Publications

Schnoz, C., Moser, S., Kratschmar, D. V., Odermatt, A., Loffing-Cueni, D. and Loffing, J. (2021) “Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC”, Pflügers Archiv : European journal of physiology. Springer, 473(1), pp. 79–93. doi: 10.1007/s00424-020-02491-1.   edoc | Open Access
Beck, K. R. and Odermatt, A. (2021) “Antifungal therapy with azoles and the syndrome of acquired mineralocorticoid excess”, Molecular and Cellular Endocrinology. Elsevier, 524, p. 111168. doi: 10.1016/j.mce.2021.111168.   edoc | Open Access
Inderbinen, S. G., Zogg, M., Kley, M., Smieško, M. and Odermatt, A. (2021) “Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by itraconazole and posaconazole”, Toxicology and applied pharmacology. Academic Press, 412, p. 115387. doi: 10.1016/j.taap.2020.115387.   edoc | Open Access
Davis, M. R., Nguyen, M.-V. H., Gintjee, T. J., Odermatt, A., Young, B. Y. and Thompson, G. R. (2020) “Management of posaconazole-induced pseudohyperaldosteronism”, Journal of Antimicrobial Chemotherapy. Oxford University Press, 75(12), pp. 3688–3693. doi: 10.1093/jac/dkaa366.   edoc
Patt, M., Gysi, J., Faresse, N., Cidlowski, J. A. and Odermatt, A. (2020) “Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211”, Molecular and cellular endocrinology. Elsevier, 518, p. 110873. doi: 10.1016/j.mce.2020.110873.   edoc | Open Access
Thompson, G. R., Surampudi, P. N. and Odermatt, A. (2020) “Gynecomastia and hypertension in a patient treated with posaconazole”, Clinical case reports. Wiley, 8(12), pp. 3157–3160. doi: 10.1002/ccr3.3376.   edoc | Open Access
Mayr, F., Möller, G., Garscha, U., Fischer, J., Rodríguez Castaño, P., Inderbinen, S. G., Temml, V., Waltenberger, B., Schwaiger, S., Hartmann, R. W., Gege, C., Martens, S., Odermatt, A., Pandey, A. V., Werz, O., Adamski, J., Stuppner, H. and Schuster, D. (2020) “Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction”, International Journal of Molecular Sciences. Molecular Diversity Preservation International, 21(19), p. 7102. doi: 10.3390/ijms21197102.   edoc | Open Access
Tsachaki, M., Strauss, P., Dunkel, A., Navrátilová, H., Mladenovic, N. and Odermatt, A. (2020) “Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration”, Cellular and Molecular Life Sciences. Springer, 77(6), pp. 1153–1175. doi: 10.1007/s00018-019-03227-w.   edoc | Open Access
Nguyen, M.-V. H., Davis, M. R., Wittenberg, R., McHardy, I., Baddley, J. W., Young, B. Y., Odermatt, A. and Thompson, G. R. (2020) “Posaconazole Serum Drug Levels Associated With Pseudohyperaldosteronism”, Clinical Infectious Diseases. Oxford University Press, 70(12), pp. 2593–2598. doi: 10.1093/cid/ciz741.   edoc
Gómez, C., Stücheli, S., Kratschmar, D. V., Bouitbir, J. and Odermatt, A. (2020) “Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples”, Metabolites. MDPI, 10(7), p. 282. doi: 10.3390/metabo10070282.   edoc | Open Access
Schulze, F., Wehner, J., Kratschmar, D. V., Makshana, V., Meier, D. T., Häuselmann, S. P., Dalmas, E., Thienel, C., Dror, E., Wiedemann, S. J., Traub, S., Nordmann, T. M., Rachid, L., De Baat, A., Rohm, T. V., Zhao, C., Odermatt, A., Böni-Schnetzler, M. and Donath, M. Y. (2020) “Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes”, Scientific Reports. Nature Publishing Group, 10(1), p. 3035. doi: 10.1038/s41598-020-59701-0.   edoc | Open Access
Beck, K. R., Thompson, G. R. and Odermatt, A. (2020) “Drug-induced endocrine blood pressure elevation”, Pharmacological Research. Elsevier, 154, p. 104311. doi: 10.1016/j.phrs.2019.104311.   edoc | Open Access
Lizák, B., Birk, J., Zana, M., Kosztyi, G., Kratschmar, D. V., Odermatt, A., Zimmermann, R., Geiszt, M., Appenzeller-Herzog, C. and Bánhegyi, G. (2020) “Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione”, BMC Biology. BioMed Central, 18(1), p. 19. doi: 10.1186/s12915-020-0749-y.   edoc | Open Access
Randi, E. B., Vervaet, B., Tsachaki, M., Porto, E., Vermeylen, S., Lindenmeyer, M. T., Thuy, L. T. T., Cohen, C. D., Devuyst, O., Kistler, A. D., Szabo, C., Kawada, N., Hankeln, T., Odermatt, A., Dewilde, S., Wenger, R. H. and Hoogewijs, D. (2020) “The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease”, Antioxidants & redox signaling, 32(16), pp. 1155–1171. doi: 10.1089/ars.2019.7868.   
Beck, K. R., Telisman, L., van Koppen, C. J., Thompson, G. R. and Odermatt, A. (2020) “Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals”, The Journal of steroid biochemistry and molecular biology, 199, p. 105605. doi: 10.1016/j.jsbmb.2020.105605.   
Inderbinen, S. G., Engeli, R. T., Rohrer, S. R., Di Renzo, E., Aengenheister, L., Buerki-Thurnherr, T. and Odermatt, A. (2020) “Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α”, Toxicology letters, 322, pp. 39–49. doi: 10.1016/j.toxlet.2020.01.001.   
Patt, M., Beck, K. R., Di Marco, T., Jäger, M.-C., González-Ruiz, V., Boccard, J., Rudaz, S., Hartmann, R. W., Salah, M., van Koppen, C. J., Grill, M. and Odermatt, A. (2020) “Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesis”, Biochemical pharmacology, 172, p. 113781. doi: 10.1016/j.bcp.2019.113781.   
