Publications

Penny, M. A., Camponovo, F., Chitnis, N., Smith, T. A. and Tanner, M. (2020) “Future use-cases of vaccines in malaria control and elimination”, Parasite epidemiology and control. Elsevier, 10, p. e00145. doi: 10.1016/j.parepi.2020.e00145.   edoc | Open Access
Burgert, L., Rottmann, M., Wittlin, S., Gobeau, N., Krause, A., Dingemanse, J., Möhrle, J. J. and Penny, M. A. (2020) “Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development”, Scientific reports. Springer Nature, 10, p. 4410. doi: 10.1038/s41598-020-61304-8.   edoc | Open Access
Camponovo, F., Campo, J. J., Le, T. Q., Oberai, A., Hung, C., Pablo, J. V., Teng, A. A., Liang, X., Sim, B. K. L., Jongo, S., Abdulla, S., Tanner, M., Hoffman, S. L., Daubenberger, C. and Penny, M. A. (2020) “Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults”, eLife, 9, p. e53080. doi: 10.7554/eLife.53080.   
Galactionova, K., Velarde, M., Silumbe, K., Miller, J., McDonnell, A., Aguas, R., Smith, T. A. and Penny, M. A. (2020) “Costing malaria interventions from pilots to elimination programmes”, Malaria journal, 19, p. 332. doi: 10.1186/s12936-020-03405-3.   
Smith, T. A., Pemberton-Ross , P., Penny, M. A. and Chitnis, N. (2019) “Resurgence of malaria infection after mass treatment: a simulation study”, Malaria journal. BioMed Central, 18, p. 409. doi: 10.1186/s12936-019-3019-0.   edoc
Camponovo, F., Ockenhouse, C. F., Lee, C. and Penny, M. A. (2019) “Mass campaigns combining antimalarial drugs and anti-infective vaccines as seasonal interventions for malaria control, elimination and prevention of resurgence: a modelling study”, BMC infectious diseases. BioMed Central, 19, p. 920. doi: 10.1186/s12879-019-4467-4.   edoc | Open Access
Dietler, D., Leuenberger, A., Bempong, N.-E., Campbell-Lendrum, D., Cramer, C., Eggen, R. I. L., Erismann, S., Ferazzi, S., Flahault, A., Fletcher, H. A., Fuhrer, B., Fuhrimann, S., Greter, H., Heerdegen, A. C., Leach, M., Leissing, A., Lilje, J., Penny, M. A., Prytherch, H., Staudacher, P., Vounatsou, P., Weiss, F., Wiedemann, R., Winkler, M. S., Zhou, X.-N. and Utzinger, J. (2019) “Health in the 2030 Agenda for Sustainable Development : from framework to action, transforming challenges into opportunities”, Journal of global health. Edinburgh Univ. Global Health Soc, 9(2), p. 20201. doi: 10.7189/jogh.09.020201.   edoc | Open Access
Meister, I., Assawasuwannakit, P., Vanobberghen, F., Penny, M. A., Odermatt, P., Sayasone, S., Huwyler, J., Tarning, J. and Keiser, J. (2019) “Pooled population pharmacokinetic analysis of tribendimidine for the treatment of Opisthorchis viverrini infections”, Antimicrobial Agents and Chemotherapy. American Society for Microbiology, 63(4), pp. e01391–18. doi: 10.1128/AAC.01391-18.   edoc | Open Access
Stader, F., Penny, M. A., Siccardi, M. and Marzolini, C. (2019) “A comprehensive framework for physiologically based pharmacokinetic modelling in Matlab”., CPT: Pharmacometrics & Systems Pharmacology. Wiley, p. NA. doi: 10.1002/psp4.12399.   edoc | Open Access
Lee, T. E. and Penny, M. A. (2019) “Identifying key factors of the transmission dynamics of drug-resistant malaria”, Journal of theoretical biology. Elsevier, 462, pp. 210–220. doi: 10.1016/j.jtbi.2018.10.050.   edoc | Open Access
Stader, F., Siccardi, M., Battegay, M., Kinvig, H., Penny, M. A. and Marzolini, C. (2018) “Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes”, Clinical pharmacokinetics. Springer, p. NA. doi: 10.1007/s40262-018-0709-7.   edoc | Open Access
Ali, A. M., Penny, M. A., Smith, T. A., Workman, L., Sasi, P., Adjei, G. O., Aweeka, F., Kiechel, J.-R., Jullien, V., Rijken, M. J., McGready, R., Mwesigwa, J., Kristensen, K., Stepniewska, K., Tarning, J., Barnes, K. I., Denti, P. and Wwarn Amodiaquine PK Study Group (2018) “Population pharmacokinetics of the antimalarial amodiaquine: a pooled analysis to optimize dosing”, Antimicrobial agents and chemotherapy. American Society for Microbiology, 62(10), pp. e02193–17. doi: 10.1128/AAC.02193-17.   edoc | Open Access
