Publications

Battilana, F., Steurer, S., Rizzi, G., Delgado, A. C., Tan, K. R. and Handschin, C. (2020) “Exercise-linked improvement in age-associated loss of balance is associated with increased vestibular input to motor neurons”, Aging Cell. Wiley, 19(12), p. e13274. doi: 10.1111/acel.13274.   
Rizzi, G. and Tan, K. R. (2019) “Synergistic Nigral Output Pathways Shape Movement”, Cell reports. Cell Press, 27(7), pp. 2184–2198.e4. doi: 10.1016/j.celrep.2019.04.068.   edoc
Rizzi, G., Coban, M. and Tan, K. R. (2019) “Excitatory rubral cells encode the acquisition of novel complex motor tasks”, Nature communications. Nature Publishing Group, 10(1), p. 2241. doi: 10.1038/s41467-019-10223-y.   edoc
Kojima, R., Bojar, D., Rizzi, G., Hamri, G. C.-E., El-Baba, M. D., Saxena, P., Ausländer, S., Tan, K. R. and Fussenegger, M. (2018) “Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment”, Nature communications, 9(1), p. 1305. doi: 10.1038/s41467-018-03733-8.   edoc
Rizzi, G. and Tan , K. R. (2017) “Dopamine and Acetylcholine, a Circuit Point of View in Parkinson’s Disease”, Frontiers in Neural Circuits. Frontiers Media, 11(110), pp. 1–14. doi: 10.3389/fncir.2017.00110.   edoc | Open Access
Rizzi, G., Lodge, M. E. and Tan, K. R. (2016) “Design and construction of a low-cost nose poke system for rodents”, MethodsX. Elsevier, 3, pp. 326–632. doi: 10.1016/j.mex.2016.04.002.   edoc
Lalive, A. L., Munoz, M. B., Bellone, C., Slesinger, P. A., Lüscher, C. and Tan, K. R. (2014) “Firing modes of dopamine neurons drive bidirectional GIRK channel plasticity”, Journal of Neuroscience. Society for Neuroscience, 34(15), pp. 5107–5114. doi: 10.1523/JNEUROSCI.5203-13.2014.   edoc
Creed, M. C., Ntamati, N. R. and Tan, K. R. (2014) “VTA GABA neurons modulate specific learning behaviors through the control of dopamine and cholinergic systems”, Frontiers in Behavioral Neuroscience. Frontiers Media, 8, p. 8. doi: 10.3389/fnbeh.2014.00008.   edoc
Bocklisch, C., Pascoli, V., Wong, J. C. Y., House, D. R. C., Yvon, C., de Roo, M., Tan, K. R. and Lüscher, C. (2013) “Cocaine disinhibits dopamine neurons by potentiation of GABA transmission in the ventral tegmental area”, Science. American Association for the Advancement of Science, 341(6153), pp. 1521–1525. doi: 10.1126/science.1237059.   edoc
Padgett, C. L., Lalive, A. L., Tan, K. R., Terunuma, M., Munoz, M. B., Pangalos, M. N., Martínez-Hernández, J., Watanabe, M., Moss, S. J., Luján, R., Lüscher, C. and Slesinger, P. A. (2012) “Methamphetamine-evoked depression of GABA(B) receptor signaling in GABA neurons of the VTA”, Neuron. Elsevier, 73(5), pp. 978–989. doi: 10.1016/j.neuron.2011.12.031.   edoc
Tan, K. R., Yvon, C., Turiault, M., Mirzabekov, J. J., Doehner, J., Labouèbe, G., Deisseroth, K., Tye, K. M. and Lüscher, C. (2012) “GABA neurons of the VTA drive conditioned place aversion”, Neuron. Elsevier, 73(6), pp. 1173–1183. doi: 10.1016/j.neuron.2012.02.015.   edoc
Brown, M. T. C., Tan, K. R., O’Connor, E. C., Nikonenko, I., Muller, D. and Lüscher, C. (2012) “Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning”, Nature. Macmillan, 492(7429), pp. 452–456. doi: 10.1038/nature11657.   edoc
Lalive, A. L., Rudolph, U., Lüscher, C. and Tan, K. R. (2011) “Is there a way to curb benzodiazepine addiction?”, Swiss Medical Weekly. EMH Schweizerischer Arzteverlag , p. w13277. doi: 10.4414/smw.2011.13277.   edoc
Tan, K. R., Rudolph, U. and Lüscher, C. (2011) “Hooked on benzodiazepines: GABAA receptor subtypes and addiction”, Trends in Neurosciences. Elsevier, 34(4), pp. 188–197. doi: 10.1016/j.tins.2011.01.004.   edoc
Tan, K. R., Brown, M., Labouèbe, G., Yvon, C., Creton, C., Fritschy, J.-M., Rudolph, U. and Lüscher, C. (2010) “Neural bases for addictive properties of benzodiazepines”, Nature. Macmillan, 463(7282), pp. 769–774. doi: 10.1038/nature08758.   edoc
Tan, K. R., Baur, R., Charon, S., Goeldner, M. and Sigel, E. (2009) “Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors”, Journal of Neurochemistry. Wiley-Blackwell, 111(5), pp. 1264–1273. doi: 10.1111/j.1471-4159.2009.06419.x.   edoc
Baur, R., Tan, K. R., Lüscher, B. P., Gonthier, A., Goeldner, M. and Sigel, E. (2008) “Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs”, Journal of Neurochemistry. Wiley, 106(6), pp. 2353–2363. doi: 10.1111/j.1471-4159.2008.05574.x.   edoc
Tan, K. R., Baur, R., Gonthier, A., Goeldner, M. and Sigel, E. (2007) “Two neighboring residues of loop A of the alpha1 subunit point towards the benzodiazepine binding site of GABAA receptors”, FEBS Letters. Elsevier, 581(24), pp. 4718–4722. doi: 10.1016/j.febslet.2007.08.068.   edoc
Tan, K. R., Gonthier, A., Baur, R., Ernst, M., Goeldner, M. and Sigel, E. (2007) “Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators”, Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 282(36), pp. 26316–26325. doi: 10.1074/jbc.M702153200.   edoc
Laffray, S., Tan, K., Dulluc, J., Bouali-Benazzouz, R., Calver, A. R., Nagy, F. and Landry, M. (2007) “Dissociation and trafficking of rat GABAB receptor heterodimer upon chronic capsaicin stimulation”, European Journal of Neuroscience. Wiley, 25(5), pp. 1402–1416. doi: 10.1111/j.1460-9568.2007.05398.x.   edoc
Tan, K., Guibert, C., Neaud, V. and Rosenbaum, J. (2003) “Hepatitis C virus proteins do not directly trigger fibrogenic events in cultured human liver myofibroblasts”, Journal of Viral Hepatitis. Wiley, 10(6), pp. 427–432. doi: 10.1046/j.1365-2893.2003.00460.x.   edoc