Sandström, J., Kratschmar, D. V., Broyer, A., Poirot, O., Marbet, P., Chantong, B., Zufferey, F., Dos Santos, T., Boccard, J., Chrast, R., Odermatt, A. and Monnet-Tschudi, F. (2019) “In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice ”, Archives of toxicology, 93, pp. 1649–1664. doi: 10.1007/s00204-019-02455-0.   edoc
Boccard, J., Tonoli, D., Strajhar, P., Jeanneret, F., Odermatt, A. and Rudaz, S. (2019) “Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening”, Talanta. Elsevier, 195, pp. 77–86. doi: 10.1016/j.talanta.2018.11.019.   edoc
Tsachaki, M. and Odermatt, A. (2019) “Subcellular localization and membrane topology of 17β-hydroxysteroid dehydrogenases”, Molecular and cellular endocrinology. North Holland Publishing, 489, pp. 98–106. doi: 10.1016/j.mce.2018.07.003.   edoc
Beck, K. R., Kanagaratnam, S., Kratschmar, D. V., Birk, J., Yamaguchi, H., Sailer, A. W., Seuwen, K. and Odermatt, A. (2019) “Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2”, The Journal of steroid biochemistry and molecular biology. Elsevier, 190, pp. 19–28. doi: 10.1016/j.jsbmb.2019.03.011.   edoc
Crane, E. A., Heydenreuter, W., Beck, K. R., Strajhar, P., Vomacka, J., Smiesko, M., Mons, E., Barth, L., Neuburger, M., Vedani, A., Odermatt, A., Sieber, S. A. and Gademann, K. (2019) “Profiling withanolide A for therapeutic targets in neurodegenerative diseases”, Bioorganic & medicinal chemistry. Elsevier, 27(12), pp. 2508–2520. doi: 10.1016/j.bmc.2019.03.022.   edoc
Akram, M., Patt, M., Kaserer, T., Temml, V., Waratchareeyakul, W., Kratschmar, D. V., Haupenthal, J., Hartmann, R. W., Odermatt, A. and Schuster, D. (2019) “Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase”, Journal of Steroid Biochemistry and Molecular Biology. Elsevier, 192, p. 105358. doi: 10.1016/j.jsbmb.2019.04.007.   edoc
Egli, J., Schmucki, R., Loos, B., Reichl, S., Grabole, N., Roller, A., Ebeling, M., Odermatt, A. and Iglesias, A. (2019) “The genomic organization and expression pattern of the low-affinity Fc gamma receptors (FcγR) in the Göttingen minipig”, Immunogenetics. Springer, 71(2), pp. 123–136. doi: 10.1007/s00251-018-01099-1.   edoc
Trinh, B., Hepprich, M., Betz, M. J., Burkard, T., Cavelti-Weder, C., Seelig, E., Meienberg, F., Kratschmar, D. V., Beuschlein, F., Reincke, M., Odermatt, A., Hall, M. N., Donath, M. Y. and Swierczynska, M. M. (2019) “Treatment of Primary Aldosteronism with mTORC1 Inhibitors”, Journal of Clinical Endocrinology and Metabolism. Oxford University Press, 104(10), pp. 4703–4714. doi: 10.1210/jc.2019-00563.   edoc
Thompson, G. R., Beck, K. R., Patt, M., Kratschmar, D. V. and Odermatt, A. (2019) “Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2”, Journal of the Endocrine Society. Endocrine Society, 3(7), pp. 1361–1366. doi: 10.1210/js.2019-00189.   edoc | Open Access
Canonica, J., Frateschi, S., Boscardin, E., Ebering, A., Sergi, C., Jäger, Y., Peyrollaz, T., Mérillat, A.-M., Maillard, M., Klusonova, P., Odermatt, A., Koesters, R., Debonneville, A., Staub, O., Verouti, S. N. and Hummler, E. (2019) “Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl- Cotransporter NCC and Transiently Affects Sodium Handling”, Frontiers in physiology. Frontiers Media, 10, p. 989. doi: 10.3389/fphys.2019.00989.   edoc | Open Access
Keppner, A., Maric, D., Sergi, C., Ansermet, C., De Bellis, D., Kratschmar, D. V., Canonica, J., Klusonova, P., Fenton, R. A., Odermatt, A., Crambert, G., Hoogewijs, D. and Hummler, E. (2019) “Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion”, Scientific Reports. Nature Research, 9(1), p. 19540. doi: 10.1038/s41598-019-55995-x.   edoc | Open Access
Egli, J., Schlothauer, T., Spick, C., Seeber, S., Singer, T., Odermatt, A. and Iglesias, A. (2019) “The Binding of Human IgG to Minipig FcγRs - Implications for Preclinical Assessment of Therapeutic Antibodies”, Pharmaceutical research. Springer, 36(3), p. 47. doi: 10.1007/s11095-019-2574-y.   edoc | Open Access
Beck, K. R., Inderbinen, S. G., Kanagaratnam, S., Kratschmar, D. V., Jetten, A. M., Yamaguchi, H. and Odermatt, A. (2019) “11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ”, Journal of Lipid Research. American Society for Biochemistry and Molecular Biology, 60, pp. 1535–1546. doi: 10.1194/jlr.M092908.   edoc | Open Access
Strajhar, P., Vizeli, P., Patt, M., Dolder, P. C., Kratschmar, D. V., Liechti, M. E. and Odermatt, A. (2019) “Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study”, Journal of Steroid Biochemistry and Molecular Biology. Elsevier, 186, pp. 212–225. doi: 10.1016/j.jsbmb.2018.10.016.   edoc | Open Access
Boudon, S., Heidl, M., Vuorinen, A., Wandeler, E., Campiche, R., Odermatt, A. and Jackson, E. (2018) “Design, synthesis, and biological evaluation of novel selective peptide inhibitors of 11β-hydroxysteroid dehydrogenase 1”, Bioorganic & medicinal chemistry, 26(18), pp. 5128–5139. doi: 10.1016/j.bmc.2018.09.009.   edoc
Emmerich, J., van Koppen, C. J., Burkhart, J. L., Engeli, R. T., Hu, Q., Odermatt, A. and Hartmann, R. W. (2018) “Accelerated skin wound healing by selective 11β²-Hydroxylase (CYP11B1) inhibitors”, European journal of medicinal chemistry, 143, pp. 591–597. doi: 10.1016/j.ejmech.2017.11.018.   edoc