Chitnis, N., Schapira, A., Schindler, C., Penny, M. A. and Smith, T. A. (2018) “Mathematical analysis to prioritise strategies for malaria elimination”, Journal of theoretical biology. Elsevier, 455, pp. 118–130. doi: 10.1016/j.jtbi.2018.07.007.   edoc | Open Access
Galactionova, K., Smith, T. A., de Savigny, D. and Penny, M. A. (2017) “State of inequality in malaria intervention coverage in sub-Saharan African countries”, BMC medicine. BioMed Central, 15, p. 185. doi: 10.1186/s12916-017-0948-8.   edoc | Open Access
Penny, M. and Smith, T. (2017) “Plasmodium falciparum mortality in Africa between 1990 and 2015”, The New England Journal of Medicine. Massachusetts Medical Society, 376, pp. 2493–2494. doi: 10.1056/NEJMc1701144.   edoc
Brady, O. J., Slater, H. C., Pemberton-Ross, P., Wenger, E., Maude, R. J., Ghani, A. C., Penny, M. A., Gerardin, J., White, L. J., Chitnis, N., Aguas, R., Hay, S. I., Smith, D. L., Stuckey, E. M., Smith, T. A. and Okell, L. C. (2017) “Model citizen – Authors’ reply”, Lancet. Global health. Elsevier, 5(10), p. e974.   edoc
Brady, O. J., Slater, H. C., Pemberton-Ross, P. J., Wenger, E., Maude, R. J., Ghani, A. C., Penny, M. A., Gerardin, J., White, L. J., Chitnis, N., Aguas, R., Hay, S. I., Smith, D. L., Stuckey, E. M., Okiro, E. A., Smith, T. A. and Okell, L. C. (2017) “Role of mass drug administration in elimination of Plasmodium falciparum malaria: a consensus modelling study”, Lancet Glob Health. Elsevier, 5(7), pp. e680-e687. doi: 10.1016/S2214-109X(17)30220-6.   edoc | Open Access
Smith, T. A., Chitnis, N., Penny, M. and Tanner, M. (2017) “Malaria modeling in the era of eradication”, Cold Spring Harbor perspectives in medicine. Cold Spring Harbor Laboratory Press, 7(4), p. a025460. doi: 10.1101/cshperspect.a025460.   edoc
Smith, T., Chitnis, N. and Penny, M. (2017) “Predictive malaria epidemiology : modeling malaria infection dynamics and impact of control interventions”, in Kremsner, P. G. and Krishna, S. (eds.) Encyclopedia of malaria. New York: Springer, pp. 1–10.   edoc
Galactionova, K., Tediosi, F., Camponovo, F., Smith, T. A., Gething, P. W. and Penny, M. A. (2017) “Country specific predictions of the cost-effectiveness of malaria vaccine RTS,S/AS01 in endemic Africa”, Vaccine. Elsevier, 35(1), pp. 53–60. doi: 10.1016/j.vaccine.2016.11.042.   edoc | Open Access
Camponovo, F., Bever, C. A., Galactionova, K., Smith, T. and Penny, M. A. (2017) “Incidence and admission rates for severe malaria and their impact on mortality in Africa”, Malaria journal. BioMed Central, 16, p. 1. doi: 10.1186/s12936-016-1650-6.   edoc | Open Access
Duthaler, U., Sayasone, S., Vanobbergen, F., Penny, M. A., Odermatt, P., Huwyler, J. and Keiser, J. (2016) “Single-ascending-Ddse pharmacokinetic study of tribendimidine in opisthorchis viverrini-infected patients”, Antimicrobial Agents and Chemotherapy. American Society for Microbiology, 60(10), pp. 5705–5715. doi: 10.1128/AAC.00992-16.   edoc
Duthaler, U., Sayasone, S., Vanobbergen, F., Penny, M. A., Odermatt, P., Huwyler, J. and Keiser, J. (2016) “Single ascending dose pharmacokinetic study of tribendimidine in Opisthorchis viverrini-infected patients”, Antimicrobial agents and chemotherapy. American Society for Microbiology, 60(10), pp. 5705–5715. doi: 10.1128/AAC.00992-16.   edoc
Vanobberghen, F., Penny, M. A., Duthaler, U., Odermatt, P., Sayasone, S., Keiser, J. and Tarning, J. (2016) “Population pharmacokinetic modeling of tribendimidine metabolites in opisthorchis viverrini-Infected adults”, Antimicrobial agents and chemotherapy. American Society for Microbiology, 60(10), pp. 5695–5704. doi: 10.1128/AAC.00655-16.   edoc
