstein, J. T., Schier, A. F., Lee, W.-C. A., Jeong, W.-K., Lichtman, J. W. und Engert, F. (2017) «Whole-brain serial-section electron microscopy in larval zebrafish», Nature, 545(7654), S. 345-349. doi: 10.1038/nature22356.   edoc
Freyer, L., Hsu, C.-W., Nowotschin, S., Pauli, A., Ishida, J., Kuba, K., Fukamizu, A., Schier, A. F., Hoodless, P. A., Dickinson, M. E. und Hadjantonakis, A.-K. (2017) «Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives», Cell reports. Cell Press, 20(9), S. 2116-2130. doi: 10.1016/j.celrep.2017.08.014.   edoc
Thyme, S. B., Akhmetova, L., Montague, T. G., Valen, E. und Schier, A. F. (2016) «Internal guide RNA interactions interfere with Cas9-mediated cleavage», Nature communications, 7, S. 11750. doi: 10.1038/ncomms11750.   edoc
Chew, G.-L., Pauli, A. und Schier, A. F. (2016) «Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish», Nature communications, 7, S. 11663. doi: 10.1038/ncomms11663.   edoc
McKenna, A., Findlay, G. M., Gagnon, J. A., Horwitz, M. S., Schier, A. F. und Shendure, J. (2016) «Whole-organism lineage tracing by combinatorial and cumulative genome editing», Science (New York, N.Y.), 353(6298), S. aaf7907. doi: 10.1126/science.aaf7907.   edoc
Thyme, S. B. und Schier, A. F. (2016) «Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development», Cell reports. CellPress, 15(4), S. 707-714. doi: 10.1016/j.celrep.2016.03.072.   edoc
Dunn, T. W., Mu, Y., Narayan, S., Randlett, O., Naumann, E. A., Yang, C.-T., Schier, A. F., Freeman, J., Engert, F. und Ahrens, M. B. (2016) «Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion», eLife, 5, S. e12741. doi: 10.7554/eLife.12741.   edoc
Li-Villarreal, N., Forbes, M. M., Loza, A. J., Chen, J., Ma, T., Helde, K., Moens, C. B., Shin, J., Sawada, A., Hindes, A. E., Dubrulle, J., Schier, A. F., Longmore, G. D., Marlow, F. L. und Solnica-Krezel, L. (2016) «Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis», Development. Company of Biologists, 143(10), S. 1832. doi: 10.1242/dev.138859.   edoc
Chiu, C. N., Rihel, J., Lee, D. A., Singh, C., Mosser, E. A., Chen, S., Sapin, V., Pham, U., Engle, J., Niles, B. J., Montz, C. J., Chakravarthy, S., Zimmerman, S., Salehi-Ashtiani, K., Vidal, M., Schier, A. F. und Prober, D. A. (2016) «A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States», Neuron, 89(4), S. 842-856. doi: 10.1016/j.neuron.2016.01.007.   edoc
Li-Villarreal, N., Forbes, M. M., Loza, A. J., Chen, J., Ma, T., Helde, K., Moens, C. B., Shin, J., Sawada, A., Hindes, A. E., Dubrulle, J., Schier, A. F., Longmore, G. D., Marlow, F. L. und Solnica-Krezel, L. (2015) «Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis», Development. Company of Biologists, 142(15), S. 2704-2718. doi: 10.1242/dev.119800.   edoc
Dubrulle, J., Jordan, B. M., Akhmetova, L., Farrell, J. A., Kim, S.-H., Solnica-Krezel, L. und Schier, A. F. (2015) «Response to Nodal morphogen gradient is determined by the kinetics of target gene induction», eLife. eLife Sciences Publications , 4, S. e05042. doi: 10.7554/eLife.05042.   edoc
Pauli, A., Valen, E. und Schier, A. F. (2015) «Identifying (non-)coding RNAs and small peptides: challenges and opportunities», BioEssays : news and reviews in molecular, cellular and developmental biology, 37(1), S. 103-112. doi: 10.1002/bies.201400103.   edoc
Haesemeyer, M. und Schier, A. F. (2015) «The study of psychiatric disease genes and drugs in zebrafish», Current Opinion in Neurobiology. Elsevier, 30, S. 122-130. doi: 10.1016/j.conb.2014.12.002.   edoc
Rogers, K. W., Blässle, A., Schier, A. F. und Müller, P. (2015) «Measuring protein stability in living zebrafish embryos using fluorescence decay after photoconversion (FDAP)», Journal of visualized experiments. JoVE, (95), S. e52266. doi: 10.3791/52266.   edoc
Merkle, F. T., Maroof, A., Wataya, T., Sasai, Y., Studer, L., Eggan, K. und Schier, A. F. (2015) «Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells», Development (Cambridge, England), 142(4), S. 633-643. doi: 10.1242/dev.117978.   edoc
Pauli, A., Montague, T. G., Lennox, K. A., Behlke, M. A. und Schier, A. F. (2015) «Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish», PloS one, 10(10), S. e0139504. doi: 10.1371/journal.pone.0139504.   edoc
Mundell, N. A., Beier, K. T., Pan, Y. A., Lapan, S. W., Göz Aytürk, D., Berezovskii, V. K., Wark, A. R., Drokhlyansky, E., Bielecki, J., Born, R. T., Schier, A. F. und Cepko, C. L. (2015) «Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms», Journal of Comparative Neurology. Wiley, 523(11), S. 1639-1663. doi: 10.1002/cne.23761.   edoc
Liu, J., Merkle, F. T., Gandhi, A. V., Gagnon, J. A., Woods, I. G., Chiu, C. N., Shimogori, T., Schier, A. F. und Prober, D. A. (2015) «Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9», Development. Company of Biologists, 142(6), S. 1113-1124. doi: 10.1242/dev.117424.   edoc
Satija, R., Farrell, J. A., Gennert, D., Schier, A. F. und Regev, A. (2015) «Spatial reconstruction of single-cell gene expression data», Nature biotechnology, 33(5), S. 495-502. doi: 10.1038/nbt.3192.   edoc
Merkle, F. T., Neuhausser, W. M., Santos, D., Valen, E., Gagnon, J. A., Maas, K., Sandoe, J., Schier, A. F. und Eggan, K. (2015) «Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus», Cell Reports . Elsevier, 11(6), S. 875-883. doi: 10.1016/j.celrep.2015.04.007.   edoc