Dolder, P. C., Strajhar, P., Vizeli, P., Odermatt, A. and Liechti, M. E. (2018) “Acute effects of lisdexamfetamine and D-amphetamine on social cognition and cognitive performance in a placebo-controlled study in healthy subjects”, Psychopharmacology. Springer, 235(5), pp. 1389–1402. doi: 10.1007/s00213-018-4849-0.   edoc
Tsachaki, M., Mladenovic, N., Štambergová, H., Birk, J. and Odermatt, A. (2018) “Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balance”, FASEB journal. Federation of American Society of Experimental Biology, 32(5), pp. 2690–2705. doi: 10.1096/fj.201700870RR.   edoc | Open Access
Lister, A., Bourgeois, S., Imenez Silva, P. H., Rubio-Aliaga, I., Marbet, P., Walsh, J., Shelton, L. M., Keller, B., Verrey, F., Devuyst, O., Giesbertz, P., Daniel, H., Goldring, C. E., Copple, I. M., Wagner, C. A. and Odermatt, A. (2018) “NRF2 regulates the glutamine transporter Slc38a3 (SNAT3) in kidney in response to metabolic acidosis”, Scientific reports. Nature Research, 8(1), p. 5629. doi: 10.1038/s41598-018-24000-2.   edoc | Open Access
Liao, W.-H., Suendermann, C., Steuer, A. E., Pacheco Lopez, G., Odermatt, A., Faresse, N., Henneberg, M. and Langhans, W. (2018) “Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity”, JCI insight. American Society for Clinical Investigation, 3(14), p. e99015. doi: 10.1172/jci.insight.99015.   edoc | Open Access
Marbet, P., Klusonova, P., Birk, J., Kratschmar, D. V. and Odermatt, A. (2018) “Absence of hexose-6-phosphate dehydrogenase results in reduced overall glucose consumption but does not prevent 11β-hydroxysteroid dehydrogenase-1-dependent glucocorticoid activation”, The FEBS journal. Wiley, 285(21), pp. 3993–4004. doi: 10.1111/febs.14642.   edoc | Open Access
Engeli, R. T., Fürstenberger, C., Kratschmar, D. V. and Odermatt, A. (2018) “Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis”, Heliyon. Elsevier, 4(2), p. e00527. doi: 10.1016/j.heliyon.2018.e00527.   edoc | Open Access
Randazzo, G. M., Tonoli, D., Strajhar, P., Xenarios, I., Odermatt, A., Boccard, J. and Rudaz, S. (2017) “Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study”, Journal of Chromatography B. Elsevier, 1071, pp. 11–18. doi: 10.1016/j.jchromb.2017.04.032.   edoc
Jiménez-Canino, R., Lorenzo-Díaz, F., Odermatt, A., Bailey, M. A., Livingstone, D. E. W., Jaisser, F., Farman, N. and Alvarez de la Rosa, D. (2017) “11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation”, Endocrinology. Oxford University Press, 158(11), pp. 4047–4063. doi: 10.1210/en.2017-00440.   edoc
Engeli, R. T., Tsachaki, M., Hassan, H. A., Sager, C. P., Essawi, M. L., Gad, Y. Z., Kamel, A. K., Mazen, I. and Odermatt, A. (2017) “Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients”, The journal of sexual medicine, 14(9), pp. 1165–1174. doi: 10.1016/j.jsxm.2017.07.006.   edoc
Knöpfel, T., Pastor-Arroyo, E. M., Schnitzbauer, U., Kratschmar, D. V., Odermatt, A., Pellegrini, G., Hernando, N. and Wagner, C. A. (2017) “The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction”, Scientific reports, 7(1), p. 11018. doi: 10.1038/s41598-017-10390-2.   edoc
Dolder, P. C., Strajhar, P., Vizeli, P., Hammann, F., Odermatt, A. and Liechti, M. E. (2017) “Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects”, Frontiers in pharmacology, 8, p. 617. doi: 10.3389/fphar.2017.00617.   edoc
Engeli, R. T., Rohrer, S. R., Vuorinen, A., Herdlinger, S., Kaserer, T., Leugger, S., Schuster, D. and Odermatt, A. (2017) “Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases”, International Journal of Molecular Sciences, 18(9), pp. 1–13. doi: 10.3390/ijms18092007.   edoc | Open Access
Aghagolzadeh, P., Radpour, R., Bachtler, M., van Goor, H., Smith, E. R., Lister, A., Odermatt, A., Feelisch, M. and Pasch, A. (2017) “Hydrogen sulfide attenuates calcification of vascular smooth muscle cells via KEAP1/NRF2/NQO1 activation”, Atherosclerosis, 265, pp. 78–86. doi: 10.1016/j.atherosclerosis.2017.08.012.   edoc
Morgan, R. A., Beck, K. R., Nixon, M., Homer, N. Z. M., Crawford, A. A., Melchers, D., Houtman, R., Meijer, O. C., Stomby, A., Anderson, A. J., Upreti, R., Stimson, R. H., Olsson, T., Michoel, T., Cohain, A., Ruusalepp, A., Schadt, E. E., Björkegren, J. L. M., Andrew, R., Kenyon, C. J., Hadoke, P. W. F., Odermatt, A., Keen, J. A. and Walker, B. R. (2017) “Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity”, Scientific Reports, 7(1), p. 10633. doi: 10.1038/s41598-017-10410-1.   edoc | Open Access
Alesutan, I., Voelkl, J., Feger, M., Kratschmar, D. V., Castor, T., Mia, S., Sacherer, M., Viereck, R., Borst, O., Leibrock, C., Gawaz, M., Kuro-O, M., Pilz, S., Tomaschitz, A., Odermatt, A., Pieske, B., Wagner, C. A. and Lang, F. (2017) “Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells”, Scientific Reports, 7(1), p. 2059. doi: 10.1038/s41598-017-01882-2.   edoc | Open Access
Legeza, B., Marcolongo, P., Gamberucci, A., Varga, V., Bánhegyi, G., Benedetti, A. and Odermatt, A. (2017) “Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome”, Nutrients, 9(5), p. E426. doi: 10.3390/nu9050426.   edoc | Open Access
Vuorinen, A., Engeli, R. T., Leugger, S., Bachmann, F., Akram, M., Atanasov, A. G., Waltenberger, B., Temml, V., Stuppner, H., Krenn, L., Ateba, S. B., Njamen, D., Davis, R. A., Odermatt, A. and Schuster, D. (2017) “Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2”, Journal of Natural Products, 80(4), pp. 965–974. doi: 10.1021/acs.jnatprod.6b00950.   edoc | Open Access