Tediosi, F. and Penny, M. (2016) “Evidence for optimal allocation of malaria interventions in Africa”, Lancet. Global health. Elsevier, pp. e432-e433. doi: 10.1016/S2214-109X(16)30108-5.   edoc
Penny, M. A., Verity, R., Bever, C. A., Sauboin, C., Galactionova, K., Flasche, S., White, M. T., Wenger, E. A., Van de Velde, N., Pemberton-Ross, P., Griffin, J. T., Smith, T. A., Eckhoff, P. A., Muhib, F., Jit, M. and Ghani, A. C. (2016) “Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine : a systematic comparison of predictions from four mathematical models”, Lancet, 387(10016), pp. 367–375. doi: 10.1016/S0140-6736(15)00725-4.   edoc
Okell, L., Slater, H., Ghani, A., Pemberton-Ross, P., Smith, T. A., Chitnis, N., Penny, M. A., Wenger, E., Garardin, J., Maude, R., Aguas, R., White, L., Brady, O., Hay, S., Okiro, E. and Kern, S. (2015) “Consensus modelling evidence to support the design of mass drug administration programmes”, Malaria Policy Advisory Committee meeting, 16-18 September 2015, Geneva Switzerland, Background document for Session 1. Geneva: World Health Organization.   edoc
Bhatt, S., Weiss, D. J., Cameron, E., Bisanzio, D., Mappin, B., Dalrymple, U., Battle, K. E., Moyes, C. L., Henry, A., Eckhoff, P. A., Wenger, E. A., Briët, O., Penny, M. A., Smith, T. A., Bennett, A., Yukich, J., Eisele, T. P., Griffin, J. T., Fergus, C. A., Lynch, M., Lindgren, F., Cohen, J. M., Murray, C. L. J., Smith, D. L., Hay, S. I., Cibulskis, R. E. and Gething, P. W. (2015) “The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015”, Nature. Macmillan, 526(7572), pp. 207–211. doi: 10.1038/nature15535.   edoc
Penny, M. A., Pemberton-Ross, P. and Smith, T. A. (2015) “The time-course of protection of the RTS,S vaccine against malaria infections and clinical disease”, Malaria journal. BioMed Central, 14, p. 437. doi: 10.1186/s12936-015-0969-8.   edoc | Open Access
Penny, M. A., Maire, N., Bever, C. A., Pemberton-Ross, P., Briët, O. J. T., Smith, D. L., Gething, P. W. and Smith, T. A. (2015) “Distribution of malaria exposure in endemic countries in Africa considering country levels of effective treatment”, Malaria journal. BioMed Central, Vol. 14 , 384. doi: 10.1186/s12936-015-0864-3.   edoc | Open Access
Cameron, E., Battle, K. E., Bhatt, S., Weiss, D. J., Bisanzio, D., Mappin, B., Dalrymple, U., Hay, S. I., Smith, D. L., Griffin, J. T., Wenger, E. A., Eckhoff, P. A., Smith, T. A., Penny, M. A. and Gething, P. W. (2015) “Defining the relationship between infection prevalence and clinical incidence of Plasmodium falciparum malaria”, Nature communications. Nature Publishing Group, Vol. 6 , Article Nr. 8170. doi: 10.1038/ncomms9170.   edoc
Pemberton-Ross, P., Smith, T. A., Hodel, E. M., Kay, K. and Penny, M. A. (2015) “Age-shifting in malaria incidence as a result of induced immunological deficit : a simulation study”, Malaria journal. BioMed Central, Vol. 14 , 287. doi: 10.1186/s12936-015-0805-1.   edoc | Open Access
Penny, M. A., Galactionova, K., Tarantino, M., Tanner, M. and Smith, T. A. (2015) “The public health impact of malaria vaccine RTS,S in malaria endemic Africa : country-specific predictions using 18 month follow-up Phase III data and simulation models”, BMC medicine. BioMed Central, Vol. 13 , 170. doi: 10.1186/s12916-015-0408-2.   edoc | Open Access
Briët, O. J., Penny, M. A., Hardy, D., Awolola, T. S., Van Bortel, W., Corbel, V., Dabiré, R. K., Etang, J., Koudou, B. G., Tungu, P. K. and Chitnis, N. (2013) “Effects of pyrethroid resistance on the cost effectiveness of a mass distribution of long-lasting insecticidal nets : a modelling study”, Malaria journal. BioMed Central, Vol. 12 , 77. doi: 10.1186/1475-2875-12-77.   edoc