Vuorinen, A., Engeli, R. T., Leugger, S., Kreutz, C. R., Schuster, D., Odermatt, A. and Matuszczak, B. (2017) “Phenylbenzenesulfonates and -sulfonamides as 17β-hydroxysteroid dehydrogenase type 2 inhibitors: Synthesis and SAR-analysis”, Bioorganic & Medicinal Chemistry Letters, 27(13), pp. 2982–2985. doi: 10.1016/j.bmcl.2017.05.005.   edoc
Beck, K. R., Kaserer, T., Schuster, D. and Odermatt, A. (2017) “Virtual screening applications in short-chain dehydrogenase/reductase research”, Journal of Steroid Biochemistry and Molecular Biology. Elsevier, 171, pp. 157–177. doi: 10.1016/j.jsbmb.2017.03.008.   edoc
Araya, S., Kratschmar, D. V., Tsachaki, M., Stücheli, S., Beck, K. R. and Odermatt, A. (2017) “DHRS7 (SDR34C1) - A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone?”, Journal of Steroid Biochemistry and Molecular Biology. Elsevier, 27, pp. 288–295. doi: 10.1016/j.jsbmb.2017.04.013.   edoc
Ben Rhouma, B., Kallabi, F., Mahfoudh, N., Ben Mahmoud, A., Engeli, R. T., Kamoun, H., Keskes, L., Odermatt, A. and Belguith, N. (2017) “Novel cases of Tunisian patients with mutations in the gene encoding 17β-hydroxysteroid dehydrogenase type 3 and a founder effect”, Journal of Steroid Biochemistry and Molecular Biology. Elsevier, 165(A), pp. 86–94. doi: 10.1016/j.jsbmb.2016.03.007.   edoc
Beck, K. R., Bächler, M., Vuorinen, A., Wagner, S., Akram, M., Griesser, U., Temml, V., Klusonova, P., Yamaguchi, H., Schuster, D. and Odermatt, A. (2017) “Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole”, Biochemical pharmacology. Elsevier, 130, pp. 93–103. doi: 10.1016/j.bcp.2017.01.010.   edoc
Bonifacio, A., Sanvee, G. M., Brecht, K., Kratschmar, D. V., Odermatt, A., Bouitbir, J. and Krähenbühl, S. (2017) “IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes”, Archives of Toxicology. Springer, 91(5), pp. 2223–2234. doi: 10.1007/s00204-016-1871-z.   edoc
Strajhar, P., Tonoli, D., Jeanneret, F., Imhof, R. M., Malagnino, V., Patt, M., Kratschmar, D. V., Boccard, J., Rudaz, S. and Odermatt, A. (2017) “Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids”, Toxicology. Elsevier, 381, pp. 51–63. doi: 10.1016/j.tox.2017.02.010.   edoc
Boudon, S. M., Vuorinen, A., Geotti-Bianchini, P., Wandeler, E., Kratschmar, D. V., Heidl, M., Campiche, R., Jackson, E. and Odermatt, A. (2017) “Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UV”, PLoS ONE. Public Library of Science, 12(2), p. e0171079. doi: 10.1371/journal.pone.0171079.   edoc | Open Access
Tsachaki, M., Meyer, A., Weger, B., Kratschmar, D. V., Tokarz, J., Adamski, J., Belting, H.-G., Affolter, M., Dickmeis, T. and Odermatt, A. (2017) “Absence of 11-keto reduction of cortisone and 11-ketotestosterone in the model organism zebrafish”, Journal of Endocrinology. BioScientifica, 232(2), pp. 323–335. doi: 10.1530/JOE-16-0495.   edoc
Canonica, J., Sergi, C., Maillard, M., Klusonova, P., Odermatt, A., Koesters, R., Loffing-Cueni, D., Loffing, J., Rossier, B., Frateschi, S. and Hummler, E. (2016) “Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype”, Pflügers Archiv : European journal of physiology. Springer, 468(5), pp. 895–908. doi: 10.1007/s00424-015-1785-2.   edoc
Mani, O., Nashev, L. G., Livelo, C., Baker, M. E. and Odermatt, A. (2016) “Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone”, The Journal of steroid biochemistry and molecular biology. Elsevier, 159, pp. 31–40. doi: 10.1016/j.jsbmb.2016.02.017.   edoc
Odermatt, A., Strajhar, P. and Engeli, R. T. (2016) “Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools”, The Journal of steroid biochemistry and molecular biology. Elsevier, 158, pp. 9–21. doi: 10.1016/j.jsbmb.2016.01.009.   edoc
Strajhar, P., Schmid, Y., Liakoni, E., Dolder, P. C., Rentsch, K. M., Kratschmar, D. V., Odermatt, A. and Liechti, M. E. (2016) “Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects”, Journal of Neuroendocrinology. Wiley, 28(3), p. 12374. doi: 10.1111/jne.12374.   edoc | Open Access
Rizner, T. L., Sasano, H., Choi, M. H., Odermatt, A. and Adamski, J. (2016) “Recommendations for description and validation for antibodies for research use”, The journal of steroid biochemistry and molecular biology. Pergamon, 156, pp. 40–42. doi: 10.1016/j.jsbmb.2015.11.021.   edoc
Beck, K. R., Sommer, T. J., Schuster, D. and Odermatt, A. (2016) “Evaluation of tetrabromobisphenol A effects on human glucocorticoid and androgen receptors: A comparison of results from human- with yeast-based in vitro assays”, Toxicology. Elsevier, 370, pp. 70–77. doi: 10.1016/j.tox.2016.09.014.   edoc
Engeli, R. T., Rhouma, B. B., Sager, C. P., Tsachaki, M., Birk, J., Fakhfakh, F., Keskes, L., Belguith, N. and Odermatt, A. (2016) “Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development”, The Journal of steroid biochemistry and molecular biology. Elsevier, 155, pp. 147–154. doi: 10.1016/j.jsbmb.2015.10.023.   edoc
Hammond, T. G., Moes, S., Youhanna, S., Jennings, P., Devuyst, O., Odermatt, A. and Jenö, P. (2016) “Development and characterization of a pseudo multiple reaction monitoring method for the quantification of human uromodulin in urine”, Bioanalysis. Future Science, 8(12), pp. 1279–1296. doi: 10.4155/bio-2016-0055.   edoc | Open Access
Kaserer, T., Beck, K., Akram, M., Odermatt, A. and Schuster, D. (2015) “Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases”, Molecules. MDPI, 20(12), pp. 22799–22832. doi: 10.3390/molecules201219880.   edoc
Shelton, L. M., Lister, A., Walsh, J., Jenkins, R. E., Wong, M. H. L., Rowe, C., Ricci, E., Ressel, L., Fang, Y., Demougin, P., Vukojevic, V., O’Neill, P. M., Goldring, C. E., Kitteringham, N. R., Park, B. K., Odermatt, A. and Copple, I. M. (2015) “Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney”, Kidney international. Springer, 88(6), pp. 1261–1273. doi: 10.1038/ki.2015.286.   edoc
Seibert, J. K., Quagliata, L., Quintavalle, C., Hammond, T. G., Terracciano, L. and Odermatt, A. (2015) “A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer”, Cancer medicine. Wiley, 4(11), pp. 1717–1729. doi: 10.1002/cam4.517.   edoc
Di Chiara, M., Glaudemans, B., Loffing-Cueni, D., Odermatt, A., Al-Hasani, H., Devuyst, O., Faresse, N. and Loffing, J. (2015) “Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney”, American journal of physiology. Gastrointestinal and liver physiology. American Physiological Society, 309(9), pp. F779-F790. doi: 10.1152/ajprenal.00139.2015.   edoc
Odermatt, A. and Klusonova, P. (2015) “11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story”, The journal of steroid biochemistry and molecular biology. Pergamon, 151, pp. 85–92. doi: 10.1016/j.jsbmb.2014.08.011.   edoc
Tsachaki, M., Birk, J., Egert, A. and Odermatt, A. (2015) “Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions”, Biochimica et biophysica acta. Molecular cell research. Elsevier, 1853(7), pp. 1672–1682. doi: 10.1016/j.bbamcr.2015.04.002.   edoc
Tonoli, D., Fürstenberger, C., Boccard, J., Hochstrasser, D., Jeanneret, F., Odermatt, A. and Rudaz, S. (2015) “Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells”, Chemical research in toxicology. American Chemical Society (ACS) , 28(5), pp. 955–966. doi: 10.1021/tx5005369.   edoc
Vuorinen, A., Seibert, J., Papageorgiou, V. P., Rollinger, J. M., Odermatt, A., Schuster, D. and Assimopoulou, A. N. (2015) “Pistacia lentiscus Oleoresin: Virtual Screening and Identification of Masticadienonic and Isomasticadienonic Acids as Inhibitors of 11β-Hydroxysteroid Dehydrogenase 1”, Planta medica. Thieme, 81(6), pp. 525–532. doi: 10.1055/s-0035-1545720.   edoc
Vuorinen, A., Odermatt, A. and Schuster, D. (2015) “Reprint of ‘In silico methods in the discovery of endocrine disrupting chemicals’”, The Journal of steroid biochemistry and molecular biology. Elsevier, 153(September 2015), pp. 93–101. doi: 10.1016/j.jsbmb.2015.08.015.   edoc
Vuorinen, A., Nashev, L. G., Odermatt, A., Rollinger, J. M. and Schuster, D. (2014) “Pharmacophore model refinement for 11β-hydroxysteroid dehydrogenase inhibitors: Search for modulators of intracellular glucocorticoid concentrations”, Molecular Informatics. Wiley, 33, pp. 15–25. doi: 10.1002/minf.201300063.   edoc
Boudon, S. M., Morandi, G., Prideaux, B., Staab, D., Junker, U., Odermatt, A., Stoeckli, M. and Bauer, D. (2014) “Evaluation of sparfloxacin distribution by mass spectrometry imaging in a phototoxicity model”, Journal of the American Society for Mass Spectrometry. Springer, 25(10), pp. 1803–1809. doi: 10.1007/s13361-014-0947-3.   edoc
Blüthgen, N., Meili, N., Chew, G., Odermatt, A. and Fent, K. (2014) “Accumulation and effects of the UV-filter octocrylene in adult and embryonic zebrafish (Danio rerio)”, Science of the Total Environment. Elsevier, 476-477, pp. 207–217. doi: 10.1016/j.scitotenv.2014.01.015.   edoc
Boudon, S. M., Plappert-Helbig, U., Odermatt, A. and Bauer, D. (2014) “Characterization of vemurafenib phototoxicity in a mouse model”, Review of Economic Dynamics. Elsevier, 137(1), pp. 259–267. doi: 10.1093/toxsci/kft237.   edoc
Copple, I. M., Shelton, L. M., Walsh, J., Kratschmar, D. V., Lister, A., Odermatt, A., Goldring, C. E., Dinkova-Kostova, A. T., Honda, T. and Park, B. K. (2014) “Chemical tuning enhances both potency toward nrf2 and in vitro therapeutic index of triterpenoids”, Review of Economic Dynamics. Elsevier, 140(2), pp. 462–469. doi: 10.1093/toxsci/kfu080.   edoc
Gai, Z., Chu, L., Hiller, C., Arsenijevic, D., Penno, C. A., Montani, J.-P., Odermatt, A. and Kullak-Ublick, G. A. (2014) “Effect of chronic renal failure on the hepatic, intestinal, and renal expression of bile acid transporters”, American Journal of Physiology - Renal Physiology. American Physiological Society, 306(1), pp. F130–137. doi: 10.1152/ajprenal.00114.2013.   edoc
Felser, A., Lindinger, P. W., Schnell, D., Kratschmar, D. V., Odermatt, A., Mies, S., Jenö, P. and Krähenbühl, S. (2014) “Hepatocellular toxicity of benzbromarone : Effects on mitochondrial function and structure”, Toxicology. Elsevier, Vol. 324, pp. 136–146. doi: 10.1016/j.tox.2014.08.002.   edoc
Chantong, B., Kratschmar, D. V., Lister, A. and Odermatt, A. (2014) “Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive G i -proteins in murine BV-2 microglia cells”, Journal of neuroinflammation. BioMed Central, Vol. 11, H. 1, p. 190. doi: 10.1186/s12974-014-0190-7.   edoc
Chantong, B., Kratschmar, D. V., Lister, A. and Odermatt, A. (2014) “Dibutyltin promotes oxidative stress and increases inflammatory mediators in BV-2 microglia cells”, Toxicology letters. Elsevier, Vol. 230, H. 2, pp. 177–187. doi: 10.1016/j.toxlet.2014.03.001.   edoc
Seibert, J., Hysek, C. M., Penno, C. A., Schmid, Y., Kratschmar, D. V., Liechti, M. E. and Odermatt, A. (2014) “Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects”, Neuroendocrinology. Karger, 100(1), pp. 17–25. doi: 10.1159/000364879.   edoc | Open Access
Vuorinen, A., Engeli, R., Meyer, A., Bachmann, F., Griesser, U. J., Schuster, D. and Odermatt, A. (2014) “Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors”, Journal of medicinal chemistry. American Chemical Society, Vol. 57, H. 14, pp. 5995–6007. doi: 10.1021/jm5004914.   edoc
Penno, C. A., Morgan, S. A., Rose, A. J., Herzig, S., Lavery, G. G. and Odermatt, A. (2014) “11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice”, Molecular metabolism. Elsevier, Vol. 3, H. 5, pp. 554–564. doi: 10.1016/j.molmet.2014.04.008.   edoc
Legeza, B., Balázs, Z. and Odermatt, A. (2014) “Fructose promotes the differentiation of 3T3-L1 adipocytes and accelerates lipid metabolism”, FEBS letters. Elsevier Science, Vol. 588, H. 3, pp. 490–496. doi: 10.1016/j.febslet.2013.12.014.   edoc
Birk, J., Meyer, M., Aller, I., Hansen, H. G., Odermatt, A., Dick, T. P., Meyer, A. J. and Appenzeller-Herzog, C. (2013) “Endoplasmic reticulum: reduced and oxidized glutathione revisited”, Journal of Cell Science. Company of Biologists, 126, pp. 1604–1617. doi: 10.1242/jcs.117218.   edoc | Open Access
Blüthgen, N., Sumpter, J. P., Odermatt, A. and Fent, K. (2013) “Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 2. Gene expression analysis and in vitro activity”, Aquatic Toxicology. Elsevier, 144-145, pp. 96–104. doi: 10.1016/j.aquatox.2013.09.030.   edoc
Hofer, S., Kratschmar, D. V., Schernthanner, B., Vuorinen, A., Schuster, D., Odermatt, A. and Easmon, J. (2013) “Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11β-hydroxysteroid dehydrogenase 1 inhibitors”, Bioorganic and Medicinal Chemistry Letters. Elsevier, 23(19), pp. 5397–5400. doi: 10.1016/j.bmcl.2013.07.047.   edoc
Leunig, M., Jüni, P., Werlen, S., Limacher, A., Nüesch, E., Pfirrmann, C. W., Trelle, S., Odermatt, A., Hofstetter, W., Ganz, R. and Reichenbach, S. (2013) “Prevalence of cam and pincer-type deformities on hip MRI in an asymptomatic young Swiss female population: a cross-sectional study”, Osteoarthritis and Cartilage . Saunders, 21(4), pp. 544–550. doi: 10.1016/j.joca.2013.01.003.   edoc
Vuorinen, A., Odermatt, A. and Schuster, D. (2013) “In silico methods in the discovery of endocrine disrupting chemicals”, Journal of Steroid Biochemistry and Molecular Biology. Elsevier, 137, pp. 18–26. doi: 10.1016/j.jsbmb.2013.04.009.   edoc
Sorensen, M. V., Grossmann, S., Roesinger, M., Gresko, N., Todkar, A. P., Barmettler, G., Ziegler, U., Odermatt, A., Loffing-Cueni, D. and Loffing, J. (2013) “Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice”, Kidney International. Elsevier, 83(5), pp. 811–824. doi: 10.1038/ki.2013.14.   edoc
Penno, C. A., Arsenijevic, D. D. C., Kullak-Ublick, G. A., Montani, J.-P. and Odermatt, A. (2013) “Quantification of multiple bile acids in uninephrectomized rats using ultra-performance liquid chromatography-tandem mass spectrometry”, Analytical Methods. Royal Society of Chemistry, 5, pp. 1155–1164. doi: 10.1039/C3AY26520J.   edoc | Open Access
Nashev, L. G., Atanasov, A. G., Baker, M. E. and Odermatt, A. (2013) “Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals”, International journal of cell biology. Hindawi, Vol. 2013 , art. 769536. doi: 10.1155/2013/769536.   edoc | Open Access
Meyer, A., Vuorinen, A., Zielinska, A. E., Strajhar, P., Lavery, G. G., Schuster, D. and Odermatt, A. (2013) “Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1”, Drug metabolism and disposition. Williams and Wilkins, Vol. 41, H. 9, pp. 1671–1678. doi: 10.1124/dmd.113.052936.   edoc
Birk, J., Ramming, T., Odermatt, A. and Appenzeller-Herzog, C. (2013) “Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise”, Frontiers in genetics. Frontiers Media, Vol. 4, art. 108 , 10 S., p. 108. doi: 10.3389/fgene.2013.00108.   edoc | Open Access
Penno, C. A., Morgan, S. A., Vuorinen, A., Schuster, D., Lavery, G. G. and Odermatt, A. (2013) “Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid”, Journal of Lipid Research. American Society for Biochemistry and Molecular Biology, 54(10), pp. 2874–2883. doi: 10.1194/jlr.M042499.   edoc | Open Access
Pandya, K., Dietrich, D., Seibert, J., Vederas, J. C. and Odermatt, A. (2013) “Synthesis of sterically encumbered 11β-aminoprogesterone derivatives and evaluation as 11β-hydroxysteroid dehydrogenase inhibitors and mineralocorticoid receptor antagonists”, Bioorganic & medicinal chemistry letters. Pergamon, Vol. 21, H. 21, pp. 6274–6281. doi: 10.1016/j.bmc.2013.08.068.   edoc
Meyer, A., Vuorinen, A., Zielinska, A. E., Da Cunha, T., Strajhar, P., Lavery, G. G., Schuster, D. and Odermatt, A. (2013) “Carbonyl reduction of triadimefon by human and rodent 11β-hydroxysteroid dehydrogenase 1”, Biochemical pharmacology. Pergamon Press, Vol. 85, H. 9, pp. 1370–1378. doi: 10.1016/j.bcp.2013.02.014.   edoc
Marchais-Oberwinkler, S., Xu, K., Wetzel, M., Perspicace, E., Negri, M., Meyer, A., Odermatt, A., Möller, G., Adamski, J. and Hartmann, R. W. (2013) “Structural Optimization of 2,5-Thiophene Amides as Highly Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors for the Treatment of Osteoporosis”, Journal of Medicinal Chemistry. American Chemical Society, Vol. 56, H. 1, pp. 167–181. doi: 10.1021/jm3014053.   edoc
Legeza, B., Balázs, Z., Nashev, L. G. and Odermatt, A. (2013) “The microsomal enzyme 17β-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase”, Endocrinology. Thomas, Vol. 154, H. 1, pp. 205–213. doi: 10.1210/en.2012-1778.   edoc
Odermatt, A. and Kratschmar, D. V. (2012) “Tissue-specific modulation of mineralocorticoid receptor function by 11β-hydroxysteroid dehydrogenases : an overview”, Molecular and cellular endocrinology. Elsevier, Vol. 350, H. 2, pp. 168–186. doi: 10.1016/j.mce.2011.07.020.   edoc
Chantong, B., Kratschmar, D. V., Nashev, L. G., Balazs, Z. and Odermatt, A. (2012) “Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells”, Journal of neuroinflammation. BioMed Central, Vol. 9, p. 260. doi: 10.1186/1742-2094-9-260.   edoc
Nashev, L. G., Vuorinen, A., Praxmarer, L., Chantong, B., Cereghetti, D., Winiger, R., Schuster, D. and Odermatt, A. (2012) “Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action”, PLoS ONE. Public Library of Science, Vol. 7, H. 10 , e46958. doi: 10.1371/journal.pone.0046958.   edoc
Fürstenberger, C., Vuorinen, A., Da Cunha, T., Kratschmar, D. V., Saugy, M., Schuster, D. and Odermatt, A. (2012) “The anabolic androgenic steroid fluoxymesterone inhibits 11β-hydroxysteroid dehydrogenase 2-dependent glucocorticoid inactivation”, Toxicological sciences. Oxford University Press, Vol. 126, H. 2, pp. 353–361. doi: 10.1093/toxsci/kfs022.   edoc
Veyrat-Durebex, C., Deblon, N., Caillon, A., Andrew, R., Altirriba, J., Odermatt, A. and Rohner-Jeanrenaud, F. (2012) “Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue”, PLoS ONE. Public Library of Science, Vol. 7, H. 3 , e34002. doi: 10.1371/journal.pone.0034002.   edoc
Meyer, A., Strajhar, P., Murer, C., Da Cunha, T. and Odermatt, A. (2012) “Species-specific differences in the inhibition of human and zebrafish 11β-hydroxysteroid dehydrogenase 2 by thiram and organotins”, Toxicology. Elsevier, Vol. 301, H. 1-3, pp. 72–78. doi: 10.1016/j.tox.2012.07.001.   edoc
Kratschmar, D. V., Calabrese, D., Walsh, J., Lister, A., Birk, J., Appenzeller-Herzog, C., Moulin, P., Goldring, C. E. and Odermatt, A. (2012) “Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells”, PLoS ONE. Public Library of Science, 7(5), p. e36774. doi: 10.1371/journal.pone.0036774.   edoc | Open Access
Blumberg, B., Iguchi, T. and Odermatt, A. (2011) “Endocrine disrupting chemicals”, The journal of steroid biochemistry and molecular biology. Pergamon, pp. 1–3.   edoc
Schuster, D., Kowalik, D., Kirchmair, J., Laggner, C., Markt, P., Aebischer-Gumy, C., Ströhle, F., Möller, G., Wolber, G., Wilckens, T., Langer, T., Odermatt, A. and Adamski, J. (2011) “Identification of chemically diverse, novel inhibitors of 17?-hydroxysteroid dehydrogenase type 3 and 5 by pharmacophore-based virtual screening”, The journal of steroid biochemistry and molecular biology. Elsevier Science, Vol. 125, H. 1-2, pp. 148–161.   edoc
Odermatt, A., Da Cunha, T., Penno, C. A., Chandsawangbhuwana, C., Reichert, C., Wolf, A., Dong, M. and Baker, M. E. (2011) “Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11?-hydroxysteroid dehydrogenase 1”, The Biochemical Journal. Portland Press, Vol. 436, H. 3, pp. 621–629.   edoc
Odermatt, A. (2011) “The Western-style diet : a major risk factor for impaired kidney function and chronic kidney disease”, American journal of physiology. Renal Physiology. American Physiological Society, Vol. 301, H. 5 , F919-931.   edoc
Gaware, R., Khunt, R., Czollner, L., Stanetty, C., Da Cunha, T., Kratschmar, D. V., Odermatt, A., Kosma, P., Jordis, U. and Classen-Houben, D. (2011) “Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors”, Bioorganic & medicinal chemistry. Elsevier, Vol. 19, H. 6, pp. 1866–1880.   edoc
Kratschmar, D. V., Vuorinen, A., Da Cunha, T., Wolber, G., Classen-Houben, D., Doblhoff, O., Schuster, D. and Odermatt, A. (2011) “Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11?-hydroxysteroid dehydrogenase type 2”, The journal of steroid biochemistry and molecular biology. Elsevier Science, Vol. 125, H. 1-2, pp. 129–142.   edoc
Reichenbach, S., Leunig, M., Werlen, S., Nüesch, E., Pfirrmann, C. W., Bonel, H., Odermatt, A., Hofstetter, W., Ganz, R. and Jüni, P. (2011) “Association between cam-type deformities and magnetic resonance imaging-detected structural hip damage : a cross-sectional study in young men”, Arthritis and rheumatism. Wiley-Liss, Vol. 63, H. 12, pp. 4023–4030.   edoc
Odermatt, A. and Nashev, L. G. (2010) “The glucocorticoid-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations”, The journal of steroid biochemistry and molecular biology. Pergamon, Vol. 119, H. 1-2, pp. 1–13.   edoc
Beseda, I., Czollner, L., Shah, P. S., Khunt, R., Gaware, R., Kosma, P., Stanetty, C., Del Ruiz-Ruiz, M. C., Amer, H., Mereiter, K., Da Cunha, T., Odermatt, A., Classen-Houben, D. and Jordis, U. (2010) “Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases”, Bioorganic & medicinal chemistry. Pergamon, Vol. 18, H. 1, pp. 433–454.   edoc
Rollinger, J. M., Kratschmar, D. V., Schuster, D., Pfisterer, P. H., Gumy, C., Aubry, E. M., Brandstötter, S., Stuppner, H., Wolber, G. and Odermatt, A. (2010) “11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches”, Bioorganic & medicinal chemistry. Pergamon, Vol. 18, H. 4, pp. 1507–1515.   edoc
Stanetty, C., Czollner, L., Koller, I., Shah, P., Gaware, R., Cunha, T. D., Odermatt, A., Jordis, U., Kosma, P. and Classen-Houben, D. (2010) “Synthesis of novel 3-amino and 29-hydroxamic acid derivatives of glycyrrhetinic acid as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors”, Bioorganic & medicinal chemistry. Pergamon, Vol. 18, H. 21, pp. 7522–7541.   edoc
Senesi, S., Legeza, B., Balázs, Z., Csala, M., Marcolongo, P., Kereszturi, E., Szelényi, P., Egger, C., Fulceri, R., Mandl, J., Giunti, R., Odermatt, A., Bánhegyi, G. and Benedetti, A. (2010) “Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum : possible implication in the metabolic syndrome”, Endocrinology. Thomas, Vol. 151, H. 10, pp. 4830–4839.   edoc
Reichenbach, S., Jüni, P., Werlen, S., Nüesch, E., Pfirrmann, C. W., Trelle, S., Odermatt, A., Hofstetter, W., Ganz, R. and Leunig, M. (2010) “Prevalence of cam-type deformity on hip magnetic resonance imaging in young males : a cross-sectional study”, Arthritis care & research. Wiley, Vol. 62, H. 9, pp. 1319–1327.   edoc
Nashev, L. G., Schuster, D., Laggner, C., Sodha, S., Langer, T., Wolber, G. and Odermatt, A. (2010) “The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3 : virtual screening as a strategy to identify potential endocrine disrupting chemicals”, Biochemical Pharmacology. Pergamon Press, Vol. 79, Issue 8, pp. 1189–1199.   edoc
Odermatt, A. and Atanasov, A. G. (2009) “Mineralocorticoid receptors : Emerging complexity and functional diversity”, Steroids. Holden-Day, Vol. 74, H. 2, pp. 163–171.   edoc
Odermatt, A. (2009) “Diazepane-acetamide derivatives as selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors”, Expert opinion on therapeutic patents. Informa Healthcare, Vol. 19, H. 10, pp. 1477–1483.   edoc
Dzyakanchuk, A. A., Balazs, Z., Nashev, L. G., Amrein, K. E. and Odermatt, A. (2009) “11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose”, Molecular and cellular endocrinology. Elsevier, Vol. 301, H. 1-2, pp. 137–141.   edoc
Balazs, Z., Nashev, L. G., Chandsawangbhuwana, C., Baker, M. E. and Odermatt, A. (2009) “Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1”, Molecular and cellular endocrinology. Elsevier, Vol. 301, H. 1-2, pp. 117–122.   edoc
Gumy, C., Thurnbichler, C., Aubry, E. M., Balazs, Z., Pfisterer, P., Baumgartner, L., Stuppner, H., Odermatt, A. and Rollinger, J. M. (2009) “Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines”, Fitoterapia. Elsevier Science, Vol. 80, no.3, pp. 200–205.   edoc
Classen-Houben, D., Schuster, D., Da Cunha, T., Odermatt, A., Wolber, G., Jordis, U. and Kueenburg, B. (2009) “Selective inhibition of 11beta-hydroxysteroid dehydrogenase 1 by 18alpha-glycyrrhetinic acid but not 18beta-glycyrrhetinic acid”, The journal of steroid biochemistry and molecular biology. Pergamon, Vol. 113, H. 3-5, pp. 248–252.   edoc
Atanasov, A. G., Nashev, L. G., Gelman, L., Legeza, B., Sack, R., Portmann, R. and Odermatt, A. (2008) “Direct protein-protein interaction of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen”, Biochimica et biophysica acta. Molecular cell research. Elsevier Science, Vol. 1783, Issue 8, pp. 1536–1543. doi: 10.1016/j.bbamcr.2008.03.001.   edoc
Schuster, D., Nashev, L. G., Kirchmair, J., Laggner, C., Wolber, G., Langer, T. and Odermatt, A. (2008) “Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries”, Journal of medicinal chemistry. American Chemical Society, Vol. 51, no. 14, pp. 4188–4199. doi: 10.1021/jm800054h.   edoc
Odermatt, A. and Gumy, C. (2008) “Glucocorticoid and mineralocorticoid action : Why should we consider influences by environmental chemicals?”, Biochemical Pharmacology. Pergamon Press, Volume 76, Issue 10, pp. 1184–1193. doi: 10.1016/j.bcp.2008.07.019.   edoc
Balazs, Z., Schweizer, R. A., Frey, F. J., Rohner-Jeanrenaud, F. and Odermatt, A. (2008) “DHEA induces 11beta-HSD2 by acting on CCAAT/enhancer-binding proteins”, Journal of the American Society of Nephrology. Williams and Wilkins, Vol. 19, H. 1, pp. 92–101.   edoc
Odermatt, A. and Gumy, C. (2008) “Disruption of glucocorticoid and mineralocorticoid receptor-mediated responses by environmental chemicals”, Chimia. Schweizerische Chemische Gesellschaft, 62(5), pp. 335–339. doi: 10.2533/chimia.2008.335.   edoc | Open Access
Gumy, C., Chandsawangbhuwana, C., Dzyakanchuk, A. A., Kratschmar, D. V., Baker, M. E. and Odermatt, A. (2008) “Dibutyltin disrupts glucocorticoid receptor function and impairs glucocorticoid-induced suppression of cytokine production”, PLoS ONE. Public Library of Science, Vol. 3, H. 10 , e3545.   edoc
Atanasov, A. G., Ignatova, I. D., Nashev, L. G., Dick, B., Ferrari, P., Frey, F. J. and Odermatt, A. (2007) “Impaired protein stability of 11beta-hydroxysteroid dehydrogenase type : a novel mechanism of apparent mineralocorticoid excess”, Journal of the American Society of Nephrology. Williams and Wilkins, Vol. 18, H. 4, pp. 1262–1270.   edoc
Nashev, L. G., Chandsawangbhuwana, C., Balazs, Z., Atanasov, A. G., Dick, B., Frey, F. J., Baker, M. E. and Odermatt, A. (2007) “Hexose-6-phosphate Dehydrogenase Modulates 11beta-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7beta-hydroxy-neurosteroids”, PLoS ONE. Public Library of Science, Vol. 2, H. 6 , e561.   edoc